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This paper studies a Markov network model for unbalanced data, aiming to solve the problems of classification bias and insufficient minority class recognition ability of traditional machine learning models in environments with uneven class…

Machine Learning · Computer Science 2025-02-06 Junliang Du , Shiyu Dou , Bohuan Yang , Jiacheng Hu , Tai An

Methods to correct class imbalance, i.e. imbalance between the frequency of outcome events and non-events, are receiving increasing interest for developing prediction models. We examined the effect of imbalance correction on the performance…

Methodology · Statistics 2022-02-21 Ruben van den Goorbergh , Maarten van Smeden , Dirk Timmerman , Ben Van Calster

While current research has shown the importance of Multi-parametric MRI (mpMRI) in diagnosing prostate cancer (PCa), further investigation is needed for how to incorporate the specific structures of the mpMRI data, such as the regional…

Machine Learning · Statistics 2021-11-04 Jin Jin , Lin Zhang , Ethan Leng , Gregory J. Metzger , Joseph S. Koopmeiners

Random Forest is a machine learning method that offers many advantages, including the ability to easily measure variable importance. Class balancing technique is a well-known solution to deal with class imbalance problem. However, it has…

Machine Learning · Statistics 2023-12-19 Yunbi Nam , Sunwoo Han

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Medical question answering requires advanced reasoning that integrates domain knowledge with logical inference. However, existing large language models (LLMs) often generate reasoning chains that lack factual accuracy and clinical…

Computation and Language · Computer Science 2025-12-09 Chia-Hsuan Hsu , Jun-En Ding , Hsin-Ling Hsu , Chih-Ho Hsu , Li-Hung Yao , Chun-Chieh Liao , Feng Liu , Fang-Ming Hung

The classification of clinical notes into specific diagnostic categories is critical in healthcare, especially for mental health conditions like Anxiety and Adjustment Disorder. In this study, we compare the performance of various…

In biostatistics, propensity score is a common approach to analyze the imbalance of covariate and process confounding covariates to eliminate differences between groups. While there are an abundant amount of methods to compute propensity…

Methodology · Statistics 2018-01-11 Chen Wang , Suzhen Wang , Fuyan Shi , Zaixiang Wang

Stroke remains one of the most critical global health challenges, ranking as the second leading cause of death and the third leading cause of disability worldwide. This study explores the effectiveness of machine learning algorithms in…

Machine Learning · Computer Science 2025-05-16 Anastasija Tashkova , Stefan Eftimov , Bojan Ristov , Slobodan Kalajdziski

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Understanding and managing uncertainty is crucial in machine learning, especially in high-stakes domains like healthcare, where class imbalance can impact predictions. This paper introduces RIGA, a novel pipeline that mitigates class…

Machine Learning · Computer Science 2025-03-06 Mahdi Arab Loodaricheh , Neh Majmudar , Anita Raja , Ansaf Salleb-Aouissi

Data imbalance between common and rare diseases during model training often causes intelligent diagnosis systems to have biased predictions towards common diseases. The state-of-the-art approaches apply a two-stage learning framework to…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Chenghua Zeng , Huijuan Lu , Kanghao Chen , Ruixuan Wang , Wei-Shi Zheng

Multistate process data are common in studies of chronic diseases such as cancer. These data are ideal for precision medicine purposes as they can be leveraged to improve more refined health outcomes, compared to standard survival outcomes,…

Methodology · Statistics 2022-11-28 Giorgos Bakoyannis

Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-16 Saeid Asgari Taghanaki , Yefeng Zheng , S. Kevin Zhou , Bogdan Georgescu , Puneet Sharma , Daguang Xu , Dorin Comaniciu , Ghassan Hamarneh

As deep neural networks include a high number of parameters and operations, it can be a challenge to implement these models on devices with limited computational resources. Despite the development of novel pruning methods toward…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Morteza Homayounfar , Mohamad Koohi-Moghadam , Reza Rawassizadeh , Varut Vardhanabhuti

In the relentless efforts in enhancing medical diagnostics, the integration of state-of-the-art machine learning methodologies has emerged as a promising research area. In molecular biology, there has been an explosion of data generated…

Machine Learning · Computer Science 2024-05-17 Ibrahim Al-Hurani , Abedalrhman Alkhateeb , Salama Ikki

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang

In cancer epidemiology using population-based data, regression models for the excess mortality hazard is a useful method to estimate cancer survival and to describe the association between prognosis factors and excess mortality. This method…

Methodology · Statistics 2019-04-19 Francisco J. Rubio , Bernard Rachet , Roch Giorgi , Camille Maringe , Aurelien Belot

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering
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