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Functional brain networks exhibit topological structures that reflect neural organization; however, statistical comparison of these networks is challenging for several reasons. This paper introduces a topologically invariant permutation…

Neurons and Cognition · Quantitative Biology 2025-12-30 Sixtus Dakurah

This work introduces a novel framework for testing topological variability in weighted networks by combining Hodge decomposition with Wasserstein variance minimization. Traditional approaches that analyze raw edge weights are susceptible to…

Quantitative Methods · Quantitative Biology 2025-11-18 Sixtus Dakurah

Topological data analysis can extract effective information from higher-dimensional data. Its mathematical basis is persistent homology. The persistent homology can calculate topological features at different spatiotemporal scales of the…

Algebraic Topology · Mathematics 2023-09-29 Dinghua Shi , Zhifeng Chen , Chuang Ma , Guanrong Chen

We introduce a new invariant defined on the vertices of a given filtered simplicial complex, called codensity, which controls the impact of removing vertices on persistent homology. We achieve this control through the use of an interleaving…

Algebraic Topology · Mathematics 2018-01-10 Facundo Mémoli , Osman Berat Okutan

Persistent homology, a method from topological data analysis, extracts robust, multi-scale features from data. It produces stable representations of time series by applying varying thresholds to their values (a process known as a…

Computation and Language · Computer Science 2026-04-24 Marius Huber , David R. Reich , Lena A. Jäger

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic

We present a novel method to explicitly incorporate topological prior knowledge into deep learning based segmentation, which is, to our knowledge, the first work to do so. Our method uses the concept of persistent homology, a tool from…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 James R. Clough , Ilkay Oksuz , Nicholas Byrne , Julia A. Schnabel , Andrew P. King

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Topological Data Analysis (TDA) is a rising field of computational topology in which the topological structure of a data set can be observed by persistent homology. By considering a sequence of sublevel sets, one obtains a filtration that…

Methodology · Statistics 2020-03-17 Yu-Min Chung , William Cruse , Austin Lawson

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

Functional magnetic resonance imaging (fMRI) has been commonly used to construct functional connectivity networks (FCNs) of the human brain. TFCNs are primarily limited to quantifying pairwise relationships between ROIs ignoring higher…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Duc Vu , Selin Aviyente

Continuous subgraph matching (CSM) algorithms find the occurrences of a given pattern on a stream of data graphs online. A number of incremental CSM algorithms have been proposed. However, a systematical study on these algorithms is missing…

Databases · Computer Science 2022-03-15 Xibo Sun , Shixuan Sun , Qiong Luo , Bingsheng He

We introduce a method for training neural networks to perform image or volume segmentation in which prior knowledge about the topology of the segmented object can be explicitly provided and then incorporated into the training process. By…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 James R. Clough , Nicholas Byrne , Ilkay Oksuz , Veronika A. Zimmer , Julia A. Schnabel , Andrew P. King

Early detection of cognitive decline is crucial for enabling interventions that can slow neurodegenerative disease progression. Traditional diagnostic approaches rely on labor-intensive clinical assessments, which are impractical for…

Computation and Language · Computer Science 2025-09-04 Kristin Qi , Youxiang Zhu , Caroline Summerour , John A. Batsis , Xiaohui Liang
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