English
Related papers

Related papers: Integrating Large Language Models for Genetic Vari…

200 papers

Since the inception of the Transformer architecture in 2017, Large Language Models (LLMs) such as GPT and BERT have evolved significantly, impacting various industries with their advanced capabilities in language understanding and…

Computation and Language · Computer Science 2024-05-30 Yining Huang , Keke Tang , Meilian Chen , Boyuan Wang

Digital twin technology is a transformative innovation driving the digital transformation and intelligent optimization of manufacturing systems. By integrating real-time data with computational models, digital twins enable continuous…

Emerging Technologies · Computer Science 2025-03-05 Linyao Yang , Shi Luo , Xi Cheng , Lei Yu

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

The application of large language models (LLMs) to healthcare information extraction has emerged as a promising approach. This study evaluates the classification performance of five open-source LLMs: GEMMA-3-27B-IT, LLAMA3-70B, LLAMA4-109B,…

Computation and Language · Computer Science 2025-05-09 Yuting Guo , Abeed Sarker

Predicting protein stability changes induced by single-point mutations has been a persistent challenge over the years, attracting immense interest from numerous researchers. The ability to precisely predict protein thermostability is…

Biomolecules · Quantitative Biology 2023-12-08 Yijie Zhang , Zhangyang Gao , Cheng Tan , Stan Z. Li

The integration of large language models (LLMs) into automated algorithm design has shown promising potential. A prevalent approach embeds LLMs within search routines to iteratively generate and refine candidate algorithms. However, most…

Machine Learning · Computer Science 2026-05-20 Fei Liu , Rui Zhang , Xi Lin , Zhichao Lu , Qingfu Zhang

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

Large language models (LLMs) are effective at capturing complex, valuable conceptual representations from textual data for a wide range of real-world applications. However, in fields like Intelligent Fault Diagnosis (IFD), incorporating…

Artificial Intelligence · Computer Science 2024-12-03 Hamzah A. A. M. Qaid , Bo Zhang , Dan Li , See-Kiong Ng , Wei Li

The integration of Large Language Models (LLMs) with Graph Representation Learning (GRL) marks a significant evolution in analyzing complex data structures. This collaboration harnesses the sophisticated linguistic capabilities of LLMs to…

Machine Learning · Computer Science 2024-02-12 Qiheng Mao , Zemin Liu , Chenghao Liu , Zhuo Li , Jianling Sun

The healthcare industry is currently experiencing an unprecedented wave of cybersecurity attacks, impacting millions of individuals. With the discovery of thousands of vulnerabilities each month, there is a pressing need to drive the…

Computation and Language · Computer Science 2024-07-23 Rikhiya Ghosh , Oladimeji Farri , Hans-Martin von Stockhausen , Martin Schmitt , George Marica Vasile

Recent advancements in AI have reinvigorated Agent-Based Models (ABMs), as the integration of Large Language Models (LLMs) has led to the emergence of ``generative ABMs'' as a novel approach to simulating social systems. While ABMs offer…

Multiagent Systems · Computer Science 2025-04-07 Maik Larooij , Petter Törnberg

Despite various approaches being employed to detect vulnerabilities, the number of reported vulnerabilities shows an upward trend over the years. This suggests the problems are not caught before the code is released, which could be caused…

Cryptography and Security · Computer Science 2025-02-14 Karl Tamberg , Hayretdin Bahsi

This paper provides a comprehensive review of the integration of Large Language Models (LLMs) with visual analytics, addressing their foundational concepts, capabilities, and wide-ranging applications. It begins by outlining the theoretical…

Human-Computer Interaction · Computer Science 2025-03-20 Navya Sonal Agarwal , Sanjay Kumar Sonbhadra

Distilling underlying principles from data has historically driven scientific breakthroughs. However, conventional data-driven machine learning often produces complex models that lack interpretability and generalization due to insufficient…

Materials Science · Physics 2025-07-28 Zhilong Song , Qionghua Zhou , Chunjin Ren , Chongyi Ling , Minggang Ju , Jinlan Wang

Virtual screening plays a critical role in modern drug discovery by enabling the identification of promising candidate molecules for experimental validation. Traditional machine learning methods such, as Support Vector Machines (SVM) and…

Machine Learning · Computer Science 2025-04-29 Radia Berreziga , Mohammed Brahimi , Khairedine Kraim , Hamid Azzoune

Large language models (LLMs) have recently achieved significant success across various application domains, garnering substantial attention from different communities. Unfortunately, even for the best LLM, many \textit{faults} still exist…

Software Engineering · Computer Science 2024-11-06 Qiang Hu , Jin Wen , Maxime Cordy , Yuheng Huang , Wei Ma , Xiaofei Xie , Lei Ma

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…