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Social network alignment, aligning different social networks on their common users, is receiving dramatic attention from both academic and industry. All existing studies consider the social network to be static and neglect its inherent…

Social and Information Networks · Computer Science 2019-11-04 Li Sun , Zhongbao Zhang , Pengxin Ji , Jian Wen , Sen Su , Philip S. Yu

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

Genomics · Quantitative Biology 2020-05-01 Khalid Raza , Sabahuddin Ahmad

DNA translocation through nanopores is one of the most promising strategies for the next-generation sequencing technologies. Most part of experimental and numerical works has focused on polymer translocation biased by electrophoresis, where…

Soft Condensed Matter · Physics 2018-02-07 Timothée Menais

In this paper we describe a new technique for the comparison of populations of DNA strands. Comparison is vital to the study of ecological systems, at both the micro and macro scales. Existing methods make use of DNA sequencing and cloning,…

Biomolecules · Quantitative Biology 2008-07-02 Dennis Shasha , Martyn Amos

Fast, reliable and inexpensive DNA sequencing is an important pursuit in healthcare, especially in personalized medicine with possible deep societal impacts. Despite significant progress of various nanopore-based sequencing configurations,…

Proteins are the active working horses in our body. These biomolecules perform all vital cellular functions from DNA replication and general biosynthesis to metabolic signaling and environmental sensing. While static 3D structures are now…

Quantitative Methods · Quantitative Biology 2020-10-16 Sonja Schmid , Cees Dekker

Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Previous theoretical studies have shown that measuring the transverse current across DNA strands while they translocate through a nanopore or channel may provide a statistically distinguishable signature of the DNA bases, and may thus allow…

Soft Condensed Matter · Physics 2009-11-21 Matt Krems , Michael Zwolak , Yuriy V. Pershin , Massimiliano Di Ventra

The development of artificial intelligence (AI) technologies has far exceeded the investigation of their relationship with society. Sociotechnical inquiry is needed to mitigate the harms of new technologies whose potential impacts remain…

Computers and Society · Computer Science 2021-05-18 Sarah Dean , Thomas Krendl Gilbert , Nathan Lambert , Tom Zick

We investigate the dynamics of DNA translocation through a nanopore using 2D Langevin dynamics simulations, focusing on the dependence of the translocation dynamics on the details of DNA sequences. The DNA molecules studied in this work are…

Soft Condensed Matter · Physics 2008-02-05 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

Nanopore sensing is a versatile technique for the analysis of molecules on the single-molecule level. However, extracting information from data with established algorithms usually requires time-consuming checks by an experienced researcher…

Quantitative Methods · Quantitative Biology 2018-06-14 Karolis Misiunas , Niklas Ermann , Ulrich F. Keyser

One of the breakthrough areas of physical science over the past decade has been research in the field of nanostructured materials of various substances, almost all of the properties of which differ sharply from the properties of macroscopic…

Mesoscale and Nanoscale Physics · Physics 2010-08-05 Omar Khazamov , Magomed Ramadanov

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

We propose a DNA sequencing scheme based on silicene nanopores. Using first principles theory, we compute the electrical properties of such pores in the absence and presence of nucleobases. Within a two-terminal geometry, we analyze the…

Quantitative Methods · Quantitative Biology 2014-05-16 Hatef Sadeghi , S. Bailey , Colin J. Lambert

Background: Since the invention of next-generation RNA sequencing (RNA-seq) technologies, they have become a powerful tool to study the presence and quantity of RNA molecules in biological samples and have revolutionized transcriptomic…

Genomics · Quantitative Biology 2021-12-01 Wei Vivian Li , Jingyi Jessica Li

Quantum phenomena are typically observable at length and time scales smaller than those of our everyday experience, often involving individual particles or excitations. The past few decades have seen a revolution in the ability to structure…

The recent progress in DNA sequencing will probably revolutionize the world of electronic. Hence, we went from DNA sequencing that only research centers could realize, to portable, tiny and inexpensive tools. So, it is likely that in a few…

Cryptography and Security · Computer Science 2016-06-22 Amadou Moctar Kane

Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

Hardware Architecture · Computer Science 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

DNA sequencing has faced a huge demand since it was first introduced as a service to the public. This service is often offloaded to the sequencing companies who will have access to full knowledge of individuals' sequences, a major violation…

Information Theory · Computer Science 2019-04-04 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Nanoparticles tethered with DNA strands are promising building blocks for bottom-up nanotechnology, and a theoretical understanding is important for future development. Here we build on approaches developed in polymer physics to provide…

Soft Condensed Matter · Physics 2014-11-03 Chia Wei Hsu , Francesco Sciortino , Francis W. Starr