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Machine learning driven medical image segmentation has become standard in medical image analysis. However, deep learning models are prone to overconfident predictions. This has led to a renewed focus on calibrated predictions in the medical…

Quantitative computed tomography (QCT) is a standard method to determine bone mineral density (BMD) in the spine. Traditionally single 8 - 10 mm thick slices have been analyzed only. Current spiral CT scanners provide true 3D acquisition…

A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

Is it possible to estimate the dependence of a growing and dividing population on a given trait in the case where this trait is not directly accessible by experimental measurements, but making use of measurements of another variable? This…

Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

The automatic segmentation of kidney, kidney tumor and kidney cyst on Computed Tomography (CT) scans is a challenging task due to the indistinct lesion boundaries and fuzzy texture. Considering the large range and unbalanced distribution of…

Prostate segmentation from Magnetic Resonance (MR) images plays an important role in image guided interven- tion. However, the lack of clear boundary specifically at the apex and base, and huge variation of shape and texture between the…

In the United States, prostate cancer is the second leading cause of deaths in males with a predicted 35,250 deaths in 2024. However, most diagnoses are non-lethal and deemed clinically insignificant which means that the patient will likely…

This research presents an enhanced approach for precise segmentation of brain tumor masses in magnetic resonance imaging (MRI) using an advanced 3D-UNet model combined with a Context Transformer (CoT). By architectural expansion CoT, the…

We introduce Bayesian QuickNAT for the automated quality control of whole-brain segmentation on MRI T1 scans. Next to the Bayesian fully convolutional neural network, we also present inherent measures of segmentation uncertainty that allow…

Promptable segmentation models (e.g., the Segment Anything Models) enable generalizable, zero-shot segmentation across diverse domains. Although predictions are deterministic for a fixed image-prompt pair, the robustness of these models to…

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Biomechanical motion simulation and dynamic analysis of human joint moments will provide insights into Musculoskeletal Disorders. As one of the mainstream simulation tools, OpenSim uses proportional scaling to specify model segment masses…

In this work, we propose a deep U-Net based model to tackle the challenging task of prostate cancer segmentation by aggressiveness in MRI based on weak scribble annotations. This model extends the size constraint loss proposed by Kervadec…

In interactive medical image segmentation, anatomical structures are extracted from reconstructed volumetric images. The first iterations of user interaction traditionally consist of drawing pictorial hints as an initial estimate of the…

Monitoring the progression of lesions is important for clinical response. Summary statistics such as lesion volume are objective and easy to interpret, which can help clinicians assess lesion growth or decay. CNNs are commonly used in…

Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

Uterine fibroids (myomas) are the most common benign tumors of the female reproductive system, particularly among women of childbearing age. With a prevalence exceeding 70%, they pose a significant burden on female reproductive health.…

Deep learning has made significant strides in automated brain tumor segmentation from magnetic resonance imaging (MRI) scans in recent years. However, the reliability of these tools is hampered by the presence of poor-quality segmentation…