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Large Language Models (LLMs) exhibit emerging in-context learning abilities through prompt engineering. The recent progress in large-scale generative models has further expanded their use in real-world language applications. However, the…

Computation and Language · Computer Science 2024-04-12 Linyi Yang , Shuibai Zhang , Zhuohao Yu , Guangsheng Bao , Yidong Wang , Jindong Wang , Ruochen Xu , Wei Ye , Xing Xie , Weizhu Chen , Yue Zhang

Large Language Models (LLMs) are starting to be profiled as one of the most significant disruptions in the Software Testing field. Specifically, they have been successfully applied in software testing tasks such as generating test code, or…

Software Engineering · Computer Science 2025-09-30 Cristian Augusto , Antonia Bertolino , Guglielmo De Angelis , Francesca Lonetti , Jesús Morán

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha

With the recent progress of Large Language Models (LLMs), there is a growing interest in applying these models to solve complex and challenging problems. Modern LLMs, capable of processing long contexts and generating verbalized…

Computation and Language · Computer Science 2026-04-14 WonJin Yoon , Kangyu Zhu , Ian Bulovic , Autumn Sehy , Yanjun Gao , Dmitriy Dligach , Majid Afshar , Timothy A. Miller

Large language models (LLMs) have substantially advanced machine learning research, including natural language processing, computer vision, data mining, etc., yet they still exhibit critical limitations in explainability, reliability,…

Machine Learning · Computer Science 2025-09-19 Xin Wang , Haoyang Li , Haibo Chen , Zeyang Zhang , Wenwu Zhu

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Recent advances in large language model (LLM) embeddings have enabled powerful representations for biological data, but most applications to date focus on gene-level information. We present one of the first systematic frameworks to generate…

Applications · Statistics 2026-04-01 Hongqian Niu , Jordan Bryan , Jacob Williams , Hufeng Zhou , Haoyu Zhang , Xihao Li , Didong Li

This paper explores the integration of Large Language Models (LLMs) into Automatic Speech Recognition (ASR) systems to improve transcription accuracy. The increasing sophistication of LLMs, with their in-context learning capabilities and…

Computation and Language · Computer Science 2025-06-03 Zeping Min , Jinbo Wang

Large language models (LLMs) have emerged as powerful tools with transformative potential across numerous domains, including healthcare and medicine. In the medical domain, LLMs hold promise for tasks ranging from clinical decision support…

Computation and Language · Computer Science 2024-05-14 Xiaolan Chen , Jiayang Xiang , Shanfu Lu , Yexin Liu , Mingguang He , Danli Shi

Unlocking the potential of Large Language Models (LLMs) in data classification represents a promising frontier in natural language processing. In this work, we evaluate the performance of different LLMs in comparison with state-of-the-art…

Computation and Language · Computer Science 2025-01-16 Arina Kostina , Marios D. Dikaiakos , Dimosthenis Stefanidis , George Pallis

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

Large language models (LLMs) exhibit probabilistic output characteristics, yet conventional evaluation frameworks rely on deterministic scalar metrics. This study introduces a Bayesian approach for LLM capability assessment that integrates…

Computation and Language · Computer Science 2025-05-01 Xiao Xiao , Yu Su , Sijing Zhang , Zhang Chen , Yadong Chen , Tian Liu

Unmanned Aerial Vehicles (UAVs) have emerged as a transformative technology across diverse sectors, offering adaptable solutions to complex challenges in both military and civilian domains. Their expanding capabilities present a platform…

Artificial Intelligence · Computer Science 2024-05-06 Shumaila Javaid , Nasir Saeed , Bin He

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

The rapid evolution of malware variants requires robust classification methods to enhance cybersecurity. While Large Language Models (LLMs) offer potential for generating malware descriptions to aid family classification, their utility is…

Cryptography and Security · Computer Science 2025-05-01 Ivan Montoya Sanchez , Shaswata Mitra , Aritran Piplai , Sudip Mittal

Genomic language models (gLMs) have shown mostly modest success in identifying evolutionarily constrained elements in mammalian genomes. To address this issue, we introduce a novel framework for training gLMs that explicitly models…

Genomics · Quantitative Biology 2026-03-23 Carlos Albors , Jianan Canal Li , Gonzalo Benegas , Chengzhong Ye , Yun S. Song

In the rapidly evolving domain of Natural Language Generation (NLG) evaluation, introducing Large Language Models (LLMs) has opened new avenues for assessing generated content quality, e.g., coherence, creativity, and context relevance.…

Computation and Language · Computer Science 2024-06-13 Zhen Li , Xiaohan Xu , Tao Shen , Can Xu , Jia-Chen Gu , Yuxuan Lai , Chongyang Tao , Shuai Ma

This systematic literature review comprehensively examines the application of Large Language Models (LLMs) in forecasting and anomaly detection, highlighting the current state of research, inherent challenges, and prospective future…

Machine Learning · Computer Science 2024-02-19 Jing Su , Chufeng Jiang , Xin Jin , Yuxin Qiao , Tingsong Xiao , Hongda Ma , Rong Wei , Zhi Jing , Jiajun Xu , Junhong Lin

Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches make very different assumptions, so are…

Quantitative Methods · Quantitative Biology 2012-11-16 Xiang Zhou , Peter Carbonetto , Matthew Stephens
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