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Omics data is widely employed in medical research to identify disease mechanisms and contains highly sensitive personal information. Federated Learning (FL) with Differential Privacy (DP) can ensure the protection of omics data privacy…

Cryptography and Security · Computer Science 2025-11-11 Yusaku Negoya , Feifei Cui , Zilong Zhang , Miao Pan , Tomoaki Ohtsuki , Aohan Li

Deep learning (DL) has been increasingly applied in medical imaging, however, it requires large amounts of data, which raises many challenges related to data privacy, storage, and transfer. Federated learning (FL) is a training paradigm…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Jan Fiszer , Dominika Ciupek , Maciej Malawski

Federated learning (FL) is gaining increasing popularity in the medical domain for analyzing medical images, which is considered an effective technique to safeguard sensitive patient data and comply with privacy regulations. However,…

Machine Learning · Computer Science 2024-02-01 Badhan Chandra Das , M. Hadi Amini , Yanzhao Wu

Lack of generalization to unseen domains/attacks is the Achilles heel of most face presentation attack detection (FacePAD) algorithms. Existing attempts to enhance the generalizability of FacePAD solutions assume that data from multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Naif Alkhunaizi , Koushik Srivatsan , Faris Almalik , Ibrahim Almakky , Karthik Nandakumar

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

Protecting sensitive health data while enabling collaborative analysis is a central challenge in healthcare. Traditional machine learning (ML) requires institutions to pool anonymized patient records, centralizing analytical development and…

Machine Learning · Computer Science 2026-05-05 Gaurang Sharma , Juha Pajula , Aada Illikainen , Markus Rautell , Noora Lipsonen , Petri Alhainen , Mika Hilvo

Due to medical data privacy regulations, it is often infeasible to collect and share patient data in a centralised data lake. This poses challenges for training machine learning algorithms, such as deep convolutional networks, which often…

Computer Vision and Pattern Recognition · Computer Science 2019-10-03 Wenqi Li , Fausto Milletarì , Daguang Xu , Nicola Rieke , Jonny Hancox , Wentao Zhu , Maximilian Baust , Yan Cheng , Sébastien Ourselin , M. Jorge Cardoso , Andrew Feng

In this paper, we propose a method for privacy-preserving federated learning that uses randomly selected model parameters to update global models. High-quality deep neural networks (DNN) models require a huge amount of training data in…

Cryptography and Security · Computer Science 2026-05-05 Hiroto Sawada , Shoko Imaizumi , Hitoshi Kiya

Federated learning (FL) is a decentralized method enabling hospitals to collaboratively learn a model without sharing private patient data for training. In FL, participant hospitals periodically exchange training results rather than…

Cryptography and Security · Computer Science 2022-08-24 S. Maryam Hosseini , Milad Sikaroudi , Morteza Babaei , H. R. Tizhoosh

Collaborative machine learning across healthcare institutions promises improved diagnostic accuracy by leveraging diverse datasets, yet privacy regulations such as HIPAA prohibit direct patient data sharing. While federated learning (FL)…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Al Amin , Kamrul Hasan , Liang Hong , Sharif Ullah

Federated learning (FL) is a distributed machine learning method where multiple devices collaboratively train a model under the management of a central server without sharing underlying data. One of the key challenges of FL is the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Emre Ardıç , Yakup Genç

Federated learning (FL) has attracted growing attention since it allows for privacy-preserving collaborative training on decentralized clients without explicitly uploading sensitive data to the central server. However, recent works have…

Machine Learning · Computer Science 2023-12-19 Yuting Ma , Yuanzhi Yao , Xiaohua Xu

Collaborative training across multiple institutions is becoming essential for building reliable medical image segmentation models. However, privacy regulations, data silos, and uneven data availability prevent hospitals from sharing raw…

Quantitative Methods · Quantitative Biology 2026-03-09 Saheed Ademola Bello , Muhammad Shahid Jabbar , Muhammad Sohail Ibrahim , Shujaat Khan

With the rapid digitalization of healthcare systems, there has been a substantial increase in the generation and sharing of private health data. Safeguarding patient information is essential for maintaining consumer trust and ensuring…

Artificial Intelligence · Computer Science 2026-01-27 Yazan Otoum , Amiya Nayak

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Machine learning in medical research, by nature, needs careful attention on obeying the regulations of data privacy, making it difficult to train a machine learning model over gathered data from different medical centers. Failure of…

Machine Learning · Computer Science 2021-10-19 Jun Luo , Shandong Wu

This study introduces a federated learning-based approach to predict HER2 status from hematoxylin and eosin (HE)-stained whole slide images (WSIs), reducing costs and speeding up treatment decisions. To address label imbalance and feature…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Kamorudeen A. Amuda , Almustapha A. Wakili

Machine learning (ML) and Artificial Intelligence (AI) have fueled remarkable advancements, particularly in healthcare. Within medical imaging, ML models hold the promise of improving disease diagnoses, treatment planning, and…

Machine Learning · Computer Science 2024-06-19 Nikolas Koutsoubis , Yasin Yilmaz , Ravi P. Ramachandran , Matthew Schabath , Ghulam Rasool

Federated learning allows distributed medical institutions to collaboratively learn a shared prediction model with privacy protection. While at clinical deployment, the models trained in federated learning can still suffer from performance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Quande Liu , Cheng Chen , Jing Qin , Qi Dou , Pheng-Ann Heng

Federated Learning (FL) is an emerging paradigm through which decentralized devices can collaboratively train a common model. However, a serious concern is the leakage of privacy from exchanged gradient information between clients and the…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-02 Wenzhuo Yang , Yipeng Zhou , Maio Hu , Di Wu , James Xi Zheng , Hui Wang , Song Guo