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Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

Cryptography and Security · Computer Science 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

The metaverse promises a host of bright opportunities for business, economics, and society. Though, a number of critical aspects are still to be considered and the analysis of their impact is almost non-existent. In this paper, we provide…

Cryptography and Security · Computer Science 2022-05-17 Roberto Di Pietro , Stefano Cresci

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single- and few-atom thick layers of 2D materials beyond graphene, and also that these materials can exhibit fascinating and…

Mesoscale and Nanoscale Physics · Physics 2022-01-19 Benjamin O. Tayo

Methods for reducing and directly controlling the speed of DNA through a nanopore are needed to enhance sensing performance for direct strand sequencing and detection/mapping of sequence-specific features. We have created a method for…

Biological Physics · Physics 2018-11-28 Xu Liu , Yuning Zhang , Roland Nagel , Walter Reisner , William B. Dunbar

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

Nanotechnology has emerged as a transformative force across multiple industries, enhancing materials, improving instrumentation precision, and developing intelligent systems. This review explores various nanotechnology applications,…

Space Physics · Physics 2025-02-17 Syed Muhammad Muslim Hussain , Batool Zehra Ladha , Muhammad Hasan Khan

Understanding the dissemination of diseases, information, and behavior stands as a paramount research challenge in contemporary network and complex systems science. The COVID-19 pandemic and the proliferation of misinformation are relevant…

Physics and Society · Physics 2024-02-26 Guilherme Ferraz de Arruda , Alberto Aleta , Yamir Moreno

A solid-state nanopore can electrophoretically capture a DNA molecule and pull it through in a folded configuration. The resulting ionic current signal indicates where along its length the DNA was captured. A statistical study using an 8 nm…

Biological Physics · Physics 2015-06-11 Mirna Mihovilovic , Nick Hagerty , Derek Stein

Nanopore sensing is a key technology for single-molecule detection and analysis. Solid-state nanopores have emerged as a versatile platform, since their fabrication allows to engineer their properties by controlling size, shape, and…

Online social media, such as Twitter and Instagram, democratized information broadcast, allowing anyone to share information about themselves and their surroundings at an unprecedented scale. The large volume of information thus posted on…

Social and Information Networks · Computer Science 2019-12-02 Dong Wang , Boleslaw K. Szymanski , Tarek Abdelzaher , Heng Ji , Lance Kaplan

DNA has many valuable characteristics that make it suitable for a long-term storage medium, in particular its durability and high information density. DNA can be stored safely for hundreds of years with virtually no degradation, in contrast…

Quantitative Methods · Quantitative Biology 2022-05-31 Jamie J. Alnasir , Thomas Heinis , Louis Carteron

Portable genome sequencing technology is revolutionizing genomic research by providing a faster, more flexible method of sequencing DNA and RNA [1, 2]. The unprecedented shift from bulky stand-alone benchtop equipment confined in a…

Cryptography and Security · Computer Science 2024-07-18 Carson Stillman , Jonathan E. Bravo , Christina Boucher , Sara Rampazzi

In nanopore sequencing, electrical signal is measured as DNA molecules pass through the sequencing pores. Translating these signals into DNA bases (base calling) is a highly non-trivial task, and its quality has a large impact on the…

Machine Learning · Computer Science 2021-05-18 Vladimír Boža , Peter Perešíni , Broňa Brejová , Tomáš Vinař

In this study, we examine the mechanism of nanopore-based DNA sequencing using a voltage bias across a graphene nanoribbon. Using density functional theory and a non-equilibrium Green's function approach, we determine the transmission…

Mesoscale and Nanoscale Physics · Physics 2018-09-11 Hannah L. McFarland , Towfiq Ahmed , Jian-Xin Zhu , Alexander V. Balatsky , Jason T. Haraldsen

Nanopore protein sequencing produces long, noisy ionic current traces in which key molecular phases, such as protein capture and translocation, are embedded. Capture phases mark the successful entry of a protein into the pore and serve as…

Machine Learning · Computer Science 2025-11-04 Annabelle Martin , Daphne Kontogiorgos-Heintz , Jeff Nivala

Nature (one's genes) and nurture (one's environment) jointly contribute to the formation and evolution of health and human capital over the life cycle. This complex interplay between genes and environment can be estimated and quantified…

Social media platforms continue to struggle with the growing presence of social bots-automated accounts that can influence public opinion and facilitate the spread of disinformation. Over time, these social bots have advanced significantly,…

Social and Information Networks · Computer Science 2025-04-24 Edoardo Allegrini , Edoardo Di Paolo , Marinella Petrocchi , Angelo Spognardi

The epidemiology has recently witnessed great advances based on computational models. Its scope and impact are getting wider thanks to the new data sources feeding analytical frameworks and models. Besides traditional variables considered…

Computers and Society · Computer Science 2023-11-13 David Pastor-Escuredo

Charge transfer can take place along double helical DNA over distances as long as 30 nanometers. However, given the active role of the thermal environment surrounding charge carriers in DNA, physical mechanisms driving the transfer process…

Mesoscale and Nanoscale Physics · Physics 2020-12-04 Roman Korol , Dvira Segal
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