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Analogical reasoning, the transfer of relational structures across contexts (e.g., planet is to sun as electron is to nucleus), is fundamental to scientific discovery. Yet human insight is often constrained by domain expertise and…

Machine Learning · Computer Science 2025-10-28 Hongyu Guo

Large Language Models (LLMs) have garnered significant attention due to their remarkable ability to process information across various languages. Despite their capabilities, they exhibit inconsistencies in handling identical queries in…

Computation and Language · Computer Science 2024-06-24 Yue Huang , Chenrui Fan , Yuan Li , Siyuan Wu , Tianyi Zhou , Xiangliang Zhang , Lichao Sun

Large language models (LLMs) have demonstrated their instruction-following capabilities and achieved powerful performance on various tasks. Inspired by their success, recent works in the molecular domain have led to the development of large…

Artificial Intelligence · Computer Science 2026-01-21 Jinyoung Park , Minseong Bae , Jeehye Na , Hyunwoo J. Kim

Code comment generation aims at generating natural language descriptions for a code snippet to facilitate developers' program comprehension activities. Despite being studied for a long time, a bottleneck for existing approaches is that…

Software Engineering · Computer Science 2023-06-16 Mingyang Geng , Shangwen Wang , Dezun Dong , Haotian Wang , Ge Li , Zhi Jin , Xiaoguang Mao , Xiangke Liao

Reinforcement learning (RL) over text representations can be effective for finding high-value policies that can search over graphs. However, RL requires careful structuring of the search space and algorithm design to be effective in this…

Machine Learning · Computer Science 2023-10-05 Raj Ghugare , Santiago Miret , Adriana Hugessen , Mariano Phielipp , Glen Berseth

Background: Over the past few decades, the process and methodology of automated question generation (AQG) have undergone significant transformations. Recent progress in generative natural language models has opened up new potential in the…

Artificial Intelligence · Computer Science 2024-12-06 Dominic Lohr , Marc Berges , Abhishek Chugh , Michael Kohlhase , Dennis Müller

Artificial intelligence (AI) is reshaping computational and network biology by enabling new approaches to decode cellular communication networks. We introduce Hierarchical Molecular Language Models (HMLMs), a novel framework that models…

Molecular Networks · Quantitative Biology 2025-12-16 Hasi Hays , Yue Yu , William J. Richardson

Ensuring that Large Language Models (LLMs) generate text representative of diverse sub-populations is essential, particularly when key concepts related to under-represented groups are scarce in the training data. We address this challenge…

Computation and Language · Computer Science 2024-12-17 Sabit Hassan , Anthony Sicilia , Malihe Alikhani

Recent work on controlled text generation has either required attribute-based fine-tuning of the base language model (LM), or has restricted the parameterization of the attribute discriminator to be compatible with the base autoregressive…

Computation and Language · Computer Science 2022-04-05 Fatemehsadat Mireshghallah , Kartik Goyal , Taylor Berg-Kirkpatrick

This paper presents LightLM, a lightweight Transformer-based language model for generative recommendation. While Transformer-based generative modeling has gained importance in various AI sub-fields such as NLP and vision, generative…

Information Retrieval · Computer Science 2023-10-31 Kai Mei , Yongfeng Zhang

We introduce G2T-LLM, a novel approach for molecule generation that uses graph-to-tree text encoding to transform graph-based molecular structures into a hierarchical text format optimized for large language models (LLMs). This encoding…

Machine Learning · Computer Science 2024-10-04 Zhaoning Yu , Xiangyang Xu , Hongyang Gao

We introduce a new pretraining approach geared for multi-document language modeling, incorporating two key ideas into the masked language modeling self-supervised objective. First, instead of considering documents in isolation, we pretrain…

Computation and Language · Computer Science 2021-09-06 Avi Caciularu , Arman Cohan , Iz Beltagy , Matthew E. Peters , Arie Cattan , Ido Dagan

Chemical reasoning inherently integrates visual, textual, and symbolic modalities, yet existing benchmarks rarely capture this complexity, often relying on simple image-text pairs with limited chemical semantics. As a result, the actual…

Artificial Intelligence · Computer Science 2025-11-25 Zhiyuan Huang , Baichuan Yang , Zikun He , Yanhong Wu , Fang Hongyu , Zhenhe Liu , Lin Dongsheng , Bing Su

This article analyzes the use of Large Language Models (LLMs) as support for the conceptual modeling of relational databases through the automatic generation of Entity-Relationship (ER) diagrams from natural language requirements. The…

Artificial Intelligence · Computer Science 2026-05-13 Arthur F. Siqueira , Carlos D. S. Nogueira , Eduarda Farias , Claudio E. C. Campelo , Júlia Menezes

Recent data-efficient molecular generation approaches exploit graph grammars to introduce interpretability into the generative models. However, grammar learning therein relies on expert annotation or unreliable heuristics for algorithmic…

Artificial Intelligence · Computer Science 2025-05-30 Michael Sun , Weize Yuan , Gang Liu , Wojciech Matusik , Jie Chen

We report a flexible multi-modal mechanics language model, MeLM, applied to solve various nonlinear forward and inverse problems, that can deal with a set of instructions, numbers and microstructure data. The framework is applied to various…

Materials Science · Physics 2023-10-20 Markus J. Buehler

Pre-trained large language models (PLMs) underlie most new developments in natural language processing. They have shifted the field from application-specific model pipelines to a single model that is adapted to a wide range of tasks.…

Computation and Language · Computer Science 2023-06-30 Joshua Maynez , Priyanka Agrawal , Sebastian Gehrmann

Large language models (LLMs) have demonstrated remarkable capabilities across various domains, yet their application to relational deep learning (RDL) remains underexplored. Existing approaches adapt LLMs by traversing relational links…

Computation and Language · Computer Science 2025-06-09 Fang Wu , Vijay Prakash Dwivedi , Jure Leskovec

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

Chemical reaction and retrosynthesis prediction are fundamental tasks in drug discovery. Recently, large language models (LLMs) have shown potential in many domains. However, directly applying LLMs to these tasks faces two major challenges:…

Machine Learning · Computer Science 2025-05-06 Xuan Lin , Qingrui Liu , Hongxin Xiang , Daojian Zeng , Xiangxiang Zeng