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Pre-trained large language models (PLMs) underlie most new developments in natural language processing. They have shifted the field from application-specific model pipelines to a single model that is adapted to a wide range of tasks.…

Computation and Language · Computer Science 2023-06-30 Joshua Maynez , Priyanka Agrawal , Sebastian Gehrmann

Although pretrained language models (PLMs) can be prompted to perform a wide range of language tasks, it remains an open question how much this ability comes from generalizable linguistic understanding versus surface-level lexical patterns.…

Computation and Language · Computer Science 2023-05-23 Terra Blevins , Hila Gonen , Luke Zettlemoyer

By conditioning on natural language instructions, large language models (LLMs) have displayed impressive capabilities as general-purpose computers. However, task performance depends significantly on the quality of the prompt used to steer…

Machine Learning · Computer Science 2023-03-13 Yongchao Zhou , Andrei Ioan Muresanu , Ziwen Han , Keiran Paster , Silviu Pitis , Harris Chan , Jimmy Ba

Natural Language Processing (NLP) has transformed various fields beyond linguistics by applying techniques originally developed for human language to the analysis of biological sequences. This review explores the application of NLP methods…

Computation and Language · Computer Science 2025-06-04 Ella Rannon , David Burstein

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

Computation and Language · Computer Science 2023-12-12 Cheng Peng , Xi Yang , Aokun Chen , Zehao Yu , Kaleb E Smith , Anthony B Costa , Mona G Flores , Jiang Bian , Yonghui Wu

Inspired by the success of large language models (LLM) for DNA and proteins, several LLM for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to learn, in a self-supervised way, how to represent each RNA base…

Artificial Intelligence · Computer Science 2025-02-04 L. I. Zablocki , L. A. Bugnon , M. Gerard , L. Di Persia , G. Stegmayer , D. H. Milone

Recent advances in large language models (LLMs) have stepped forward the development of multilingual speech and machine translation by its reduced representation errors and incorporated external knowledge. However, both translation tasks…

Computation and Language · Computer Science 2024-05-17 Yuchen Hu , Chen Chen , Chao-Han Huck Yang , Ruizhe Li , Dong Zhang , Zhehuai Chen , Eng Siong Chng

Large Language Models (LLMs) have been increasingly used to optimize the analysis and synthesis of legal documents, enabling the automation of tasks such as summarization, classification, and retrieval of legal information. This study aims…

Computation and Language · Computer Science 2025-04-02 Matheus Belarmino , Rackel Coelho , Roberto Lotudo , Jayr Pereira

The increasing penetration of distributed energy resources into active distribution networks (ADNs) has made effective ADN dispatch imperative. However, the numerous newly-integrated ADN operators, such as distribution system aggregators,…

Artificial Intelligence · Computer Science 2025-07-30 Xu Yang , Chenhui Lin , Yue Yang , Qi Wang , Haotian Liu , Haizhou Hua , Wenchuan Wu

Generative large language models (LLMs) have demonstrated exceptional proficiency in various natural language processing (NLP) tasks, including machine translation, question answering, text summarization, and natural language understanding.…

Computation and Language · Computer Science 2024-01-17 Nooshin Pourkamali , Shler Ebrahim Sharifi

Large Language Models (LLMs) have revolutionized the field of Natural Language Processing (NLP) by automating traditional labor-intensive tasks and consequently accelerated the development of computer-aided applications. As researchers…

Computation and Language · Computer Science 2025-06-24 Summra Saleem , Muhammad Nabeel Asim , Shaista Zulfiqar , Andreas Dengel

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

The remarkable performance of large language models (LLMs) in zero-shot language understanding has garnered significant attention. However, employing LLMs for large-scale inference or domain-specific fine-tuning requires immense…

Computation and Language · Computer Science 2024-04-16 Ruohong Zhang , Yau-Shian Wang , Yiming Yang

Large language models (LLMs) have demonstrated impressive performance across a wide range of Natural Language Processing (NLP) tasks. However, ensuring their effectiveness across multiple languages presents unique challenges. Multilingual…

Computation and Language · Computer Science 2025-05-20 Shubham Vatsal , Harsh Dubey , Aditi Singh

Advances in large language models (LLMs) have empowered a variety of applications. However, there is still a significant gap in research when it comes to understanding and enhancing the capabilities of LLMs in the field of mental health. In…

Computation and Language · Computer Science 2024-01-30 Xuhai Xu , Bingsheng Yao , Yuanzhe Dong , Saadia Gabriel , Hong Yu , James Hendler , Marzyeh Ghassemi , Anind K. Dey , Dakuo Wang

Large language models (LLMs) have revolutionized natural language processing and are increasingly applied to other sequential data types, including genetic sequences. However, adapting LLMs to genomics presents significant challenges.…

Machine Learning · Computer Science 2025-10-29 Qihao Duan , Bingding Huang , Zhenqiao Song , Irina Lehmann , Lei Gu , Roland Eils , Benjamin Wild

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Prompt engineering has emerged as an indispensable technique for extending the capabilities of large language models (LLMs) and vision-language models (VLMs). This approach leverages task-specific instructions, known as prompts, to enhance…

Artificial Intelligence · Computer Science 2025-03-18 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Vinija Jain , Samrat Mondal , Aman Chadha

Recently, the Large Language Model-based Phoneme-to-Grapheme (LLM-P2G) method has shown excellent performance in speech recognition tasks and has become a feasible direction to replace the traditional WFST decoding method. This framework…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-23 Te Ma , Nanjie Li , Hao Huang , Zhijian Ou

With the success of large-scale pre-training in language tasks, there is an increasing trend of applying it to the domain of life sciences. In particular, pre-training methods based on DNA sequences have received increasing attention…

Artificial Intelligence · Computer Science 2024-09-10 Chaoqi Liang , Lifeng Qiao , Peng Ye , Nanqing Dong , Jianle Sun , Weiqiang Bai , Yuchen Ren , Xinzhu Ma , Hongliang Yan , Chunfeng Song , Wanli Ouyang , Wangmeng Zuo