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Modern histopathology relies on the microscopic examination of thin tissue sections stained with histochemical techniques, typically using brightfield or fluorescence microscopy. However, the staining of samples can permanently alter their…

Diffusion-based image translation guided by semantic texts or a single target image has enabled flexible style transfer which is not limited to the specific domains. Unfortunately, due to the stochastic nature of diffusion models, it is…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Gihyun Kwon , Jong Chul Ye

Virtual staining leverages computer-aided techniques to transfer the style of histochemically stained tissue samples to other staining types. In virtual staining of pathological images, maintaining strict structural consistency is crucial,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Bing Xiong , Yue Peng , RanRan Zhang , Fuqiang Chen , JiaYe He , Wenjian Qin

We present a rapid, large-field bimodal imaging platform that integrates conventional brightfield microscopy with a lensless IR imaging scanner, enabling whole-slide IR image stack acquisition in minutes. Using a dedicated deep learning…

Diffusion models have demonstrated impressive performance in various image generation, editing, enhancement and translation tasks. In particular, the pre-trained text-to-image stable diffusion models provide a potential solution to the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Tao Yang , Rongyuan Wu , Peiran Ren , Xuansong Xie , Lei Zhang

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation…

Image-to-image translation is an important and challenging problem in computer vision and image processing. Diffusion models (DM) have shown great potentials for high-quality image synthesis, and have gained competitive performance on the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Bo Li , Kaitao Xue , Bin Liu , Yu-Kun Lai

Exemplar-guided image translation, synthesizing photo-realistic images that conform to both structural control and style exemplars, is attracting attention due to its ability to enhance user control over style manipulation. Previous…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Eungbean Lee , Somi Jeong , Kwanghoon Sohn

Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

Histopathological evaluation of tissue samples is a key practice in patient diagnosis and drug development, especially in oncology. Historically, Hematoxylin and Eosin (H&E) has been used by pathologists as a gold standard staining.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amal Lahiani , Jacob Gildenblat , Irina Klaman , Shadi Albarqouni , Nassir Navab , Eldad Klaiman

High-fidelity, high-resolution numerical simulations are crucial for studying complex multiscale phenomena in fluid dynamics, such as turbulent flows and ocean waves. However, direct numerical simulations with high-resolution solvers are…

Numerical Analysis · Mathematics 2025-04-14 Wuzhe Xu , Yulong Lu , Lian Shen , Anqing Xuan , Ali Barzegari

Staining is critical to cell imaging and medical diagnosis, which is expensive, time-consuming, labor-intensive, and causes irreversible changes to cell tissues. Recent advances in deep learning enabled digital staining via supervised model…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Ziwang Xu , Lanqing Guo , Shuyan Zhang , Alex C. Kot , Bihan Wen

In life sciences, fluorescent labeling techniques are used to study molecular structures and interactions of cells. However, this type of cell imaging has its own limitations, one of which is that the process of staining the cells could be…

Image and Video Processing · Electrical Eng. & Systems 2020-05-07 Eunjae Kim

Video Frame Interpolation (VFI) aims to predict the intermediate frame $I_n$ (we use n to denote time in videos to avoid notation overload with the timestep $t$ in diffusion models) based on two consecutive neighboring frames $I_0$ and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Zonglin Lyu , Chen Chen

We introduce DiffusionTrend for virtual fashion try-on, which forgoes the need for retraining diffusion models. Using advanced diffusion models, DiffusionTrend harnesses latent information rich in prior information to capture the nuances of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Wengyi Zhan , Mingbao Lin , Shuicheng Yan , Rongrong Ji

Image deblurring is an ill-posed problem with multiple plausible solutions for a given input image. However, most existing methods produce a deterministic estimate of the clean image and are trained to minimize pixel-level distortion. These…

Computer Vision and Pattern Recognition · Computer Science 2021-12-30 Jay Whang , Mauricio Delbracio , Hossein Talebi , Chitwan Saharia , Alexandros G. Dimakis , Peyman Milanfar

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Adapting pretrained image-based diffusion models to generate temporally consistent videos has become an impactful generative modeling research direction. Training-free noise-space manipulation has proven to be an effective technique, where…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Yitong Deng , Winnie Lin , Lingxiao Li , Dmitriy Smirnov , Ryan Burgert , Ning Yu , Vincent Dedun , Mohammad H. Taghavi

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Hematoxylin and eosin (H&E) staining visualizes histology but lacks specificity for diagnostic markers. Immunohistochemistry (IHC) staining provides protein-targeted staining but is restricted by tissue availability and antibody…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Anran Liu , Xiaofei Wang , Jing Cai , Chao Li