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Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

Quantitative Methods · Quantitative Biology 2025-07-31 Gianluca Carloni , Biagio Brattoli , Seongho Keum , Jongchan Park , Taebum Lee , Chang Ho Ahn , Sergio Pereira

Large AI models have been widely adopted in wireless communications for channel modeling, beamforming, and resource optimization. However, most existing efforts remain limited to single-modality inputs and channel-specific objec- tives,…

Machine Learning · Computer Science 2025-11-18 Zhizhen Li , Xuanhao Luo , Xueren Ge , Longyu Zhou , Xingqin Lin , Yuchen Liu

Pathology image classification plays a crucial role in accurate medical diagnosis and treatment planning. Training high-performance models for this task typically requires large-scale annotated datasets, which are both expensive and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Lanfeng Zhong , Xin Liao , Shichuan Zhang , Shaoting Zhang , Guotai Wang

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Continual learning offers…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Artificial intelligence (AI) has significantly improved medical screening accuracy, particularly in cancer detection and risk assessment. However, traditional classification metrics often fail to account for imbalanced data, varying…

Machine Learning · Computer Science 2025-10-28 Longfei Wei , Fang Sheng , Jianfei Zhang

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Foundation models have emerged as a powerful tool for many AI problems. Despite the tremendous success of foundation models, effective adaptation to new tasks, particularly those with limited labels, remains an open question and lacks…

Machine Learning · Computer Science 2024-02-26 Zhuoyan Xu , Zhenmei Shi , Junyi Wei , Fangzhou Mu , Yin Li , Yingyu Liang

The development of computational pathology lies in the consensus that pathological characteristics of tumors are significant guidance for cancer diagnostics. Most existing research focuses on the inner-contextual information within each WSI…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Jun Shi , Tong Shu , Zhiguo Jiang , Wei Wang , Haibo Wu , Yushan Zheng

Recently, foundation models trained on massive datasets to adapt to a wide range of tasks have attracted considerable attention and are actively being explored within the computer vision community. Among these, the Segment Anything Model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Hyung-Il Kim , Kimin Yun , Jun-Seok Yun , Yuseok Bae

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Vision-language foundation models have shown great promise in computational pathology but remain primarily data-driven, lacking explicit integration of medical knowledge. We introduce KEEP (KnowledgE-Enhanced Pathology), a foundation model…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Xiao Zhou , Luoyi Sun , Dexuan He , Wenbin Guan , Ge Wang , Ruifen Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Ya Zhang , Kun Sun , Yanfeng Wang , Weidi Xie

Recent breakthroughs in generative simulation have harnessed Large Language Models (LLMs) to generate diverse robotic task curricula, yet these open-loop paradigms frequently produce linguistically coherent but physically infeasible goals,…

Robotics · Computer Science 2026-03-03 Bingchuan Wei , Bingqi Huang , Jingheng Ma , Zeyu zhang , Sen Cui

Performance of convolutional neural networks (CNNs) in image analysis tasks is often marred in the presence of acquisition-related distribution shifts between training and test images. Recently, it has been proposed to tackle this problem…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Neerav Karani , Georg Brunner , Ertunc Erdil , Simin Fei , Kerem Tezcan , Krishna Chaitanya , Ender Konukoglu

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

Prompt tuning, which involves training a small set of parameters, effectively enhances the pre-trained Vision-Language Models (VLMs) to downstream tasks. However, they often come at the cost of flexibility and adaptability when the tuned…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Mushui Liu , Bozheng Li , Yunlong Yu

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

Recent advancements in digital pathology have led to the development of numerous foundational models that utilize self-supervised learning on patches extracted from gigapixel whole slide images (WSIs). While this approach leverages vast…

Machine Learning · Computer Science 2024-08-23 Juseung Yun , Yi Hu , Jinhyung Kim , Jongseong Jang , Soonyoung Lee