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The Segment Anything Model (SAM) has recently demonstrated significant potential in medical image segmentation. Although SAM is primarily trained on 2D images, attempts have been made to apply it to 3D medical image segmentation. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Fangda Chen , Jintao Tang , Pancheng Wang , Ting Wang , Shasha Li , Ting Deng

Is Segment Anything Model 3 (SAM3) capable in segmenting Any Pathology Images? Digital pathology segmentation spans tissue-level and nuclei-level scales, where traditional methods often suffer from high annotation costs and poor…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Qiuyu Kong , Shakiba Sharifi , Yiming Wang , Marco Cristani , Zanxi Ruan

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Whole-body PET/CT is a cornerstone of oncological imaging, yet accurate lesion segmentation remains challenging due to tracer heterogeneity, physiological uptake, and multi-center variability. While fully automated methods have advanced…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Maximilian Rokuss , Yannick Kirchhoff , Fabian Isensee , Klaus H. Maier-Hein

The emergence of Segment Anything (SAM) sparked research interest in the field of interactive segmentation, especially in the context of image editing tasks and speeding up data annotation. Unlike common semantic segmentation, interactive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Anton Antonov , Andrey Moskalenko , Denis Shepelev , Alexander Krapukhin , Konstantin Soshin , Anton Konushin , Vlad Shakhuro

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…

The Segment Anything Model (SAM), originally built on a 2D Vision Transformer (ViT), excels at capturing global patterns in 2D natural images but struggles with 3D medical imaging modalities like CT and MRI. These modalities require…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xiang Gao , Kai Lu

Promptable Foundation Models (FMs), initially introduced for natural image segmentation, have also revolutionized medical image segmentation. The increasing number of models, along with evaluations varying in datasets, metrics, and compared…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Caroline Magg , Maaike A. ter Wee , Johannes G. G. Dobbe , Geert J. Streekstra , Leendert Blankevoort , Clara I. Sánchez , Hoel Kervadec

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

The Segment Anything Model (SAM) has demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) claims to outperform SAM on images and extends the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Sourya Sengupta , Satrajit Chakrabarty , Ravi Soni

Many deep learning based automated medical image segmentation systems, in reality, face difficulties in deployment due to the cost of massive data annotation and high latency in model iteration. We propose a dynamic interactive learning…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Mu Tian , Xiaohui Chen , Yi Gao

Since the release of Segment Anything 2 (SAM2), the medical imaging community has been actively evaluating its performance for 3D medical image segmentation. However, different studies have employed varying evaluation pipelines, resulting…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Yufan He , Pengfei Guo , Yucheng Tang , Andriy Myronenko , Vishwesh Nath , Ziyue Xu , Dong Yang , Can Zhao , Daguang Xu , Wenqi Li

Interactive segmentation model leverages prompts from users to produce robust segmentation. This advancement is facilitated by prompt engineering, where interactive prompts serve as strong priors during test-time. However, this is an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

The recent Segment Anything Models (SAMs) have emerged as foundational visual models for general interactive segmentation. Despite demonstrating robust generalization abilities, they still suffer performance degradations in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuan Yao , Qiushi Yang , Miaomiao Cui , Liefeng Bo

Interactive segmentation is a crucial research area in medical image analysis aiming to boost the efficiency of costly annotations by incorporating human feedback. This feedback takes the form of clicks, scribbles, or masks and allows for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Zdravko Marinov , Paul F. Jäger , Jan Egger , Jens Kleesiek , Rainer Stiefelhagen

Medical image and video segmentation is a critical task for precision medicine, which has witnessed considerable progress in developing task or modality-specific and generalist models for 2D images. However, there have been limited studies…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Jun Ma , Zongxin Yang , Sumin Kim , Bihui Chen , Mohammed Baharoon , Adibvafa Fallahpour , Reza Asakereh , Hongwei Lyu , Bo Wang

The Segment Anything Model (SAM) has revolutionized interactive segmentation through spatial prompting. While existing work primarily focuses on automating prompts in various settings, real-world annotation workflows involve iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib

Accurate segmentation of anatomical structures in volumetric medical images is crucial for clinical applications, including disease monitoring and cancer treatment planning. Contemporary interactive segmentation models, such as Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Tatyana Shmykova , Leila Khaertdinova , Ilya Pershin

Foundation models for volumetric medical image segmentation have emerged as powerful tools in clinical workflows, enabling radiologists to delineate regions of interest through intuitive clicks. While these models demonstrate promising…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Yifan Gao , Jiaxi Sheng , Wenbin Wu , Haoyue Li , Yaoxian Dong , Chaoyang Ge , Feng Yuan , Xin Gao