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There have been increased concerns that the use of statins, one of the most commonly prescribed drugs for treating coronary artery disease, is potentially associated with the increased risk of new-onset type II diabetes (T2D). Nevertheless,…
We consider a model of asexually reproducing individuals with random mutations and selection. The rate of mutations is proportional to the population size, $N$. The mutations may be either beneficial or deleterious. In a paper by Yu,…
Sex chromosomes have evolved repeatedly across the Tree of Life, yet their evolutionary fates differ strikingly. In sharp contrast to mammals and birds with degenerated, stable Y/W chromosomes, in most amphibians, teleosts, non avian…
Better understanding the molecular processes contributing to variation in maturation timing is important for Atlantic salmon aquaculture, as early maturation causes considerable financial losses. The m6A RNA methylation is a conserved and…
Despite increasing representation in graduate training programs, a disproportionate number of women leave academic research before obtaining an independent position. To understand factors underlying this trend, we analyzed a…
A single gene, regulating its own expression via a positive feedback loop, constitutes a common motif in gene regulatory networks and signalling cascades. Recent experiments on the development of competence in the bacterial population…
There were over 70,000 drug overdose deaths in the USA in 2017. Almost half of those involved the use of Opioids such as Heroin. This research supports efforts to combat the Opioid Epidemic by further understanding factors that lead to…
Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween…
Understanding the differentiation, a biological process from a multipotent stem or progenitor state to a mature cell is critically important. We develop a theoretical framework to quantify the underlying potential landscape and biological…
Prognostication of medical problems using the clinical data by leveraging the Machine Learning techniques with stellar precision is one of the most important real world challenges at the present time. Considering the medical problem of…
We study dynamic decentralized two-sided matching in which players may encounter unanticipated experiences. As they become aware of these experiences, they may change their preferences over players on the other side of the market.…
\noindent\textbf{Background} Prenatal glucocorticoid exposure alters cardiac development, but whether persistent cardiac effects in childhood follow a dose-response relationship remains unknown. We recently showed that ECG foundation models…
Test anxiety is beginning to be recognized as a significant factor affecting student performance in science, technology, engineering, and mathematics (STEM) courses, potentially contributing to gender inequity within these fields.…
The recent surge in valuations among AI related firms has renewed concerns that markets may be entering a new phase of speculative exuberance, especially in the technology and semiconductor sectors at the center of the AI investment wave.…
Investors are interested in predicting future success of startup companies, preferably using publicly available data which can be gathered using free online sources. Using public-only data has been shown to work, but there is still much…
The state of the art on the issue of sex differences in research efficiency agrees in recognizing higher performances for males, however there are divergences in explaining the possible causes. One of the causes advanced is that there are…
Although previous observational studies have shown associations between serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome, this association has not yet been investigated among Aboriginal and Torres Strait Islander…
We derive the effective temperatures and gravities of 461 OB stars in 19 young clusters by fitting the H-gamma profile in their spectra. We use synthetic model profiles for rotating stars to develop a method to estimate the polar gravity…
Nearby associations are excellent objects for the study of the initial spin up phase during the PMS evolution. An empirical approach is adopted here to infer their rotations properties and relations to X-ray emission. Three nearby…
The physical processes driving chemical evolution in the Milky Way can be probed using the distribution of abundances in low-mass FGK type stars in space phase at different times. During their final stages of evolution stars experience…