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Artificial intelligence systems show promise to aid in the di- agnostic pathway of prostate cancer (PC), by supporting radiologists in interpreting magnetic resonance images (MRI) of the prostate. Most MRI-based systems are designed to…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Erlend Sortland Rolfsnes , Philip Thangngat , Trygve Eftestøl , Tobias Nordström , Fredrik Jäderling , Martin Eklund , Alvaro Fernandez-Quilez

With the advances in artificial intelligence (AI), data-driven algorithms are becoming increasingly popular in the medical domain. However, due to the nonlinear and complex behavior of many of these algorithms, decision-making by such…

Quantitative Methods · Quantitative Biology 2024-07-18 Amirehsan Ghasemi , Soheil Hashtarkhani , David L Schwartz , Arash Shaban-Nejad

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

The discovery of important biomarkers is a significant step towards understanding the molecular mechanisms of carcinogenesis; enabling accurate diagnosis for, and prognosis of, a certain cancer type. Before recommending any diagnosis,…

Quantitative Methods · Quantitative Biology 2019-09-11 Md. Rezaul Karim , Michael Cochez , Oya Beyan , Stefan Decker , Christoph Lange

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Remy Peyret , Duaa alSaeed , Fouad Khelifi , Nadia Al-Ghreimil , Heyam Al-Baity , Ahmed Bouridane

The overexpression of human epidermal growth factor receptor 2 (HER2) has been established as a therapeutic target in multiple types of cancers, such as breast and gastric cancers. Immunohistochemistry (IHC) is employed as a basic HER2 test…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Jun Zhang , Kuan Tian , Pei Dong , Haocheng Shen , Kezhou Yan , Jianhua Yao , Junzhou Huang , Xiao Han

The use of machine learning and AI on electronic health records (EHRs) holds substantial potential for clinical insight. However, this approach faces challenges due to data heterogeneity, sparsity, temporal misalignment, and limited labeled…

The deployment of Machine Learning models intraoperatively for tissue characterisation can assist decision making and guide safe tumour resections. For image classification models, pixel attribution methods are popular to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Alfie Roddan , Chi Xu , Serine Ajlouni , Irini Kakaletri , Patra Charalampaki , Stamatia Giannarou

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI) applications improving MRI-based detection of clinically significant prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Hassan Jahanandish , Shengtian Sang , Cynthia Xinran Li , Sulaiman Vesal , Indrani Bhattacharya , Jeong Hoon Lee , Richard Fan , Geoffrey A. Sonna , Mirabela Rusu

In recent years, the field of medicine has been increasingly adopting artificial intelligence (AI) technologies to provide faster and more accurate disease detection, prediction, and assessment. In this study, we propose an interpretable AI…

Recent brain tumor classification methods often report high accuracy but rely on deep, over-parameterized architectures with limited interpretability, making it difficult to determine whether predictions are driven by tumor-relevant…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rajan Das Gupta , Md Imrul Hasan Showmick , Lei Wei , Mushfiqur Rahman Abir , Shanjida Akter , Md. Yeasin Rahat , Md. Jakir Hossen

Breast cancer is considered the most critical and frequently diagnosed cancer in women worldwide, leading to an increase in cancer-related mortality. Early and accurate detection is crucial as it can help mitigate possible threats while…

Tree-based machine learning models such as random forests, decision trees, and gradient boosted trees are the most popular non-linear predictive models used in practice today, yet comparatively little attention has been paid to explaining…

We propose an automated method for detecting aggressive prostate cancer(CaP) (Gleason score >=7) based on a comprehensive analysis of the lesion and the surrounding normal prostate tissue which has been simultaneously captured in…

Computer Vision and Pattern Recognition · Computer Science 2016-12-02 Imon Banerjee , Lewis Hahn , Geoffrey Sonn , Richard Fan , Daniel L. Rubin

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

Machine Learning · Computer Science 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li