English
Related papers

Related papers: SeqProFT: Sequence-only Protein Property Predictio…

200 papers

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

Finetuning Large Language Models helps improve the results for domain-specific use cases. End-to-end finetuning of large language models is time and resource intensive and has high storage requirements to store the finetuned version of the…

Computation and Language · Computer Science 2023-07-12 Kunal Suri , Prakhar Mishra , Saumajit Saha , Atul Singh

In addressing the computational and memory demands of fine-tuning Large Language Models(LLMs), we propose LoRA-SP(Streamlined Partial Parameter Adaptation), a novel approach utilizing randomized half-selective parameter freezing within the…

Machine Learning · Computer Science 2024-03-15 Yichao Wu , Yafei Xiang , Shuning Huo , Yulu Gong , Penghao Liang

Protein language models (PLMs) have advanced computational protein science through large-scale pretraining and scalable architectures. In parallel, reinforcement learning (RL) has broadened exploration and enabled precise multi-objective…

An important paradigm of natural language processing consists of large-scale pre-training on general domain data and adaptation to particular tasks or domains. As we pre-train larger models, full fine-tuning, which retrains all model…

Computation and Language · Computer Science 2021-10-19 Edward J. Hu , Yelong Shen , Phillip Wallis , Zeyuan Allen-Zhu , Yuanzhi Li , Shean Wang , Lu Wang , Weizhu Chen

Large Language Models (LLMs), being generic task solvers, are versatile. However, despite the vast amount of data they are trained on, there are speculations about their adaptation capabilities to a new domain. Additionally, the simple…

Computation and Language · Computer Science 2025-09-03 Anum Afzal , Mehul Kumawat , Florian Matthes

While large language models (LLMs) such as Llama-2 or GPT-4 have shown impressive zero-shot performance, fine-tuning is still necessary to enhance their performance for customized datasets, domain-specific tasks, or other private needs.…

Machine Learning · Computer Science 2025-01-07 Chia-Yi Hsu , Yu-Lin Tsai , Chih-Hsun Lin , Pin-Yu Chen , Chia-Mu Yu , Chun-Ying Huang

Large Language Models (LLMs) have significantly advanced natural language processing with exceptional task generalization capabilities. Low-Rank Adaption (LoRA) offers a cost-effective fine-tuning solution, freezing the original model…

Machine Learning · Computer Science 2025-03-18 Jun Zhang , Jue Wang , Huan Li , Lidan Shou , Ke Chen , Yang You , Guiming Xie , Xuejian Gong , Kunlong Zhou

The rapid progress of large language models (LLMs) has transformed natural language processing, yet the challenge of efficient adaptation remains unresolved. Full fine-tuning achieves strong performance but imposes prohibitive computational…

Quantum Physics · Physics 2025-09-23 Emily Jimin Roh , Hyojun Ahn , Samuel Yen-Chi Chen , Soohyun Park , Joongheon Kim

Large language models (LLMs) face the challenges in fine-tuning and deployment due to their high memory demands and computational costs. While parameter-efficient fine-tuning (PEFT) methods aim to reduce the memory usage of the optimizer…

Machine Learning · Computer Science 2023-10-31 Jeonghoon Kim , Jung Hyun Lee , Sungdong Kim , Joonsuk Park , Kang Min Yoo , Se Jung Kwon , Dongsoo Lee

Fine-tuning Large Language Models (LLMs) has become increasingly challenging due to their massive scale and associated computational costs. Parameter-Efficient Fine-Tuning (PEFT) methodologies have been proposed as computational…

Computation and Language · Computer Science 2025-05-22 Jialong Han , Si Zhang , Ke Zhang

Smaller LLMs still face significant challenges even in medium-resourced languages, particularly when it comes to language-specific knowledge -- a problem not easily resolved with machine-translated data. In this case study on Icelandic, we…

Computation and Language · Computer Science 2024-12-18 Jenny Kunz

In this paper, we introduce \textbf{Share}d \textbf{Lo}w \textbf{R}ank \textbf{A}daptation (ShareLoRA), a Large Language Model (LLM) fine-tuning technique that balances parameter efficiency, adaptability, and robustness without compromising…

Computation and Language · Computer Science 2025-05-20 Yurun Song , Junchen Zhao , Ian G. Harris , Sangeetha Abdu Jyothi

Parameter-efficient finetuning (PEFT) aims to mitigate the substantial computational and memory overhead involved in adapting large-scale pretrained models to diverse downstream tasks. Among numerous PEFT strategies, Low-Rank Adaptation…

Artificial Intelligence · Computer Science 2025-10-10 Xiaoshuang Ji , Zhendong Zhao , Xiaoyan Gu , Xiaojun Chen , Xin Zhao , Zeyao Liu

As large language models (LLMs) continue to scale in size, the computational overhead has become a major bottleneck for task-specific fine-tuning. While low-rank adaptation (LoRA) effectively curtails this cost by confining the weight…

Machine Learning · Computer Science 2026-05-15 Yilang Zhang , Xiaodong Yang , Yiwei Cai , Georgios B. Giannakis

This paper investigates and validates the impact of fine-tuning on large language model performance, focusing on parameter-efficient methods (LoRA and QLoRA). We evaluate model capabilities across three key domains: (1) commonsense…

Computation and Language · Computer Science 2025-06-13 Qingda , Mai

This study proposes a large language model optimization method based on the improved LoRA fine-tuning algorithm, aiming to improve the accuracy and computational efficiency of the model in natural language processing tasks. We fine-tune the…

Computation and Language · Computer Science 2024-12-30 Jiacheng Hu , Xiaoxuan Liao , Jia Gao , Zhen Qi , Hongye Zheng , Chihang Wang

Supervised fine-tuning is the most common method to adapt large language models (LLMs) to downstream tasks, but full fine-tuning LLMs requires massive computational resources. Recently, parameter-efficient fine-tuning (PEFT) methods have…

Computation and Language · Computer Science 2024-02-27 Xiangdi Meng , Damai Dai , Weiyao Luo , Zhe Yang , Shaoxiang Wu , Xiaochen Wang , Peiyi Wang , Qingxiu Dong , Liang Chen , Zhifang Sui

The increasing size of language models raises great research interests in parameter-efficient fine-tuning such as LoRA that freezes the pre-trained model, and injects small-scale trainable parameters for multiple downstream tasks (e.g.,…

Computation and Language · Computer Science 2023-05-22 Yunqi Zhu , Xuebing Yang , Yuanyuan Wu , Wensheng Zhang

Low-rank adaptation (LoRA) has emerged as the de facto standard for parameter-efficient fine-tuning (PEFT) of foundation models, enabling the adaptation of billion-parameter networks with minimal computational and memory overhead. Despite…

Machine Learning · Computer Science 2026-04-24 Bingcong Li , Yilang Zhang , Georgios B. Giannakis