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Ordinary differential equation models facilitate the understanding of cellular signal transduction and other biological processes. However, for large and comprehensive models, the computational cost of simulating or calibrating can be…

Quantitative Methods · Quantitative Biology 2023-11-29 Fabian Fröhlich , Daniel Weindl , Yannik Schälte , Dilan Pathirana , Łukasz Paszkowski , Glenn Terje Lines , Paul Stapor , Jan Hasenauer

Processing-In-Memory (PIM) is a novel approach that augments existing DRAM memory chips with lightweight logic. By allowing to offload computations to the PIM system, this architecture allows for circumventing the data-bottleneck problem…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-18 André Lopes , Daniel Castro , Paolo Romano

Memristors are promising next-generation memory candidates that are nonvolatile, possess low power requirements and are capable of nanoscale fabrication. In this article we physically realise and describe the use of organic memristors in…

Emerging Technologies · Computer Science 2012-12-17 Victor Erokhin , Gerard David Howard , Andrew Adamatzky

We suggest an approach to use memristors (resistors with memory) in programmable analog circuits. Our idea consists in a circuit design in which low voltages are applied to memristors during their operation as analog circuit elements and…

Instrumentation and Detectors · Physics 2014-11-20 Yuriy V. Pershin , Massimiliano Di Ventra

The statelessness of foundation models bottlenecks agentic systems' ability to continually learn, a core capability for long-horizon reasoning and adaptation. To address this limitation, agentic systems commonly incorporate memory modules…

Artificial Intelligence · Computer Science 2026-02-10 Yiming Xiong , Shengran Hu , Jeff Clune

Memristor has great application prospects in various high-performance electronic systems, such as memory, artificial intelligence, and neural networks, due to its fast speed, nano-scale dimensions, and low-power consumption. However,…

Applied Physics · Physics 2018-12-04 Wei Hu , Du Yongqian , Haibo Luo , Chuandong Chen , Rongshan Wei

Recent advances in silicon photonics promise to revolutionize modern technology by improving performance of everyday devices in multiple fields. However, as the industry moves into a mass fabrication phase, the problem of effective testing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Jaime Gonzalo Flor Flores , Connor Nasseraddin , Jim Solomon , Talha Yerebakan , Andrey B. Matsko , Chee Wei Wong

This paper introduces a novel simulation tool for analyzing and training neural network models tailored for compute-in-memory hardware. The tool leverages physics-based device models to enable the design of neural network models and their…

Hardware Architecture · Computer Science 2023-05-02 Carl Brando , Minseong Park , Sayma Nowshin Chowdhury , Matthew Chen , Kyusang Lee , Sahil Shah

In this paper is proposed a technique to integrate and simulate a dynamic memory in a multiprocessor framework based on C/C++/SystemC. Using host machine's memory management capabilities, dynamic data processing is supported without…

Hardware Architecture · Computer Science 2011-11-09 O. Villa , P. Schaumont , I. Verbauwhede , M. Monchiero , G. Palermo

Flexibility at hardware level is the main driving force behind adaptive systems whose aim is to realise microarhitecture deconfiguration 'online'. This feature allows the software/hardware stack to tolerate drastic changes of the workload…

Hardware Architecture · Computer Science 2016-12-28 Ana Lava , Mahdi Jelodari Mamaghani , Siamak Mohammadi , Steve Furber

Data-intensive computing tasks, such as training neural networks, are crucial for artificial intelligence applications but often come with high energy demands. One promising solution is to develop specialized hardware that directly maps…

Hardware Architecture · Computer Science 2025-02-04 Ankur Singh , Dowon Kim , Byung-Geun Lee

For the self-consistent description of various plasma sources operated in the low-pressure (nonlocal, kinetic) regime, the Particle-In-Cell simulation approach, combined with the Monte Carlo treatment of collision processes (PIC/MCC), has…

Due to the very rapidly growing use of Artificial Neural Networks (ANNs) in real-world applications related to machine learning and Artificial Intelligence (AI), several hardware accelerator de-signs for ANNs have been proposed recently. In…

Hardware Architecture · Computer Science 2021-03-09 Supreeth Mysore Shivanandamurthy , Ishan. G. Thakkar , Sayed Ahmad Salehi

Sequence alignment is a memory bound computation whose performance in modern systems is limited by the memory bandwidth bottleneck. Processing-in-memory architectures alleviate this bottleneck by providing the memory with computing…

Hardware Architecture · Computer Science 2023-03-28 Safaa Diab , Amir Nassereldine , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu , Izzat El Hajj

We introduce MOSAIC, a Python program for machine learning models. Our framework is developed with in mind accelerating machine learning studies through making implementing and testing arbitrary network architectures and data sets simpler,…

Machine Learning · Computer Science 2023-01-31 Mattéo Papin , Yann Beaujeault-Taudière , Frédéric Magniette

An instrumentation amplifier (InAmp) is an electronic device used in many applications, where test and measuring accuracy is required. However, one of the drawbacks of an InAmp is limited operation gain range. In this paper, we investigate…

Emerging Technologies · Computer Science 2019-08-28 Ulzhan Bassembek , Olga Krestinskaya

Computing-in-Memory (CIM) macros have gained popularity for deep learning acceleration due to their highly parallel computation and low power consumption. However, limited macro size and ADC precision introduce throughput and accuracy…

Hardware Architecture · Computer Science 2026-05-01 Ming-Han Lin , Tian-Sheuan Chang

Aside from recent advances in artificial intelligence (AI) models, specialized AI hardware is crucial to address large volumes of unstructured and dynamic data. Hardware-based AI, built on conventional complementary metal-oxidesemiconductor…

Hyperdimensional computing (HDC), utilizing a parallel computing paradigm and efficient learning algorithm, is well-suited for resource-constrained artificial intelligence (AI) applications, such as in edge devices. In-memory computing…

Emerging Technologies · Computer Science 2025-12-25 Yi Huang , Alireza Jaberi Rad , Qiangfei Xia

Simulators for the RISC-V instruction set architecture (ISA) are useful for teaching assembly language and modern CPU architecture concepts. The Assembly/Simulation Platform for Illustration of RISC-V in Education (ASPIRE) is an integrated…

Hardware Architecture · Computer Science 2023-04-25 Marwan Shaban , Adam J. Rocke
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