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A commonly occurring computation idiom in neural networks is to perform some pointwise operations on the result of a matrix multiplication. Such a sequence of operations is typically represented as a computation graph in deep learning…

Programming Languages · Computer Science 2020-08-04 Somashekaracharya G. Bhaskaracharya , Julien Demouth , Vinod Grover

We present SynRXN, a unified benchmarking framework and open-data resource for computer-aided synthesis planning (CASP). SynRXN decomposes end-to-end synthesis planning into five task families, covering reaction rebalancing, atom-to-atom…

Machine Learning · Computer Science 2026-04-21 Tieu-Long Phan , Nhu-Ngoc Nguyen Song , Peter F. Stadler

Developers of Molecular Dynamics (MD) codes face significant challenges when adapting existing simulation packages to new hardware. In a continuously diversifying hardware landscape it becomes increasingly difficult for scientists to be…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-03-14 William R. Saunders , James Grant , Eike H. Müller

We present results from a new Kinetic-Equilibrium Prediction (KEP) workflow and shot preparation for full TCV discharges, by coupling predict-first RAPTOR transport simulations with FBT inverse equilibrium calculations. RAPTOR is a 1.5D…

A finite-difference Micromagnetic simulation code written in MATLAB is presented with Graphics Processing Unit (GPU) acceleration. The high performance of Graphics Processing Unit (GPU) is demonstrated compared to a typical Central…

Computational Engineering, Finance, and Science · Computer Science 2015-01-30 Ru Zhu

The hardware diversity in leadership-class computing facilities, alongside the immense performance boosts from today's GPUs when computing in lower precision, incentivizes scientific HPC workflows to adopt mixed-precision algorithms and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-06 Sreeram Venkat , Kasia Swirydowicz , Noah Wolfe , Omar Ghattas

One of the most promising paths towards large scale fault tolerant quantum computation is the use of quantum error correcting stabilizer codes. Just like every other quantum circuit, these codes must be compiled to hardware in a way to…

Quantum Physics · Physics 2025-08-07 Sahil Khan , Suhas Vittal , Kenneth Brown , Jonathan Baker

The Combustion Toolbox (CT) is a newly developed open-source thermochemical code designed to solve problems involving chemical equilibrium for both gas- and condensed-phase species. The kernel of the code is based on the theoretical…

Chemical Physics · Physics 2026-01-06 Alberto Cuadra , César Huete , Marcos Vera

Software optimization refines programs for resource efficiency while preserving functionality. Traditionally, it is a process done by developers and compilers. This paper introduces a third option, automated optimization at the source code…

Software Engineering · Computer Science 2025-02-04 Zimin Chen , Sen Fang , Martin Monperrus

Applying quantum chemistry algorithms to large-scale systems requires substantial computational resources scaled with the system size and the desired accuracy. To address this, ByteQC, a fully-functional and efficient package for…

Generating high-performance CUDA kernels remains challenging due to the need to navigate a combinatorial space of low-level transformations under noisy and expensive hardware feedback. Although large language models can synthesize…

Machine Learning · Computer Science 2026-02-16 Arijit Bhattacharjee , Heng Ping , Son Vu Le , Paul Bogdan , Nesreen K. Ahmed , Ali Jannesari

Current AI code generation systems suffer from significant latency bottlenecks due to CPU-GPU data transfers during compilation, execution, and testing phases. We establish theoretical foundations for three complementary approaches to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-15 Adilet Metinov , Gulida M. Kudakeeva , Gulnara D. Kabaeva

We show in this work that memory intensive computations can result in severe performance problems due to off-chip memory access and CPU-GPU context switch overheads in a wide range of deep learning models. For this problem, current…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-12-20 Zhen Zheng , Pengzhan Zhao , Guoping Long , Feiwen Zhu , Kai Zhu , Wenyi Zhao , Lansong Diao , Jun Yang , Wei Lin

The field of plasma physics heavily relies on simulations to model various phenomena, such as instabilities, turbulence, and nonlinear behaviors that would otherwise be difficult to study from a purely theoretical approach. Simulations are…

Plasma Physics · Physics 2026-02-05 Giorgio Daneri

Optimizing deep learning models is generally performed in two steps: (i) high-level graph optimizations such as kernel fusion and (ii) low level kernel optimizations such as those found in vendor libraries. This approach often leaves…

Machine Learning · Computer Science 2021-03-08 Pratik Fegade , Tianqi Chen , Phillip B. Gibbons , Todd C. Mowry

Probabilistic reasoning is an essential tool for robust decision-making systems because of its ability to explicitly handle real-world uncertainty, constraints and causal relations. Consequently, researchers are developing hybrid models by…

Hardware Architecture · Computer Science 2021-03-02 Nimish Shah , Laura I. Galindez Olascoaga , Wannes Meert , Marian Verhelst

Quantum computers are becoming practical for computing numerous applications. However, simulating quantum computing on classical computers is still demanding yet useful because current quantum computers are limited because of computer…

Quantum Physics · Physics 2023-08-08 Jun Doi , Hiroshi Horii , Christopher Wood

As computing system become more complex, it is becoming harder for programmers to keep their codes optimized as the hardware gets updated. Autotuners try to alleviate this by hiding as many architecture-based optimization details as…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-17 Jacob O. Tørring , Ben van Werkhoven , Filip Petrovic , Floris-Jan Willemsen , Jirí Filipovic , Anne C. Elster

We present the extension of the Tinker-HP package (Lagard\`ere et al., Chem. Sci., 2018,9, 956-972) to the use of Graphics Processing Unit (GPU) cards to accelerate molecular dynamics simulations using polarizable many-body force fields.…

In this paper we present KiT-RT (Kinetic Transport Solver for Radiation Therapy), an open-source C++ based framework for solving kinetic equations in radiation therapy applications. The aim of this code framework is to provide a collection…

Medical Physics · Physics 2022-05-18 Jonas Kusch , Steffen Schotthöfer , Pia Stammer , Jannick Wolters , Tianbai Xiao