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Large language models (LLMs) have significantly transformed natural language understanding and generation, but they raise privacy concerns due to potential exposure of sensitive information. Studies have highlighted the risk of information…

Machine Learning · Computer Science 2025-11-20 Bishnu Bhusal , Manoj Acharya , Ramneet Kaur , Colin Samplawski , Anirban Roy , Adam D. Cobb , Rohit Chadha , Susmit Jha

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

Large Language Models (LLMs) are gaining increasing attention due to their exceptional performance across numerous tasks. As a result, the general public utilize them as an influential tool for boosting their productivity while natural…

Cryptography and Security · Computer Science 2023-06-16 Zhigang Kan , Linbo Qiao , Hao Yu , Liwen Peng , Yifu Gao , Dongsheng Li

The increasing use of synthetic data generated by Large Language Models (LLMs) presents both opportunities and challenges in data-driven applications. While synthetic data provides a cost-effective, scalable alternative to real-world data…

Computation and Language · Computer Science 2025-07-25 Tevin Atwal , Chan Nam Tieu , Yefeng Yuan , Zhan Shi , Yuhong Liu , Liang Cheng

Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing…

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

Computation and Language · Computer Science 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu

Large language models (LLMs) demonstrate remarkable medical expertise, but data privacy concerns impede their direct use in healthcare environments. Although offering improved data privacy protection, domain-specific small language models…

Computation and Language · Computer Science 2024-05-17 Xinlu Zhang , Shiyang Li , Xianjun Yang , Chenxin Tian , Yao Qin , Linda Ruth Petzold

An increasing number of companies have begun providing services that leverage cloud-based large language models (LLMs), such as ChatGPT. However, this development raises substantial privacy concerns, as users' prompts are transmitted to and…

Cryptography and Security · Computer Science 2025-02-24 Shilong Hou , Ruilin Shang , Zi Long , Xianghua Fu , Yin Chen

Synthetic data generation with Large Language Models (LLMs) has emerged as a promising solution in the medical domain to mitigate data scarcity and privacy constraints. However, existing approaches remain constrained by their derivative…

Artificial Intelligence · Computer Science 2026-01-07 Yunghwei Lai , Ziyue Wang , Weizhi Ma , Yang Liu

Conversational agents are increasingly woven into individuals' personal lives, yet users often underestimate the privacy risks associated with them. The moment users share information with these agents-such as large language models…

Cryptography and Security · Computer Science 2025-07-29 Ivoline Ngong , Swanand Kadhe , Hao Wang , Keerthiram Murugesan , Justin D. Weisz , Amit Dhurandhar , Karthikeyan Natesan Ramamurthy

Recently, powerful Large Language Models (LLMs) have become easily accessible to hundreds of millions of users world-wide. However, their strong capabilities and vast world knowledge do not come without associated privacy risks. In this…

Machine Learning · Computer Science 2024-11-05 Hanna Yukhymenko , Robin Staab , Mark Vero , Martin Vechev

The development of AI for mental health is hindered by a lack of authentic therapy dialogues, due to strict privacy regulations and the fact that clinical sessions were historically rarely recorded. We present an LLM-driven pipeline that…

Medical dialogue systems (MDS) enhance patient-physician communication, improve healthcare accessibility, and reduce costs. However, acquiring suitable data to train these systems poses significant challenges. Privacy concerns prevent the…

Computation and Language · Computer Science 2024-08-13 Trisha Das , Dina Albassam , Jimeng Sun

Artificial Intelligence-Generated Content, a subset of Generative Artificial Intelligence, holds significant potential for advancing the e-health sector by generating diverse forms of data. In this paper, we propose an end-to-end…

Machine Learning · Computer Science 2025-01-29 Tasnim Ahmed , Salimur Choudhury

Physician-physician discussions of patient cases represent a rich source of clinical knowledge and reasoning that could feed AI agents to enrich and even participate in subsequent interactions. However, privacy regulations and ethical…

Computation and Language · Computer Science 2026-04-13 Beny Rubinstein , Sergio Matos

The success of large language models (LLMs) facilitate many parties to fine-tune LLMs on their own private data. However, this practice raises privacy concerns due to the memorization of LLMs. Existing solutions, such as utilizing synthetic…

Cryptography and Security · Computer Science 2024-10-11 Wenhao Wang , Xiaoyu Liang , Rui Ye , Jingyi Chai , Siheng Chen , Yanfeng Wang

Large language models (LLMs) have demonstrated exceptional capabilities in text understanding and generation, and they are increasingly being utilized across various domains to enhance productivity. However, due to the high costs of…

Cryptography and Security · Computer Science 2024-11-05 Yu Mao , Xueping Liao , Wei Liu , Anjia Yang

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic,…

Artificial Intelligence · Computer Science 2025-08-13 Arshia Ilaty , Hossein Shirazi , Hajar Homayouni

Generating clinical synthetic text represents an effective solution for common clinical NLP issues like sparsity and privacy. This paper aims to conduct a systematic review on generating synthetic medical free-text by formulating…

Computation and Language · Computer Science 2025-07-25 Basel Alshaikhdeeb , Ahmed Abdelmonem Hemedan , Soumyabrata Ghosh , Irina Balaur , Venkata Satagopam
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