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Related papers: Longitudinal Causal Image Synthesis

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Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

Computer Vision and Pattern Recognition · Computer Science 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

The Granger framework is useful for discovering causal relations in time-varying signals. However, most Granger causality (GC) methods are developed for densely sampled timeseries data. A substantially different setting, particularly common…

Machine Learning · Computer Science 2024-12-19 Minh Nguyen , Gia H. Ngo , Mert R. Sabuncu

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Computed tomography (CT) is a widely used imaging modality for medical diagnosis and treatment. In electroencephalography (EEG), CT imaging is necessary for co-registering with magnetic resonance imaging (MRI) and for creating more accurate…

Medical Physics · Physics 2019-06-12 Andreas D. Lauritzen , Xenophon Papademetris , Sergei Turovets , John A. Onofrey

Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores…

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tao Tang , Shijie Xu , Jionglong Su , Zhixiang Lu

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Magnetic resonance (MR) and computer tomography (CT) imaging are valuable tools for diagnosing diseases and planning treatment. However, limitations such as radiation exposure and cost can restrict access to certain imaging modalities. To…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Jiayuan Wang , Q. M. Jonathan Wu , Farhad Pourpanah

Corneal diseases are the most common eye disorders. Deep learning techniques are used to per-form automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-30 Samer Kais Jameel , Sezgin Aydin , Nebras H. Ghaeb , Jafar Majidpour , Tarik A. Rashid , Sinan Q. Salih , P. S. JosephNg

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Alzheimer's disease (AD) has become a prevalent neurodegenerative disease worldwide. Traditional diagnosis still relies heavily on medical imaging and clinical assessment by physicians, which is often time-consuming and resource-intensive…

Computation and Language · Computer Science 2026-02-17 Tongze Zhang , Jun-En Ding , Melik Ozolcer , Fang-Ming Hung , Albert Chih-Chieh Yang , Feng Liu , Yi-Rou Ji , Sang Won Bae

Multiple imaging modalities are often used for disease diagnosis, prediction, or population-based analyses. However, not all modalities might be available due to cost, different study designs, or changes in imaging technology. If the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Boqi Chen , Marc Niethammer

Training data for class-conditional image synthesis often exhibit a long-tailed distribution with limited images for tail classes. Such an imbalance causes mode collapse and reduces the diversity of synthesized images for tail classes. For…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Fang Chen , Alex Villa , Gongbo Liang , Xiaoyi Lu , Meng Tang

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal…

Methodology · Statistics 2024-08-14 Carlo Berzuini , Davide Luciani , Hiren C. Patel

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

The application of causal discovery to diseases like Alzheimer's (AD) is limited by the static graph assumptions of most methods; such models cannot account for an evolving pathophysiology, modulated by a latent disease pseudotime. We…

Applications · Statistics 2025-11-07 Natalia Glazman , Jyoti Mangal , Pedro Borges , Sebastien Ourselin , M. Jorge Cardoso
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