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Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

Federated Learning (FL) is a paradigm for large-scale distributed learning which faces two key challenges: (i) efficient training from highly heterogeneous user data, and (ii) protecting the privacy of participating users. In this work, we…

Machine Learning · Computer Science 2023-01-06 Maxence Noble , Aurélien Bellet , Aymeric Dieuleveut

Unsupervised image anomaly detection (UAD) has become a critical process in industrial and medical applications, but it faces growing challenges due to increasing concerns over data privacy. The limited class diversity inherent to one-class…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-30 Silin Chen , Andy Liu , Kangjian Di , Yichu Xu , Han-Jia Ye , Wenhan Luo , Ningmu Zou

The effective detection of evidence of financial anomalies requires collaboration among multiple entities who own a diverse set of data, such as a payment network system (PNS) and its partner banks. Trust among these financial institutions…

Differential privacy (DP) is a key technique for protecting sensitive patient data in medical deep learning (DL). As clinical models grow more data-dependent, balancing privacy with utility and fairness has become a critical challenge. This…

Objective: The exchange of health-related data is subject to regional laws and regulations, such as the General Data Protection Regulation (GDPR) in the EU or the Health Insurance Portability and Accountability Act (HIPAA) in the United…

Computers and Society · Computer Science 2024-01-24 Tom Bisson , Michael Franz , Isil Dogan O , Daniel Romberg , Christoph Jansen , Peter Hufnagl , Norman Zerbe

Data privacy constraints pose significant challenges for large-scale neuroimaging analysis, especially in multi-site functional magnetic resonance imaging (fMRI) studies, where site-specific heterogeneity leads to non-independent and…

Machine Learning · Computer Science 2025-09-26 Yipu Zhang , Chengshuo Zhang , Ziyu Zhou , Gang Qu , Hao Zheng , Yuping Wang , Hui Shen , Hongwen Deng

Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise…

Federated learning (FL) faces a critical dilemma: existing protection mechanisms like differential privacy (DP) and homomorphic encryption (HE) enforce a rigid trade-off, forcing a choice between model utility and computational efficiency.…

Machine Learning · Computer Science 2025-09-18 Zihou Wu , Yuecheng Li , Tianchi Liao , Jian Lou , Chuan Chen

Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Machine Learning (ML) algorithms are generally designed for scenarios in which all data is stored in one data center, where the training is performed. However, in many applications, e.g., in the healthcare domain, the training data is…

Machine Learning · Computer Science 2024-09-16 Amin Aminifar , Matin Shokri , Amir Aminifar

Recently, federated learning has raised increasing interest in the medical image analysis field due to its ability to aggregate multi-center data with privacy-preserving properties. A large amount of federated training schemes have been…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Matthis Manthe , Stefan Duffner , Carole Lartizien

Although data-driven methods usually have noticeable performance on disease diagnosis and treatment, they are suspected of leakage of privacy due to collecting data for model training. Recently, federated learning provides a secure and…

Artificial Intelligence · Computer Science 2023-06-27 Yawei Zhao , Qinghe Liu , Xinwang Liu , Kunlun He

Artificial intelligence (AI) has shown great potential in medical imaging, particularly for brain tumor detection using Magnetic Resonance Imaging (MRI). However, the models remain vulnerable at inference time when they are trained…

Machine Learning · Computer Science 2025-11-18 Mohammad Karami , Mohammad Reza Nemati , Aidin Kazemi , Ali Mikaeili Barzili , Hamid Azadegan , Behzad Moshiri

Transformer-based foundation models (FMs) have recently demonstrated remarkable performance in medical image segmentation. However, scaling these models is challenging due to the limited size of medical image datasets within isolated…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yumin Zhang , Yan Gao , Haoran Duan , Hanqing Guo , Tejal Shah , Rajiv Ranjan , Bo Wei

Globally, Skin carcinoma is among the most lethal diseases. Millions of people are diagnosed with this cancer every year. Sill, early detection can decrease the medication cost and mortality rate substantially. The recent improvement in…

Computer Vision and Pattern Recognition · Computer Science 2022-04-13 Tariq Bdair , Nassir Navab , Shadi Albarqouni

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Masoud Tafavvoghi , Anders Sildnes , Mehrdad Rakaee , Nikita Shvetsov , Lars Ailo Bongo , Lill-Tove Rasmussen Busund , Kajsa Møllersen

In the medical field, multi-center collaborations are often sought to yield more generalizable findings by leveraging the heterogeneity of patient and clinical data. However, recent privacy regulations hinder the possibility to share data,…

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