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Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…

Machine Learning · Computer Science 2015-09-30 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

The nature of clinical data makes it difficult to quickly select, tune and apply machine learning algorithms to clinical prognosis. As a result, a lot of time is spent searching for the most appropriate machine learning algorithms…

Machine Learning · Computer Science 2015-04-21 Kwetishe Joro Danjuma

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…

With medical tests becoming increasingly available, concerns about over-testing and over-treatment dramatically increase. Hence, it is important to understand the influence of testing on treatment selection in general practice. Most…

Methodology · Statistics 2020-08-11 Yun Li , Irina Bondarenko , Michael R. Elliott , Timothy P. Hofer , Jeremy M. G. Taylor

Class imbalance remains a critical challenge in machine learning (ML), particularly in the medical domain, where underrepresented minority classes lead to biased models and reduced predictive performance. This study introduces…

Machine Learning · Computer Science 2025-09-04 Vikas Kashtriya , Pardeep Singh

Multiple organ failure (MOF) is a life-threatening condition. Due to its urgency and high mortality rate, early detection is critical for clinicians to provide appropriate treatment. In this paper, we perform quantitative analysis on early…

Machine Learning · Computer Science 2021-04-26 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Recent advances in genomic sequencing technology have resulted in an abundance of genome sequence data. Despite the progress in interpreting those data, there remains a broad scope for their translation into clinical and societal benefits.…

Genomics · Quantitative Biology 2021-12-13 Abhinav Jain , Greg Slabaugh , Deepti Gurdasani

Lung cancer patients frequently experience breakthrough pain episodes, with up to 91% requiring timely intervention. To enable proactive pain management, we propose a hybrid machine learning and large language model pipeline that predicts…

Artificial Intelligence · Computer Science 2026-05-22 Yipeng Zhuang , Yifeng Guo , Yuewen Li , Yuheng Wu , Philip Leung-Ho Yu , Tingting Song , Zhiyong Wang , Kunzhong Zhou , Weifang Wang , Li Zhuang

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Background: Accurate survival time estimates aid end-of-life medical decision-making. Objectives: Develop an interpretable survival model for elderly residential aged care residents using advanced machine learning. Setting: A major…

Machine Learning · Computer Science 2023-12-11 Teo Susnjak , Elise Griffin

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Weiwei Zong , Joon Lee , Chang Liu , Eric Carver , Aharon Feldman , Branislava Janic , Mohamed Elshaikh , Milan Pantelic , David Hearshen , Indrin Chetty , Benjamin Movsas , Ning Wen

Artificial intelligence may assist healthcare systems in meeting increasing demand for pathology services while maintaining diagnostic quality and reducing turnaround time and costs. We aimed to investigate the performance of an…

Machine Learning applications have brought new insights into a secondary analysis of medical data. Machine Learning helps to develop new drugs, define populations susceptible to certain illnesses, identify predictors of many common…

Machine Learning · Computer Science 2020-12-29 YuanZheng Hu , Marina Sokolova

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize…

Machine Learning · Computer Science 2018-07-10 Matthew Yung , Eli T. Brown , Alexander Rasin , Jacob D. Furst , Daniela S. Raicu

A Pathology report is arguably one of the most important documents in medicine containing interpretive information about the visual findings from the patient's biopsy sample. Each pathology report has a retention period of up to 20 years…

Computation and Language · Computer Science 2019-03-19 Shivam Kalra , Larry Li , Hamid R. Tizhoosh

Medical images commonly exhibit multiple abnormalities. Predicting them requires multi-class classifiers whose training and desired reliable performance can be affected by a combination of factors, such as, dataset size, data source,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Sameer Antani