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This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

In this paper we study the diffusion of an SIS-type epidemics on a network under the presence of a random environment, that enters in the definition of the infection rates of the nodes. Accordingly, we model the infection rates in the form…

Probability · Mathematics 2016-07-25 Stefano Bonaccorsi , Stefania Ottaviano

Adding edges between layers of interconnected networks is an important way to optimize the spreading dynamics. While previous studies mostly focus on the case of adding a single edge, the theoretical optimal strategy for adding multiple…

Physics and Society · Physics 2019-10-09 Liming Pan , Wei Wang , Shimin Cai , Tao Zhou

The conceptual difference between equilibrium and non-equilibrium steady state (NESS) is well established in physics and chemistry. This distinction, however, is not widely appreciated in dynamical descriptions of biological populations in…

Populations and Evolution · Quantitative Biology 2012-02-23 Jia-Zeng Wang , Min Qian , Hong Qian

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

In this study, we address three important challenges related to disease transmissions such as the COVID-19 pandemic, namely, (a) providing an early warning to likely exposed individuals, (b) identifying individuals who are asymptomatic, and…

Populations and Evolution · Quantitative Biology 2021-09-13 Shashanka Ubaru , Lior Horesh , Guy Cohen

This paper considers a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and varying total population. The interaction of the susceptible and infected people is describe by the…

Analysis of PDEs · Mathematics 2024-12-13 Rui Peng , Rachidi B. Salako , Yixiang Wu

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

In this paper we introduce the optimal control of a kinetic model describing agents who migrate on a graph and interact within its nodes exchanging a physical quantity. As a prototype model, we consider the spread of an infectious disease…

Optimization and Control · Mathematics 2026-01-15 Jonathan Franceschi , Nadia Loy

We apply the cavity master equation (CME) approach to epidemics models. We explore mostly the susceptible-infectious-susceptible (SIS) model, which can be readily treated with the CME as a two-state. We show that this approach is more…

Physics and Society · Physics 2021-03-02 Ernesto Ortega , David Machado , Alejandro Lage-Castellanos

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

Populations and Evolution · Quantitative Biology 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

In this paper we investigate a susceptible-infected-susceptible (SIS) epidemic model describing data dissemination in opportunistic networks with heterogeneous setting of transmission parameters. We obtained the estimation of the final…

Social and Information Networks · Computer Science 2014-03-28 Vadim Alexeev , Liudmila Rozanova , Alexander Temerev

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

We consider a class of spreading processes on networks, which generalize commonly used epidemic models such as the SIR model or the SIS model with a bounded number of re-infections. We analyse the related problem of inference of the…

Disordered Systems and Neural Networks · Physics 2024-07-22 D. Ghio , A. L. M. Aragon , I. Biazzo , L. Zdeborova

This paper deals with the spread of diseases over both a population network and an infrastructure network. We develop a layered networked spread model for a susceptible-infected-susceptible (SIS) pathogen-borne disease spreading over a…

Systems and Control · Electrical Eng. & Systems 2021-09-21 Philip E. Pare , Axel Janson , Sebin Gracy , Ji Liu , Henrik Sandberg , Karl H. Johansson

We investigate the sensitivity of epidemic behavior to a bounded susceptibility constraint -- susceptible nodes are infected by their neighbors via the regular SI/SIS dynamics, but subject to a cap on the infection rate. Such a constraint…

Social and Information Networks · Computer Science 2015-02-19 Subhashini Krishnasamy , Siddhartha Banerjee , Sanjay Shakkottai

The SIS (susceptible-infected-susceptible) epidemic model on an arbitrary network, without making approximations, is a $2^n$-state Markov chain with a unique absorbing state (the all-healthy state). This makes analysis of the SIS model and,…

Social and Information Networks · Computer Science 2019-01-21 Navid Azizan Ruhi , Christos Thrampoulidis , Babak Hassibi

Current modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place…

Physics and Society · Physics 2015-04-15 Joaquín Sanz , Cheng-Yi Xia , Sandro Meloni , Yamir Moreno

In this paper we make the first steps to bridge the gap between classic control theory and modern, network-based epidemic models. In particular, we apply nonlinear model predictive control (NMPC) to a pairwise ODE model which we use to…

Classical Analysis and ODEs · Mathematics 2014-02-11 Fanni Sélley , Ádám Besenyei , Istvan Z. Kiss , Péter L. Simon

This research investigates the coupled dynamics of behavior and infectious disease using a mathematical model. We integrate a two-state q-voter opinion process with SIS-type infection dynamics, where transmission rates are influenced by the…

Physics and Society · Physics 2025-12-13 Thomas Goetz , Tyll Krueger , Karol Niedzielewski , Jan Schneider , Barbara Pabjan