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The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

Novel deep learning architectures are increasingly being applied to biological data, including genetic sequences. These models, referred to as genomic language models (gLMs), have demonstrated impressive predictive and generative…

Machine Learning · Computer Science 2026-03-24 James R. M. Black , Moritz S. Hanke , Aaron Maiwald , Tina Hernandez-Boussard , Oliver M. Crook , Jaspreet Pannu

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

Recently, the intersection of Large Language Models (LLMs) and Computer Vision (CV) has emerged as a pivotal area of research, driving significant advancements in the field of Artificial Intelligence (AI). As transformers have become the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Raby Hamadi

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Research on long non-coding RNAs (lncRNAs) has garnered significant attention due to their critical roles in gene regulation and disease mechanisms. However, the complexity and diversity of lncRNA sequences, along with the limited knowledge…

Genomics · Quantitative Biology 2024-11-07 Wei Wang , Zhichao Hou , Xiaorui Liu , Xinxia Peng

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

In recent years, Large Language Models (LLMs) have become fundamental to a broad spectrum of artificial intelligence applications. As the use of LLMs expands, precisely estimating the uncertainty in their predictions has become crucial.…

Artificial Intelligence · Computer Science 2024-10-29 Mohammad Beigi , Sijia Wang , Ying Shen , Zihao Lin , Adithya Kulkarni , Jianfeng He , Feng Chen , Ming Jin , Jin-Hee Cho , Dawei Zhou , Chang-Tien Lu , Lifu Huang

In recent times, Vision-Language Models (VLMs) have been trained under two predominant paradigms. Generative training has enabled Multimodal Large Language Models (MLLMs) to tackle various complex tasks, yet issues such as hallucinations…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Wei Chow , Juncheng Li , Qifan Yu , Kaihang Pan , Hao Fei , Zhiqi Ge , Shuai Yang , Siliang Tang , Hanwang Zhang , Qianru Sun

Large Language Models (LLMs) have demonstrated remarkable capabilities across various applications, fundamentally reshaping the landscape of natural language processing (NLP) research. However, recent evaluation frameworks often rely on the…

Computation and Language · Computer Science 2024-07-10 Chenyang Lyu , Minghao Wu , Alham Fikri Aji

Visual Language Models (VLMs) are now increasingly being merged with Large Language Models (LLMs) to enable new capabilities, particularly in terms of improved interactivity and open-ended responsiveness. While these are remarkable…

Biomedical research requires large, diverse samples to produce unbiased results. Automated methods for matching variables across datasets can accelerate this process. Research in this area has been limited, primarily focusing on lexical…

Computation and Language · Computer Science 2024-11-06 Zexu Li , Suraj P. Prabhu , Zachary T. Popp , Shubhi S. Jain , Vijetha Balakundi , Ting Fang Alvin Ang , Rhoda Au , Jinying Chen

Large Vision-Language Models (LVLMs) are capable of handling diverse data types such as imaging, text, and physiological signals, and can be applied in various fields. In the medical field, LVLMs have a high potential to offer substantial…

This research introduces a transformative framework for integrating Vision-Enhanced Large Language Models (LLMs) with advanced transformer-based architectures to tackle challenges in high-resolution image synthesis and multimodal data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Karthikeya KV

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Large Language Models (LLMs) have introduced a new era of proficiency in comprehending complex healthcare and biomedical topics. However, there is a noticeable lack of models in languages other than English and models that can interpret…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Junling Liu , Ziming Wang , Qichen Ye , Dading Chong , Peilin Zhou , Yining Hua
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