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Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…
Semi monolithic detector designs with a series of stacked thin monolithic scintillator plates and side readout are an attractive approach for potentially achieving very high performance in a positron emission tomography (PET) scanner. In…
Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…
Positron Emission Tomography (PET) is a widely-used imaging modality for medical research and clinical diagnosis. Here we demonstrate, through detailed experiments and simulations, an exploration of the benefits of exploiting the quantum…
Positron emission tomography (PET) serves as an essential tool for diagnosis of encephalopathy and brain science research. However, it suffers from the limited choice of tracers. Nowadays, with the wide application of PET imaging in…
PETALO (Positron Emission TOF Apparatus based on Liquid xenOn) exploits the unique characteristics of liquid xenon as a scintillator for use in a PET detector. Here initial simulation studies are detailed which highlight the potential of…
Despite its tremendous value for the diagnosis, treatment monitoring and surveillance of children with cancer, whole body staging with positron emission tomography (PET) is time consuming and associated with considerable radiation exposure.…
Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…
Time-of-flight positron emission tomography (TOF-PET) detectors exhibiting multiple coincidence time resolution (CTR) components, such as those induced by the mixing of Cherenkov and scintillation photons, have attracted increasing…
Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…
In the present ongoing study, we are proposing a prototype model for positron emission tomography detection technology by introduction of a new discriminatory window parameter. It can be a new generation PET detection technique. We…
New detector approaches in Positron Emission Tomography imaging will play an important role in reducing costs, lowering administered radiation doses, and improving overall performance. PETALO employs liquid xenon as the active scintillating…
Novel Positron Emission Tomography system, based on plastic scintillators, is developed by the J-PET collaboration. In order to optimize geometrical configuration of built device, advanced computer simulations are performed. Detailed study…
Scattered coincidences introduce quantitative bias in positron emission tomography (PET) and must be compensated during reconstruction. Conventional scatter estimates typically rely on simplified cylindrical scanner models that omit…
Study of the uniformity of gain, energy resolution and count rate over active area of a triple GEM detector has been performed using a strong Fe55 X-ray source with premixed gas of Argon and CO2 in 70/30 ratio and conventional NIM…
Transforming the resistive plate chambers from charged-particle into gamma-quanta detectors opens the way towards their application as a basic element of a hybrid imaging system, which combines positron emission tomography (PET) with…
This study focuses on developing a self-triggered data acquisition system and a noise reduction algorithm for the Multi-gap Resistive Plate Chamber (MRPC) Time-of-Flight Positron Emission Tomography (TOF-PET) system. The system integrates a…
PETALO (Positron Emission Tof Apparatus with Liquid xenOn) is a novel concept for positron emission tomography scanners, which uses liquid xenon as a scintillation medium and silicon photomultipliers as a readout. The large scintillation…
Positronium Lifetime Imaging (PLI) extends positron emission tomography by using the lifetime of positronium atoms as a probe of tissue molecular architecture. In this work, we report the first PLI measurements performed with $^{52}$Mn and…
The Gas Electron Multiplier (GEM) detectors are widely used in high-energy physics (HEP) experiments as tracking devices because of their excellent position resolution and to handle high particle rates capability. Charging-up effect is a…