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The molecular simulations solve the equation of motion of molecular systems, making 3D shapes of molecules four-dimensional by adding the time coordinate. These methods have a great potential in drug discovery because they can realistically…

Biomolecules · Quantitative Biology 2023-01-19 Dalibor Trapl , Vojtěch Spiwok

Modeling the dynamic behavior of deformable objects is crucial for creating realistic digital worlds. While conventional simulations produce high-quality motions, their computational costs are often prohibitive. Subspace simulation…

The use of convex regularizers allows for easy optimization, though they often produce biased estimation and inferior prediction performance. Recently, nonconvex regularizers have attracted a lot of attention and outperformed convex ones.…

Optimization and Control · Mathematics 2017-02-14 Quanming Yao , James. T Kwok

Meta-devices have gained significant attention and have been widely utilized in optical systems for focusing and imaging, owing to their lightweight, high-integration, and exceptional-flexibility capabilities. However, based on the…

Simulators based on neural networks offer a path to orders-of-magnitude faster electromagnetic wave simulations. Existing models, however, only address narrowly tailored classes of problems and only scale to systems of a few dozen degrees…

Optics · Physics 2024-04-02 Charles Dove , Jatearoon Boondicharern , Laura Waller

Fast and accurate solutions of time-dependent partial differential equations (PDEs) are of pivotal interest to many research fields, including physics, engineering, and biology. Generally, implicit/semi-implicit schemes are preferred over…

The emergence of deep-learning-based methods to solve image-reconstruction problems has enabled a significant increase in reconstruction quality. Unfortunately, these new methods often lack reliability and explainability, and there is a…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Alexis Goujon , Sebastian Neumayer , Pakshal Bohra , Stanislas Ducotterd , Michael Unser

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Ruiqing Sun , Delong Yang , Shaohui Zhang , Qun Hao

Machine learning assumes a pivotal role in our data-driven world. The increasing scale of models and datasets necessitates quick and reliable algorithms for model training. This dissertation investigates adaptivity in machine learning…

Machine Learning · Computer Science 2023-11-20 Slavomír Hanzely

Enhancing neural networks with knowledge of physical equations has become an efficient way of solving various physics problems, from fluid flow to electromagnetism. Graph neural networks show promise in accurately representing irregularly…

Machine Learning · Computer Science 2022-04-01 Mike Y. Michelis , Robert K. Katzschmann

Solving partial differential equations (PDEs) on shapes underpins many shape analysis and engineering tasks; yet, prevailing PDE solvers operate on polygonal/triangle meshes while modern 3D assets increasingly live as neural…

Machine Learning · Computer Science 2026-05-29 Lilian Welschinger , Yilin Liu , Zican Wang , Niloy Mitra

A growing number of applications in particle physics and beyond use neural networks as unbinned likelihood ratio estimators applied to real or simulated data. Precision requirements on the inference tasks demand a high-level of stability…

High Energy Physics - Phenomenology · Physics 2025-03-04 G. Bruno De Luca , Benjamin Nachman , Eva Silverstein , Henry Zheng

Metasurfaces, typically realized as arrays of nanopillars, transform electromagnetic (EM) fields depending on their geometry and spatial arrangement. For solving the inverse problem of designing new metasurfaces that transform EM fields in…

Training deep neural networks is a highly nontrivial task, involving carefully selecting appropriate training algorithms, scheduling step sizes and tuning other hyperparameters. Trying different combinations can be quite labor-intensive and…

Machine Learning · Computer Science 2017-06-13 Kaifeng Lv , Shunhua Jiang , Jian Li

Machine learning for scientific applications faces the challenge of limited data. We propose a framework that leverages a priori known physics to reduce overfitting when training on relatively small datasets. A deep neural network is…

Machine Learning · Computer Science 2019-11-22 Jonathan B. Freund , Jonathan F. MacArt , Justin Sirignano

Metaoptics are thin, planar surfaces consisting of many subwavelength optical resonators that can be designed to simultaneously control the amplitude, phase, and polarization to arbitrarily shape an optical wavefront much in the same manner…

Computer simulations are invaluable tools for scientific discovery. However, accurate simulations are often slow to execute, which limits their applicability to extensive parameter exploration, large-scale data analysis, and uncertainty…

Machine learning is finding increasingly broad application in the physical sciences. This most often involves building a model relationship between a dependent, measurable output and an associated set of controllable, but complicated,…

Computational Physics · Physics 2018-08-29 Brian K. Spears

Learning-based methods have made significant progress in physics simulation, typically approximating dynamics with a monolithic end-to-end optimized neural network. Although these models offer an effective way to simulation, they may lose…

Machine Learning · Computer Science 2025-12-18 Yifei Li , Haixu Wu , Zeyi Xu , Tuur Stuyck , Wojciech Matusik

The proliferation of complex deep learning (DL) models has revolutionized various applications, including computer vision-based solutions, prompting their integration into real-time systems. However, the resource-intensive nature of these…

Hardware Architecture · Computer Science 2024-06-26 Tushar Prasanna Swaminathan , Christopher Silver , Thangarajah Akilan