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Vision-language foundation models (VLMs) show promise for diverse imaging tasks but often underperform on medical benchmarks. Prior efforts to improve performance include model finetuning, which requires large domain-specific datasets and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Arnav Singhvi , Vasiliki Bikia , Asad Aali , Akshay Chaudhari , Roxana Daneshjou

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

The linking of clinical entities is a crucial part of extracting structured information from clinical texts. It is the process of assigning a code from a medical ontology or classification to a phrase in the text. The International…

Computation and Language · Computer Science 2025-09-08 Sylvia Vassileva , Ivan Koychev , Svetla Boytcheva

Automatic ICD coding from clinical text is a critical task in medical NLP but remains hindered by the extreme long-tail distribution of diagnostic codes. Thousands of rare and zero-shot ICD codes are severely underrepresented in datasets…

Computation and Language · Computer Science 2025-11-19 Truong Vo , Weiyi Wu , Kaize Ding

By processing electronic health records (EHRs) as natural language sequences, large language models (LLMs) have shown potential in clinical prediction tasks such as mortality prediction and phenotyping. However, longitudinal or highly…

Computation and Language · Computer Science 2026-05-13 Mingcheng Zhu , Zhiyao Luo , Yu Liu , Tingting Zhu

Background: Medical coding structures healthcare data for research, quality monitoring, and policy. This study assesses the potential of large language models (LLMs) to assign ICPC-2 codes using the output of a domain-specific search…

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and…

Machine Learning · Computer Science 2025-07-18 Weijieying Ren , Jingxi Zhu , Zehao Liu , Tianxiang Zhao , Vasant Honavar

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

A ubiquitous task in processing electronic medical data is the assignment of standardized codes representing diagnoses and/or procedures to free-text documents such as medical reports. This is a difficult natural language processing task…

Misdiagnosis rates are one of the leading causes of medical errors in hospitals, affecting over 12 million adults across the US. To address the high rate of misdiagnosis, this study utilizes 4 NLP-based algorithms to determine the…

Machine Learning · Computer Science 2022-06-29 Krish Maniar , Shafin Haque , Kabir Ramzan

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Large language models (LLMs) have shown exceptional performance on a variety of natural language tasks. Yet, their capabilities for HTML understanding -- i.e., parsing the raw HTML of a webpage, with applications to automation of web-based…

Electronic health records (EHRs), digital collections of patient healthcare events and observations, are ubiquitous in medicine and critical to healthcare delivery, operations, and research. Despite this central role, EHRs are notoriously…

Large language models (LLMs) have shown promising results for software engineering applications, but still struggle with code reasoning tasks such as vulnerability detection (VD). We introduce ConceptCoder, a fine-tuning method that…

Software Engineering · Computer Science 2026-03-25 Md Mahbubur Rahman , Hengbo Tong , Wei Le

We introduce SoftTiger, a clinical large language model (CLaM) designed as a foundation model for healthcare workflows. The narrative and unstructured nature of clinical notes is a major obstacle for healthcare intelligentization. We…

Computation and Language · Computer Science 2024-08-21 Ye Chen , Igor Couto , Wei Cai , Cong Fu , Bruno Dorneles

Clinical texts, represented in electronic medical records (EMRs), contain rich medical information and are essential for disease prediction, personalised information recommendation, clinical decision support, and medication pattern mining…

Computation and Language · Computer Science 2023-10-10 Hangyu Tu , Lifeng Han , Goran Nenadic

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

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