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RNA is a vital biomolecule with numerous roles and functions within cells, and interest in targeting it for therapeutic purposes has grown significantly in recent years. However, fully understanding and predicting RNA behavior, particularly…

The Bidirectional Encoder Representations from Transformers (BERT) were proposed in the natural language process (NLP) and shows promising results. Recently researchers applied the BERT to source-code representation learning and reported…

Computation and Language · Computer Science 2023-08-14 Lan Zhang , Chen Cao , Zhilong Wang , Peng Liu

Recognizing spans of biomedical concepts and their types (e.g., drug or gene) in free text, often called biomedical named entity recognition (NER), is a basic component of information extraction (IE) pipelines. Without a strong NER…

Computation and Language · Computer Science 2025-04-02 Motasem S Obeidat , Md Sultan Al Nahian , Ramakanth Kavuluru

Models based on bidirectional encoder representations from transformers (BERT) produce state of the art (SOTA) results on many natural language processing (NLP) tasks such as named entity recognition (NER), part-of-speech (POS) tagging etc.…

Computation and Language · Computer Science 2023-07-25 Shubham Vatsal , Adam Meyers , John E. Ortega

Language is an outcome of our complex and dynamic human-interactions and the technique of natural language processing (NLP) is hence built on human linguistic activities. Bidirectional Encoder Representations from Transformers (BERT) has…

Computation and Language · Computer Science 2022-12-06 Katsuma Inoue , Soh Ohara , Yasuo Kuniyoshi , Kohei Nakajima

Large language models (LLMs) trained on text demonstrated remarkable results on natural language processing (NLP) tasks. These models have been adapted to decipher the language of DNA, where sequences of nucleotides act as "words" that…

RNAs are essential molecules that carry genetic information vital for life, with profound implications for drug development and biotechnology. Despite this importance, RNA research is often hindered by the vast literature available on the…

Genomics · Quantitative Biology 2024-11-15 Yijia Xiao , Edward Sun , Yiqiao Jin , Wei Wang

Pre-trained contextual representations (e.g., BERT) have become the foundation to achieve state-of-the-art results on many NLP tasks. However, large-scale pre-training is computationally expensive. ELECTRA, an early attempt to accelerate…

Computation and Language · Computer Science 2020-06-17 Zhenhui Xu , Linyuan Gong , Guolin Ke , Di He , Shuxin Zheng , Liwei Wang , Jiang Bian , Tie-Yan Liu

The subcellular localization of RNAs, including long non-coding RNAs (lncRNAs), messenger RNAs (mRNAs), microRNAs (miRNAs) and other smaller RNAs, plays a critical role in determining their biological functions. For instance, lncRNAs are…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Cece Zhang , Xuehuan Zhu , Nick Peterson , Jieqiong Wang , Shibiao Wan

Large scale self-supervised pre-training of Transformer language models has advanced the field of Natural Language Processing and shown promise in cross-application to the biological `languages' of proteins and DNA. Learning effective…

Machine Learning · Computer Science 2021-12-15 Meredith V. Trotter , Cuong Q. Nguyen , Stephen Young , Rob T. Woodruff , Kim M. Branson

Since automatic translations can contain errors that require substantial human post-editing, machine translation proofreading is essential for improving quality. This paper proposes a novel hybrid approach for robust proofreading that…

Computation and Language · Computer Science 2025-06-06 Feijun Liu , Huifeng Wang , Kun Wang , Yizhen Wang

Functional or non-coding RNAs are attracting more attention as they are now potentially considered valuable resources in the development of new drugs intended to cure several human diseases. The identification of drugs targeting the…

Genomics · Quantitative Biology 2019-12-25 Muhammad Nabeel Asima , Muhammad Imran Malik , Andreas Dengela , Sheraz Ahmed

Natural Language Processing (NLP) has witnessed a transformative leap with the advent of transformer-based architectures, which have significantly enhanced the ability of machines to understand and generate human-like text. This paper…

Computation and Language · Computer Science 2025-03-27 Tianhao Wu , Yu Wang , Ngoc Quach

We introduce a new language representation model called BERT, which stands for Bidirectional Encoder Representations from Transformers. Unlike recent language representation models, BERT is designed to pre-train deep bidirectional…

Computation and Language · Computer Science 2019-05-28 Jacob Devlin , Ming-Wei Chang , Kenton Lee , Kristina Toutanova

Pre-training large language models on genomic sequences is a powerful approach for learning biologically meaningful representations. Masked language modeling (MLM) methods, such as DNABERT and Nucleotide Transformer (NT), achieve strong…

Genomics · Quantitative Biology 2025-08-20 Ke Ding , Brian Parker , Jiayu Wen

Transformer-based models, specifically BERT, have propelled research in various NLP tasks. However, these models are limited to a maximum token limit of 512 tokens. Consequently, this makes it non-trivial to apply it in a practical setting…

Computation and Language · Computer Science 2023-11-01 Aman Jaiswal , Evangelos Milios

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

The exponential growth of online textual content across diverse domains has necessitated advanced methods for automated text classification. Large Language Models (LLMs) based on transformer architectures have shown significant success in…

Computation and Language · Computer Science 2025-09-09 Zhyar Rzgar K Rostam , Gábor Kertész

Recently, pretrained language models based on BERT have been introduced for the French biomedical domain. Although these models have achieved state-of-the-art results on biomedical and clinical NLP tasks, they are constrained by a limited…

Computation and Language · Computer Science 2024-02-27 Adrien Bazoge , Emmanuel Morin , Beatrice Daille , Pierre-Antoine Gourraud

Bidirectional Encoder Representations from Transformers (BERT) has recently achieved state-of-the-art performance on a broad range of NLP tasks including sentence classification, machine translation, and question answering. The BERT model…

Computation and Language · Computer Science 2020-03-17 Zhiheng Huang , Peng Xu , Davis Liang , Ajay Mishra , Bing Xiang