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The evaluation of the Human Epidermal growth factor Receptor-2 (HER2) expression is an important prognostic biomarker for breast cancer treatment selection. However, HER2 scoring has notoriously high interobserver variability due to stain…

Image and Video Processing · Electrical Eng. & Systems 2022-11-18 Manh Dan Pham , Cyprien Tilmant , Stéphanie Petit , Isabelle Salmon , Saima Ben Hadj , Rutger H. J. Fick

Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide…

Machine Learning · Computer Science 2022-02-07 Panagiota Karatza , Kalliopi V. Dalakleidi , Maria Athanasiou , Konstantina S. Nikita

Gastric endoscopic screening is an effective way to decide appropriate gastric cancer (GC) treatment at an early stage, reducing GC-associated mortality rate. Although artificial intelligence (AI) has brought a great promise to assist…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Yujin Oh , Go Eun Bae , Kyung-Hee Kim , Min-Kyung Yeo , Jong Chul Ye

Prostate cancer is the most abundant cancer in men, with over 200,000 expected new cases and around 28,000 deaths in 2012 in the US alone. In this study, the segmentation results for the prostate central gland (PCG) in MR scans are…

Computer Vision and Pattern Recognition · Computer Science 2013-10-15 Jan Egger

Artificial Intelligence (AI), and in particular, the explainability thereof, has gained phenomenal attention over the last few years. Whilst we usually do not question the decision-making process of these systems in situations where only…

Artificial Intelligence · Computer Science 2021-01-29 Iena Petronella Derks , Alta de Waal

Understanding the molecular processes that drive cellular life is a fundamental question in biological research. Ambitious programs have gathered a number of molecular datasets on large populations. To decipher the complex cellular…

Genomics · Quantitative Biology 2023-03-22 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Jean-Michel Arbona , Benjamin Audit , Pierre Borgnat

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Skin cancer is one of the most common cancers worldwide and early detection is critical for effective treatment. However, current AI diagnostic tools are often trained on datasets dominated by lighter skin tones, leading to reduced accuracy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Areez Muhammed Shabu , Mohammad Samar Ansari , Asra Aslam

Clinical decision support for histopathology image data mainly focuses on strongly supervised annotations, which offers intuitive interpretability, but is bound by expert performance. Here, we propose an explainable cancer relapse…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Esther Dietrich , Patrick Fuhlert , Anne Ernst , Guido Sauter , Maximilian Lennartz , H. Siegfried Stiehl , Marina Zimmermann , Stefan Bonn

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Basal cell carcinoma (BCC) accounts for about 75% of skin cancers. The adoption of teledermatology protocols in Spanish public hospitals has increased dermatologists' workload, motivating the development of AI tools for lesion…

Machine Learning · Computer Science 2026-03-17 Iván Matas , Carmen Serrano , Francisca Silva , Amalia Serrano , Tomás Toledo-Pastrana , Begoña Acha

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the limitations in precision of traditional diagnostic methods such as the Digital Rectal Exam (DRE), Prostate-Specific Antigen (PSA) testing, and…

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Dermatological conditions affect 1.9 billion people globally, yet accurate diagnosis remains challenging due to limited specialist availability and complex clinical presentations. Family history significantly influences skin disease…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Satya Narayana Panda , Vaishnavi Kukkala , Spandana Iyer

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Brain cancer represents a major challenge in medical diagnostics, requisite precise and timely detection for effective treatment. Diagnosis initially relies on the proficiency of radiologists, which can cause difficulties and threats when…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Md. Arafat Alam Khandaker , Ziyan Shirin Raha , Salehin Bin Iqbal , M. F. Mridha , Jungpil Shin

Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Carlos Nácher Collado

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

MOTIVATION: Detection of prostate cancer during transrectal ultrasound-guided biopsy is challenging. The highly heterogeneous appearance of cancer, presence of ultrasound artefacts, and noise all contribute to these difficulties. Recent…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Mahdi Gilany , Paul Wilson , Amoon Jamzad , Fahimeh Fooladgar , Minh Nguyen Nhat To , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj
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