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The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Generating realistic synthetic electronic health records (EHRs) holds tremendous promise for accelerating healthcare research, facilitating AI model development and enhancing patient privacy. However, existing generative methods typically…

Machine Learning · Computer Science 2025-07-28 Guanglin Zhou , Sebastiano Barbieri

Synthetic Electronic Health Record (EHR) generation provides a promising avenue for data augmentation and cross-hospital modeling in privacy-constrained healthcare settings. However, most existing EHR generative models are centralized and…

Machine Learning · Computer Science 2026-05-28 Jun Bai , Ziyang Song , Yue Li

Electronic Health Records (EHRs) contain sensitive patient information, which presents privacy concerns when sharing such data. Synthetic data generation is a promising solution to mitigate these risks, often relying on deep generative…

Machine Learning · Computer Science 2023-08-11 Taha Ceritli , Ghadeer O. Ghosheh , Vinod Kumar Chauhan , Tingting Zhu , Andrew P. Creagh , David A. Clifton

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

There is no consensus in the field of synthetic data on concise metrics for quality evaluations or benchmarks on large health datasets, such as historical epidemiological data. This study presents an evaluation of seven recent models from…

Machine Learning · Computer Science 2026-04-20 Jean-Baptiste Escudié , Benjamin Barnes , Stefan Meisegeier , Klaus Kraywinkel , Fabian Prasser , Nils Körber

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

AI-based data synthesis has seen rapid progress over the last several years, and is increasingly recognized for its promise to enable privacy-respecting high-fidelity data sharing. However, adequately evaluating the quality of generated…

Machine Learning · Statistics 2021-04-02 Michael Platzer , Thomas Reutterer

The advancement of generative AI, particularly in medical imaging, confronts the trilemma of ensuring high fidelity, diversity, and efficiency in synthetic data generation. While Generative Adversarial Networks (GANs) have shown promise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lorenzo Tronchin , Tommy Löfstedt , Paolo Soda , Valerio Guarrasi

Synthetic electronic health records (EHRs) that are both realistic and preserve privacy can serve as an alternative to real EHRs for machine learning (ML) modeling and statistical analysis. However, generating high-fidelity and granular…

Machine Learning · Computer Science 2023-11-13 Brandon Theodorou , Cao Xiao , Jimeng Sun

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Synthetic datasets are important for evaluating and testing machine learning models. When evaluating real-life recommender systems, high-dimensional categorical (and sparse) datasets are often considered. Unfortunately, there are not many…

Information Retrieval · Computer Science 2024-12-11 Miha Malenšek , Blaž Škrlj , Blaž Mramor , Jure Demšar

The rapid advancements in generative AI and large language models (LLMs) have opened up new avenues for producing synthetic data, particularly in the realm of structured tabular formats, such as product reviews. Despite the potential…

Machine Learning · Computer Science 2025-07-25 Yefeng Yuan , Yuhong Liu , Liang Cheng

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Synthetic data generation offers promise for addressing data scarcity and privacy concerns in educational technology, yet practitioners lack empirical guidance for selecting between traditional resampling techniques and modern deep learning…

Machine Learning · Computer Science 2026-04-24 Tapiwa Amion Chinodakufa , Ashfaq Ali Shafin , Khandaker Mamun Ahmed

Generative modeling has been used frequently in synthetic data generation. Fairness and privacy are two big concerns for synthetic data. Although Recent GAN [\cite{goodfellow2014generative}] based methods show good results in preserving…

Machine Learning · Computer Science 2023-07-04 Weijie Xu , Jinjin Zhao , Francis Iannacci , Bo Wang

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets…

Machine Learning · Statistics 2018-07-05 Laura Aviñó , Matteo Ruffini , Ricard Gavaldà

The vast amount of available medical records has the potential to improve healthcare and biomedical research. However, privacy restrictions make these data accessible for internal use only. Recent works have addressed this problem by…

Computation and Language · Computer Science 2025-01-31 Samuel Belkadi , Libo Ren , Nicolo Micheletti , Lifeng Han , Goran Nenadic

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro