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Deep learning representations are often difficult to interpret, which can hinder their deployment in sensitive applications. Concept Bottleneck Models (CBMs) have emerged as a promising approach to mitigate this issue by learning…

Machine Learning · Computer Science 2026-01-30 Antonio Almudévar , José Miguel Hernández-Lobato , Alfonso Ortega

Black-box deep neural networks excel in text classification, yet their application in high-stakes domains is hindered by their lack of interpretability. To address this, we propose Text Bottleneck Models (TBM), an intrinsically…

Computation and Language · Computer Science 2024-04-04 Josh Magnus Ludan , Qing Lyu , Yue Yang , Liam Dugan , Mark Yatskar , Chris Callison-Burch

Deep learning has advanced NLP, but interpretability remains limited, especially in healthcare and finance. Concept bottleneck models tie predictions to human concepts in vision, but NLP versions either use binary activations that harm text…

Computation and Language · Computer Science 2026-03-31 Yibo Yang

Concept Bottleneck Models (CBMs) promote interpretability by grounding predictions in human-understandable concepts. However, existing CBMs typically fix their task predictor to a single linear or Boolean expression, limiting both…

The main challenges limiting the adoption of deep learning-based solutions in medical workflows are the availability of annotated data and the lack of interpretability of such systems. Concept Bottleneck Models (CBMs) tackle the latter by…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Cristiano Patrício , Isabel Rio-Torto , Jaime S. Cardoso , Luís F. Teixeira , João C. Neves

Concept bottleneck models (CBMs) are interpretable neural networks that first predict labels for human-interpretable concepts relevant to the prediction task, and then predict the final label based on the concept label predictions. We…

Machine Learning · Computer Science 2023-04-28 Kushal Chauhan , Rishabh Tiwari , Jan Freyberg , Pradeep Shenoy , Krishnamurthy Dvijotham

The concept bottleneck model (CBM), as a technique improving interpretability via linking predictions to human-understandable concepts, makes high-risk and life-critical medical image classification credible. Typically, existing CBM methods…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Chunjiang Wang , Kun Zhang , Yandong Liu , Zhiyang He , Xiaodong Tao , S. Kevin Zhou

Concept Bottleneck Models (CBMs) are interpretable models that route predictions through a layer of human-interpretable concepts. While widely studied in vision and, more recently, in NLP, CBMs remain largely unexplored in multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Pierre Moreau , Emeline Pineau Ferrand , Yann Choho , Benjamin Wong , Annabelle Blangero , Milan Bhan

Concept Bottleneck Models (CBMs) have garnered much attention for their ability to elucidate the prediction process through a humanunderstandable concept layer. However, most previous studies focused on cases where the data, including…

Machine Learning · Computer Science 2025-02-04 Lijie Hu , Chenyang Ren , Zhengyu Hu , Hongbin Lin , Cheng-Long Wang , Hui Xiong , Jingfeng Zhang , Di Wang

Concept Bottleneck Models (CBMs) map the inputs onto a set of interpretable concepts (``the bottleneck'') and use the concepts to make predictions. A concept bottleneck enhances interpretability since it can be investigated to understand…

Machine Learning · Computer Science 2023-02-03 Mert Yuksekgonul , Maggie Wang , James Zou

The design of interpretable deep learning models working in relational domains poses an open challenge: interpretable deep learning methods, such as Concept Bottleneck Models (CBMs), are not designed to solve relational problems, while…

Machine Learning · Computer Science 2024-10-28 Pietro Barbiero , Francesco Giannini , Gabriele Ciravegna , Michelangelo Diligenti , Giuseppe Marra

The opaque nature of Large Language Models (LLMs) has led to significant research efforts aimed at enhancing their interpretability, primarily through post-hoc methods. More recent in-hoc approaches, such as Concept Bottleneck Models…

Machine Learning · Computer Science 2025-02-20 Or Raphael Bidusa , Shaul Markovitch

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

We propose an automated genomic interpretation module that transforms raw DNA sequences into actionable, interpretable decisions suitable for integration into medical automation and robotic systems. Our framework combines Chaos Game…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zijun Li , Jinchang Zhang , Ming Zhang , Guoyu Lu

The lack of transparency in the decision-making processes of deep learning systems presents a significant challenge in modern artificial intelligence (AI), as it impairs users' ability to rely on and verify these systems. To address this…

Artificial Intelligence · Computer Science 2024-11-18 David Debot , Pietro Barbiero , Francesco Giannini , Gabriele Ciravegna , Michelangelo Diligenti , Giuseppe Marra

Concept Bottleneck Models (CBMs) have emerged as a prominent paradigm for interpretable deep learning, learning by grounding predictions in human-understandable concepts. However, their practical deployment is hindered by the high cost of…

Machine Learning · Computer Science 2026-05-29 Ziye Chen , Hongbin Lin , Jie Li , Lijie Hu

Language Bottleneck Models (LBMs) are proposed to achieve interpretable image recognition by classifying images based on textual concept bottlenecks. However, current LBMs simply list all concepts together as the bottleneck layer, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Jianyang Zhang , Qianli Luo , Guowu Yang , Wenjing Yang , Weide Liu , Guosheng Lin , Fengmao Lv

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Concept Bottleneck Models (CBMs) introduce interpretability to black-box deep learning models by predicting labels through human-understandable concepts. However, unlike humans, who identify objects at different levels of abstraction using…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Haodong Xie , Yujun Cai , Rahul Singh Maharjan , Yiwei Wang , Federico Tavella , Angelo Cangelosi

Despite their success, Large-Language Models (LLMs) still face criticism due to their lack of interpretability. Traditional post-hoc interpretation methods, based on attention and gradient-based analysis, offer limited insights as they only…

Computation and Language · Computer Science 2025-07-17 Francesco De Santis , Philippe Bich , Gabriele Ciravegna , Pietro Barbiero , Danilo Giordano , Tania Cerquitelli