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Spleen volumetry is primarily associated with patients suffering from chronic liver disease and portal hypertension, as they often have spleens with abnormal shapes and sizes. However, manually segmenting the spleen to obtain its volume is…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Yuqi Wang , Jacob A. Macdonald , Katelyn R. Morgan , Danielle Hom , Sarah Cubberley , Kassi Sollace , Nicole Casasanto , Islam H. Zaki , Kyle J. Lafata , Mustafa R. Bashir

This study focuses on comparing deep learning methods for the segmentation and quantification of uncertainty in prostate segmentation from MRI images. The aim is to improve the workflow of prostate cancer detection and diagnosis. Seven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Pablo Cesar Quihui-Rubio , Daniel Flores-Araiza , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Christian Mata

Automatic segmentation of vestibular schwannoma (VS) tumors from magnetic resonance imaging (MRI) would facilitate efficient and accurate volume measurement to guide patient management and improve clinical workflow. The accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Guotai Wang , Jonathan Shapey , Wenqi Li , Reuben Dorent , Alex Demitriadis , Sotirios Bisdas , Ian Paddick , Robert Bradford , Sebastien Ourselin , Tom Vercauteren

Prostate cancer (PCa) is one of the most common cancers in men around the world. The most accurate method to evaluate lesion levels of PCa is microscopic inspection of stained biopsy tissue and estimate the Gleason score of tissue…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Yi-hong Zhang , Jing Zhang , Yang Song , Chaomin Shen , Guang Yang

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

Medical image segmentation is an actively studied task in medical imaging, where the precision of the annotations is of utter importance towards accurate diagnosis and treatment. In recent years, the task has been approached with various…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Mariana-Iuliana Georgescu , Radu Tudor Ionescu , Andreea-Iuliana Miron

Image segmentation in the medical domain is a challenging field owing to poor resolution and limited contrast. The predominantly used conventional segmentation techniques and the thresholding methods suffer from limitations because of heavy…

Computer Vision and Pattern Recognition · Computer Science 2016-05-10 Jiyo. S. Athertya , G. Saravana Kumar

High-fidelity semantic segmentation of magnetic resonance volumes is critical for estimating tissue morphometry and relaxation parameters in both clinical and research applications. While manual segmentation is accepted as the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-07 Arjun D. Desai , Garry E. Gold , Brian A. Hargreaves , Akshay S. Chaudhari

Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial…

Machine Learning · Computer Science 2025-02-13 Byron A Jacobs , Ifthakaar Shaik , Frando Lin

Magnetic resonance imaging (MRI) enables non-invasive, high-resolution analysis of muscle structures. However, automated segmentation remains limited by high computational costs, reliance on large training datasets, and reduced accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Mengyuan Liu , Jeongkyu Lee

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

In this paper, we propose a mean score equation-based approach to estimate the the volume under the receiving operating characteristic (ROC) surface (VUS) of a diagnostic test, under nonignorable (NI) verification bias. The proposed…

Methodology · Statistics 2019-06-21 Duc-Khanh To , Gianfranco Adimari , Monica Chiogna

Accurately segmenting different organs from medical images is a critical prerequisite for computer-assisted diagnosis and intervention planning. This study proposes a deep learning-based approach for segmenting various organs from CT and…

Breast MRI provides high-resolution imaging critical for breast cancer screening and preoperative staging. However, existing segmentation methods for breast MRI remain limited in scope, often focusing on only a few anatomical structures,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Qihang Li , Jichen Yang , Yaqian Chen , Yuwen Chen , Hanxue Gu , Lars J. Grimm , Maciej A. Mazurowski

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Automated medical image segmentation is a priority research area for computational methods. In particular, detection of cancerous tumors represents a current challenge in this area with potential for real-world impact. This paper describes…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Jamie A. O'Reilly , Manas Sangworasil , Takenobu Matsuura

We propose BaySize, a sample size calculator for phase I clinical trials using Bayesian models. BaySize applies the concept of effect size in dose finding, assuming the MTD is defined based on an equivalence interval. Leveraging a decision…

Methodology · Statistics 2023-03-29 Xiaolei Lin , Jiaying Lyu , Shijie Yuan , Sue-Jane Wang , Yuan Ji

In this paper we present a new 3D segmentation approach for the vertebrae of the lower thoracic and the lumbar spine in spiral computed tomography datasets. We implemented a multi-step procedure. Its main components are deformable models,…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Andre Mastmeyer , Klaus Engelke , Sebastian Meller , Willi Kalender

The claustrum is a thin gray matter structure in each brain hemisphere, characterized by exceptionally high connectivity with nearly all brain regions. Despite extensive animal studies on its anatomy and function and growing evidence of…

Neurons and Cognition · Quantitative Biology 2025-05-16 Steven Seung-Suk Kang , Joseph Bodenheimer , Kayley Morris , Tracey Butler