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In medical imaging, technical progress or changes in diagnostic procedures lead to a continuous change in image appearance. Scanner manufacturer, reconstruction kernel, dose, other protocol specific settings or administering of contrast…

Machine Learning · Computer Science 2020-07-08 Johannes Hofmanninger , Matthias Perkonigg , James A. Brink , Oleg Pianykh , Christian Herold , Georg Langs

The dynamics of water molecules plays a vital role in understanding water. We combined computer simulation and deep learning to study the dynamics of H-bonds between water molecules. Based on ab initio molecular dynamics simulations and a…

Disordered Systems and Neural Networks · Physics 2021-10-19 Jie Huang , Gang Huang , Shiben Li

Tracking the behaviour of stochastic systems is a crucial task in the statistical sciences. It has recently been shown that quantum models can faithfully simulate such processes whilst retaining less information about the past behaviour of…

Quantum Physics · Physics 2019-01-30 Thomas J. Elliott , Andrew J. P. Garner , Mile Gu

We discuss three different aspects of the quantum dynamics of bio-molecular systems and more generally complex networks in the presence of strongly coupled environments. Firstly, we make a case for the systematic study of fundamental…

Quantum Physics · Physics 2012-02-07 M. B. Plenio , S. F. Huelga

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

This study aims at finding a method for constructing molecular dynamics like models using the formalism of cellular automata for fast simulation of fluid dynamic systems (including compressible phenomena). In as much as the results…

comp-gas · Physics 2009-09-25 Himanshu Agrawal

We view a complex liquid as a network of bonds connecting each particle to its nearest neighbors; the dynamics of this network is a chain of discrete events signaling particles rearrangements. Within this picture, we studied a…

Disordered Systems and Neural Networks · Physics 2012-05-11 Alexander Z. Patashinski , Rafal Orlik , Antoni C. Mitus , Mark A. Ratner , Bartosz A. Grzybowski

We consider the correlations and the hydrodynamic description of random walkers with a general finite memory moving on a $d$ dimensional hypercubic lattice. We derive a drift-diffusion equation and identify a memory-dependent critical…

Statistical Mechanics · Physics 2020-01-29 Eial Teomy , Ralf Metzler

Molecular dynamics (MD) simulations are used in biochemistry, physics, and other fields to study the motions, thermodynamic properties, and the interactions between molecules. Computational limitations and the complexity of these problems,…

Numerical Analysis · Mathematics 2018-01-17 F. Grogan , M. Holst , L. Lindblom , R. Amaro

A new approach to describing correlation properties of complex dynamic systems with long-range memory based on a concept of additive Markov chains (Phys. Rev. E 68, 061107 (2003)) is developed. An equation connecting a memory function of…

Classical Physics · Physics 2007-05-23 S. S. Melnyk , O. V. Usatenko , V. A. Yampol'skii

Mechanical loading generally weakens adhesive structures and eventually leads to their rupture. However, biological systems can adapt to loads by strengthening adhesions, which is essential for maintaining the integrity of tissue and whole…

Biological Physics · Physics 2024-06-03 Andrea Braeutigam , Ahmet Nihat Simsek , Gerhard Gompper , Benedikt Sabass

Adhesion processes of biological membranes that enclose cells and cellular organelles are essential for immune responses, tissue formation, and signaling. These processes depend sensitively on the binding constant K2D of the…

Biomolecules · Quantitative Biology 2015-11-30 Guang-Kui Xu , Jinglei Hu , Reinhard Lipowsky , Thomas R. Weikl

Liquid water is reluctant to lose hydrogen-bond coordination. Here we reveal that it also demands contraction and reorientation of the second molecular shell to compensate for coordination defects. Such molecular principle will be shown to…

Soft Condensed Matter · Physics 2024-08-27 Nicolás A. Loubet , Alejandro R. Verde , Gustavo A. Appignanesi

Thin films, bubbles and membranes are central to numerous natural and engineering processes, i.e., in thin-film solar cells, coatings, biosensors, electrowetting displays, foams, and emulsions. Yet, the characterization and an adequate…

Fluid Dynamics · Physics 2024-07-18 Muhammad Rizwanur Rahman , Li Shen , James P. Ewen , D. M. Heyes , Daniele Dini , E. R. Smith

LLMs are trained once, then deployed into a world that never stops changing. External memory compensates for this, but most systems manage it explicitly rather than letting it adapt on its own. Biological memory works differently: coupled…

Machine Learning · Computer Science 2026-05-08 Andreas Pattichis , Constantine Dovrolis

The dynamics of membrane undulations inside a viscous solvent is governed by distinctive, anomalous, power laws. Inside a viscoelastic continuous medium these universal behaviors are modified by the specific bulk viscoelastic spectrum. Yet,…

Soft Condensed Matter · Physics 2018-02-20 Rony Granek , Haim Diamant

Structure and dynamics of water remain a challenge. Resolving the properties of hydrogen bonding lies at the heart of this puzzle. Here we employ ab initio Molecular Dynamics (AIMD) simulations over a wide temperature range. The total…

Soft Condensed Matter · Physics 2013-04-04 John Tatini Titantah , Mikko Karttunen

Coarse-graining of fully atomistic molecular dynamics simulations is a long-standing goal in order to allow the description of processes occurring on biologically relevant timescales. For example, the prediction of pathways, rates and…

Biological Physics · Physics 2020-06-12 Steffen Wolf , Benjamin Lickert , Simon Bray , Gerhard Stock

The primate heteromodal cortex presents an evident functional modularity at a mesoscopic level, with physiological and anatomical evidence pointing to it as likely substrate of long-term memory. In order to investigate some of its…

Neurons and Cognition · Quantitative Biology 2021-12-09 Carlo Fulvi Mari
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