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Representation learning on graphs is a fundamental problem that can be crucial in various tasks. Graph neural networks, the dominant approach for graph representation learning, are limited in their representation power. Therefore, it can be…

Machine Learning · Computer Science 2025-01-17 Zuoyu Yan , Qi Zhao , Ze Ye , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

Non-mydriatic retinal color fundus photography (CFP) is widely available due to the advantage of not requiring pupillary dilation, however, is prone to poor quality due to operators, systemic imperfections, or patient-related causes.…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Wenhui Zhu , Peijie Qiu , Oana M. Dumitrascu , Jacob M. Sobczak , Mohammad Farazi , Zhangsihao Yang , Keshav Nandakumar , Yalin Wang

Topological statistics, in the form of persistence diagrams, are a class of shape descriptors that capture global structural information in data. The mapping from data structures to persistence diagrams is almost everywhere differentiable,…

Machine Learning · Statistics 2021-02-24 Elchanan Solomon , Alexander Wagner , Paul Bendich

Persistent topological properties of an image serve as an additional descriptor providing an insight that might not be discovered by traditional neural networks. The existing research in this area focuses primarily on efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Ekaterina Khramtsova , Guido Zuccon , Xi Wang , Mahsa Baktashmotlagh

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision, including view-point in activity analysis, articulation in shape analysis, and measurement invariance in…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Anirudh Som , Kowshik Thopalli , Karthikeyan Natesan Ramamurthy , Vinay Venkataraman , Ankita Shukla , Pavan Turaga

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Persistence diagrams (PDs) provide a powerful tool for understanding the topology of the underlying shape of a point cloud. However, identifying which points in PDs encode genuine signals remains challenging. This challenge directly hinders…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yu Chen , Hongwei Lin

Topological features play an essential role in ensuring geometric plausibility and structural consistency in image analysis tasks such as segmentation and skeletonization. However, integrating topology-preserving learning based on simple…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Wenxiao Li , Faqiang Wang , Yuping Duan , Li Cui , Liqiang Zhang , Jun Liu

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Aashis Khanal , Saeid Motevali , Rolando Estrada

Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable successes of numerous image processing methods that rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Pengfei Gu , Hongxiao Wang , Yejia Zhang , Huimin Li , Chaoli Wang , Danny Chen

Survival prediction is a complicated ordinal regression task that aims to predict the ranking risk of death, which generally benefits from the integration of histology and genomic data. Despite the progress in joint learning from pathology…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Yingxue Xu , Hao Chen

The morphology and hierarchy of the vascular systems are essential for perfusion in supporting metabolism. In human retina, one of the most energy-demanding organs, retinal circulation nourishes the entire inner retina by an intricate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Siyi Chen , Amir H. Kashani , Ji Yi

Preserving topological structures is important in real-world applications, particularly in sensitive domains such as healthcare and medicine, where the correctness of human anatomy is critical. However, most existing image editing models…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Nivetha Jayakumar , Srivardhan Reddy Gadila , Tonmoy Hossain , Yangfeng Ji , Miaomiao Zhang

In this work we use the persistent homology method, a technique in topological data analysis (TDA), to extract essential topological features from the data space and combine them with deep learning features for classification tasks. In TDA,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Mariana Dória Prata Lima , Gilson Antonio Giraldi , Gastão Florêncio Miranda Junior

Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Ziyi Shen , Huazhu Fu , Jianbing Shen , Ling Shao

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince