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Precise segmentation of retinal arteries and veins carries the diagnosis of systemic cardiovascular conditions. However, standard convolutional architectures often yield topologically disjointed segmentations, characterized by gaps and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Iftekhar Ahmed , Shakib Absar , Aftar Ahmad Sami , Shadman Sakib , Debojyoti Biswas , Seraj Al Mahmud Mostafa

While message passing graph neural networks result in informative node embeddings, they may suffer from describing the topological properties of graphs. To this end, node filtration has been widely used as an attempt to obtain the…

Machine Learning · Computer Science 2024-12-24 Jaesun Shin , Eunjoo Jeon , Taewon Cho , Namkyeong Cho , Youngjune Gwon

Topological data analysis (TDA) uncovers crucial properties of objects in medical imaging. Methods based on persistent homology have demonstrated their advantages in capturing topological features that traditional deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Yanfan Zhu , Yash Singh , Khaled Younis , Shunxing Bao , Yuankai Huo

Variational models are widely used in image segmentation, with various models designed to address different types of images by optimizing specific objective functionals. However, traditional segmentation models primarily focus on the visual…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Lingyun Deng , Litong Liu , Dong Wang , Xiao-Ping Wang

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

The morphological attributes of retinal vessels, such as length, width, tortuosity and branching pattern and angles, play an important role in diagnosis, screening, treatment, and evaluation of various cardiovascular and ophthalmologic…

Image and Video Processing · Electrical Eng. & Systems 2019-11-25 Zhengyuan Liu

Fundus photography is prone to suffer from image quality degradation that impacts clinical examination performed by ophthalmologists or intelligent systems. Though enhancement algorithms have been developed to promote fundus observation on…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Heng Li , Haofeng Liu , Huazhu Fu , Yanwu Xu , Hui Shu , Ke Niu , Yan Hu , Jiang Liu

Image segmentation is to extract meaningful objects from a given image. For degraded images due to occlusions, obscurities or noises, the accuracy of the segmentation result can be severely affected. To alleviate this problem, prior…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Daoping Zhang , Lok Ming Lui

In ophthalmological imaging, multiple imaging systems, such as color fundus, infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT angiography, are often involved to make a diagnosis of retinal disease. Multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Aline Sindel , Bettina Hohberger , Andreas Maier , Vincent Christlein

Segmentation algorithms are prone to make topological errors on fine-scale structures, e.g., broken connections. We propose a novel method that learns to segment with correct topology. In particular, we design a continuous-valued loss…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Xiaoling Hu , Li Fuxin , Dimitris Samaras , Chao Chen

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

Communication networks form the backbone of our society. Topology control algorithms optimize the topology of such communication networks. Due to the importance of communication networks, a topology control algorithm should guarantee…

Software Engineering · Computer Science 2018-05-10 Roland Kluge , Michael Stein , Gergely Varró , Andy Schürr , Matthias Hollick , Max Mühlhäuser

Modern deep neural networks have achieved great successes in medical image analysis. However, the features captured by convolutional neural networks (CNNs) or Transformers tend to be optimized for pixel intensities and neglect key…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Yaopeng Peng , Hongxiao Wang , Milan Sonka , Danny Z. Chen

Blood vessel segmentation is one of the most studied topics in computer vision, due to its relevance in daily clinical practice. Despite the evolution the field has been facing, especially after the dawn of deep learning, important…

Image and Video Processing · Electrical Eng. & Systems 2021-08-02 R. J. Araújo , J. S. Cardoso , H. P. Oliveira

Optimization, a key tool in machine learning and statistics, relies on regularization to reduce overfitting. Traditional regularization methods control a norm of the solution to ensure its smoothness. Recently, topological methods have…

Machine Learning · Computer Science 2020-11-11 Arnur Nigmetov , Aditi S. Krishnapriyan , Nicole Sanderson , Dmitriy Morozov

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…

Quantitative Methods · Quantitative Biology 2019-07-23 Helen M Byrne , Heather A Harrington , Ruth Muschel , Gesine Reinert , Bernadette J Stolz , Ulrike Tillmann

Learning structural information is critical for producing an ideal result in retinal image segmentation. Recently, convolutional neural networks have shown a powerful ability to extract effective representations. However, convolutional and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-24 Shihao Zhang , Huazhu Fu , Yuguang Yan , Yubing Zhang , Qingyao Wu , Ming Yang , Mingkui Tan , Yanwu Xu

Traditional fundus image analysis models focus on single-modal tasks, ignoring fundus modality complementarity, which limits their versatility. Recently, retinal foundation models have emerged, but most still remain modality-specific.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yuang Yao , Ruiqi Wu , Yi Zhou , Tao Zhou

The caliber and configuration of retinal blood vessels serve as important biomarkers for various diseases and medical conditions. A thorough analysis of the retinal vasculature requires the segmentation of the blood vessels and their…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 José Morano , Guilherme Aresta , Hrvoje Bogunović

Capturing the global topology of an image is essential for proposing an accurate segmentation of its domain. However, most of existing segmentation methods do not preserve the initial topology of the given input, which is detrimental for…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Minh On Vu Ngoc , Yizi Chen , Nicolas Boutry , Jonathan Fabrizio , Clement Mallet