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Mathematical modeling offers a valuable approach to understanding Alzheimers disease (AD) given its complexity, unknown causes, and lack of effective treatments. Models, once validated, offer a powerful tool to test medical hypotheses that…

Analysis of PDEs · Mathematics 2026-03-20 G. Landi , A. Scaravelli , M. C. Tesi , C. Testa

Unlike natural images, medical images often have intrinsic characteristics that can be leveraged for neural network learning. For example, images that belong to different stages of a disease may continuously follow a certain progression…

Computer Vision and Pattern Recognition · Computer Science 2019-05-29 Qicheng Lao , Thomas Fevens , Boyu Wang

Network epidemiology has become a core framework for investigating the role of human contact patterns in the spreading of infectious diseases. In network epidemiology represents the contact structure as a network of nodes (individuals)…

Populations and Evolution · Quantitative Biology 2014-06-10 Petter Holme

We propose a family of statistical models for social network evolution over time, which represents an extension of Exponential Random Graph Models (ERGMs). Many of the methods for ERGMs are readily adapted for these models, including…

Machine Learning · Statistics 2009-08-11 Steve Hanneke , Wenjie Fu , Eric Xing

Spreading models capture key dynamics on networks, such as cascading failures in economic systems, (mis)information diffusion, and pathogen transmission. Here, we focus on design intervention problems -- for example, designing optimal…

Social and Information Networks · Computer Science 2025-09-29 Erik Weis , Laurent Hébert-Dufresne , Jean-Gabriel Young

We analyze a recently proposed temporal centrality measure applied to an empirical network based on person-to-person contacts in an emergency department of a busy urban hospital. We show that temporal centrality identifies a distinct set of…

Physics and Society · Physics 2016-03-15 Isabel Chen , Michele Benzi , Howard H. Chang , Vicki S. Hertzberg

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

The appearance of a new dangerous and contagious disease requires the development of a drug therapy faster than what is foreseen by usual mechanisms. Many drug therapy developments consist in investigating through different clinical trials…

Quantitative Methods · Quantitative Biology 2020-03-31 Ezequiel Alvarez , Federico Lamagna , Manuel Szewc

Emerging infectious diseases and climate change are two of the major challenges in 21st century. Although over the past decades, highly-resolved mathematical models have contributed in understanding dynamics of infectious diseases and are…

Populations and Evolution · Quantitative Biology 2025-10-13 Julia Bicker , René Schmieding , Michael Meyer-Hermann , Martin J. Kühn

This paper proposes a novel approach to predict epidemiological parameters by integrating new real-time signals from various sources of information, such as novel social media-based population density maps and Air Quality data. We implement…

Machine Learning · Computer Science 2023-07-04 Romain Molinas , César Quilodrán Casas , Rossella Arcucci , Ovidiu Şerban

This paper presents a new algorithm, Evolutionary eXploration of Augmenting Memory Models (EXAMM), which is capable of evolving recurrent neural networks (RNNs) using a wide variety of memory structures, such as Delta-RNN, GRU, LSTM, MGU…

Neural and Evolutionary Computing · Computer Science 2019-02-12 Alexander Ororbia , Ahmed Ahmed Elsaid , Travis Desell

This study presents an integrated approach to understanding epidemic dynamics through a stochastic spatio-temporal simulation model on a multiplex network, blending physical and informational layers. The physical layer maps the geographic…

Physics and Society · Physics 2025-09-26 H. M. Shadman Tabib , Jaber Ahmed Deedar , K. M. Ariful Kabir

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. Despite the many advantages of joint modeling, the standard forms suffer from limitations that arise…

Machine Learning · Statistics 2018-07-10 Bryan Lim , Mihaela van der Schaar

The majority of research on epidemics relies on models which are formulated in continuous-time. However, real-world epidemic data is gathered and processed in a digital manner, which is more accurately described by discrete-time epidemic…

Optimization and Control · Mathematics 2021-07-23 Bastian Prasse , Piet Van Mieghem

The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…

Physics and Society · Physics 2019-10-02 Wei Wang , Quan-Hui Liu , Junhao Liang , Yanqing Hu , Tao Zhou

In this brief, we study epidemic spreading dynamics taking place in complex networks. We specifically investigate the effect of synergy, where multiple interactions between nodes result in a combined effect larger than the simple sum of…

Social and Information Networks · Computer Science 2019-04-23 Masaki Ogura , Wenjie Mei , Kenji Sugimoto

This study addresses the challenge of predicting network dynamics, such as forecasting disease spread in social networks or estimating species populations in predator-prey networks. Accurate predictions in large networks are difficult due…

Social and Information Networks · Computer Science 2023-08-23 Rui Luo

The prediction of the behavior of the disease, the level of affectation in a population and the ways to control it are the most important aspects studied by epidemiology using tools such as historical data and mathematical models. So, our…

Dynamical Systems · Mathematics 2022-04-04 Jorge Andrés Ibáñez Huertas , Carlos Isaac Zainea Maya

In this article, we review the literature on statistical theories of neural networks from three perspectives: approximation, training dynamics and generative models. In the first part, results on excess risks for neural networks are…

Machine Learning · Statistics 2024-09-17 Namjoon Suh , Guang Cheng

In real social networks, person-to-person interactions are known to be heterogeneous, which can affect the way a disease spreads through a population, reaches a tipping point in the fraction of infected individuals, and becomes an epidemic.…

Physics and Society · Physics 2020-05-12 Ignacio A. Perez , Paul A. Trunfio , Cristian E. La Rocca , Lidia A. Braunstein