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Low-Rank Adaptation (LoRA) has become the leading Parameter-Efficient Fine-Tuning (PEFT) method for Large Language Models (LLMs), as it significantly reduces GPU memory usage while maintaining competitive fine-tuned model quality on…

Machine Learning · Computer Science 2025-10-02 Zhanda Zhu , Qidong Su , Yaoyao Ding , Kevin Song , Shang Wang , Gennady Pekhimenko

Existing pruning techniques for large language models (LLMs) targeting domain-specific applications typically follow a two-stage process: pruning the pretrained general-purpose LLMs and then fine-tuning the pruned LLMs on specific domains.…

Computation and Language · Computer Science 2024-12-23 Lei Lu , Zhepeng Wang , Runxue Bao , Mengbing Wang , Fangyi Li , Yawen Wu , Weiwen Jiang , Jie Xu , Yanzhi Wang , Shangqian Gao

Parameter-efficient fine-tuning (PEFT) techniques such as low-rank adaptation (LoRA) can effectively adapt large pre-trained foundation models to downstream tasks using only a small fraction (0.1%-10%) of the original trainable weights. An…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Samar Khanna , Medhanie Irgau , David B. Lobell , Stefano Ermon

Large Language Models (LLMs) have demonstrated impressive performance across various domains. However, the enormous number of model parameters makes fine-tuning challenging, significantly limiting their application and deployment. Existing…

Machine Learning · Computer Science 2025-07-23 Ao Shen , Qiang Wang , Zhiquan Lai , Xionglve Li , Dongsheng Li

Fine-tuning Large Language Models (LLMs) with Low-Rank Adaptation (LoRA) enhances adaptability while reducing computational costs. However, fine-tuning can compromise safety alignment, even with benign data, increasing susceptibility to…

Machine Learning · Computer Science 2025-06-25 Shuang Ao , Yi Dong , Jinwei Hu , Sarvapali Ramchurn

Tabular data are crucial in many fields and their understanding by large language models (LLMs) under high parameter efficiency paradigm is important. However, directly applying parameter-efficient fine-tuning (PEFT) techniques to tabular…

Computation and Language · Computer Science 2025-06-30 Xinyi He , Yihao Liu , Mengyu Zhou , Yeye He , Haoyu Dong , Shi Han , Zejian Yuan , Dongmei Zhang

Protein Language Models (PLMs) have emerged as performant and scalable tools for predicting the functional impact and clinical significance of protein-coding variants, but they still lag experimental accuracy. Here, we present a novel…

In fine-tuning large language models (LLMs), conserving computational resources while maintaining effectiveness and improving outcomes within the same computational constraints is crucial. The Low-Rank Adaptation (LoRA) strategy balances…

Machine Learning · Computer Science 2024-09-05 Xiaojun Xiao , Sen Shen , Qiming Bao , Hongfei Rong , Kairui Liu , Zhongsheng Wang , Jiamou Liu

Fine-tuning is the primary methodology for tailoring pre-trained large language models to specific tasks. As the model's scale and the diversity of tasks expand, parameter-efficient fine-tuning methods are of paramount importance. One of…

Machine Learning · Computer Science 2024-01-10 Wenhan Xia , Chengwei Qin , Elad Hazan

Pre-trained Language Models (PLMs) can be accurately fine-tuned for downstream text processing tasks. Recently, researchers have introduced several parameter-efficient fine-tuning methods that optimize input prompts or adjust a small number…

Computation and Language · Computer Science 2024-06-07 Saeed Najafi , Alona Fyshe

The Parameter-Efficient Fine-Tuning (PEFT) methods have been extensively researched for large language models in downstream tasks. Among all the existing approaches, the Low-Rank Adaptation (LoRA) has gained popularity for its streamlined…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Tangyu Jiang , Haodi Wang , Chun Yuan

Parameter Efficient Fine-Tuning (PEFT) methods are proposed as an alternative fine-tuning approach for Large Language Models (LLM) to minimize high training costs. While prior research demonstrates the effectiveness of PEFT methods in…

Software Engineering · Computer Science 2025-01-28 Amirreza Esmaeili , Iman Saberi , Fatemeh H. Fard

The growth of large language models underscores the need for parameter-efficient fine-tuning. Despite its popularity, LoRA encounters storage and computational challenges when deploying multiple task- or user-specific modules. To address…

Machine Learning · Computer Science 2025-08-21 Klaudia Bałazy , Mohammadreza Banaei , Karl Aberer , Jacek Tabor

Among the widely used parameter-efficient fine-tuning (PEFT) methods, LoRA and its variants have gained considerable popularity because of avoiding additional inference costs. However, there still often exists an accuracy gap between these…

Computation and Language · Computer Science 2024-07-10 Shih-Yang Liu , Chien-Yi Wang , Hongxu Yin , Pavlo Molchanov , Yu-Chiang Frank Wang , Kwang-Ting Cheng , Min-Hung Chen

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

Biomolecules · Quantitative Biology 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang

Low-rank adaptation (LoRA) has become the default approach to fine-tune large language models (LLMs) due to its significant reduction in trainable parameters. However, trainable parameter demand for LoRA increases with increasing model…

Computation and Language · Computer Science 2024-06-19 Seyedarmin Azizi , Souvik Kundu , Massoud Pedram

This paper develops an ensemble method for fine-tuning a language model to multiple datasets. Existing methods, such as quantized LoRA (QLoRA), are efficient when adapting to a single dataset. When training on multiple datasets of different…

Machine Learning · Computer Science 2025-05-29 Dongyue Li , Ziniu Zhang , Lu Wang , Hongyang R. Zhang

Low-rank adaptation (LoRA) has been developed as an efficient approach for adapting large language models (LLMs) by fine-tuning two low-rank matrices, thereby reducing the number of trainable parameters. However, prior research indicates…

Computation and Language · Computer Science 2026-04-13 Lin Mu , Xiaoyu Wang , Li Ni , Yang Li , Zhize Wu , Peiquan Jin , Yiwen Zhang

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

We report a mixture of expert strategy to create fine-tuned large language models using a deep layer-wise token-level approach based on low-rank adaptation (LoRA). Starting with a set of pre-trained LoRA adapters, our gating strategy uses…

Soft Condensed Matter · Physics 2024-04-02 Eric L. Buehler , Markus J. Buehler