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Related papers: Mathematical modelling to inform outbreak response…

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Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

Epidemiological models increasingly rely on self-reported behavioral data such as vaccination status, mask usage, and social distancing adherence to forecast disease transmission and assess the impact of non-pharmaceutical interventions…

Computer Science and Game Theory · Computer Science 2026-02-24 Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Bud Mishra , Naren Ramakrishnan

Spreading models capture key dynamics on networks, such as cascading failures in economic systems, (mis)information diffusion, and pathogen transmission. Here, we focus on design intervention problems -- for example, designing optimal…

Social and Information Networks · Computer Science 2025-09-29 Erik Weis , Laurent Hébert-Dufresne , Jean-Gabriel Young

Advances in machine learning have enabled the prediction of immune system responses to prophylactic and therapeutic vaccines. However, the engineering task of designing vaccines remains a challenge. In particular, the genetic variability of…

Quantitative Methods · Quantitative Biology 2023-01-30 Zheng Dai , David Gifford

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

In this work we applied several concepts on the modeling of complex systems in an attempt to save mankind in the case of a zombie apocalypse. We developed a dynamical system in order to model a zombie outbreak in which we, regular humans,…

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

Infectious diseases continue to pose significant public health challenges worldwide, requiring effective prevention and control strategies to mitigate their negative impact. Infectious diseases can be broadly classified into two groups:…

Populations and Evolution · Quantitative Biology 2026-04-23 Rupchand Sutradhar , Anuj Mishra , Malay Banerjee , Subhra Sankar Dhar

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Epidemic outbreaks pose significant challenges to public health and socio-economic stability, necessitating a comprehensive understanding of disease transmission dynamics and effective control strategies. This article discusses the…

Physics and Society · Physics 2023-10-20 Sourin Chatterjee , Ahad N. Zehmakan , Sujay Rastogi

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

Physics and Society · Physics 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Finding optimal policies to reduce the morbidity and mortality of the ongoing pandemic is a top public health priority. Using a compartmental model with age structure and vaccination status, we examined the effect of age specific scheduling…

Populations and Evolution · Quantitative Biology 2012-02-29 Diána Knipl , Gergely Röst

Mathematical modelling has a long history in the context of collective cell migration, with applications throughout development, disease and regenerative medicine. The aim of modelling in this context is to provide a framework in which to…

Quantitative Methods · Quantitative Biology 2025-06-24 Ruth E. Baker , Rebecca M. Crossley , Carles Falco , Simon F. Martina-Perez

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

Decisions on public health interventions to control infectious disease are often informed by computational models. Interpreting the predicted outcomes of a public health decision requires not only high-quality modelling, but also an ethical…

Social network analysis is now widely used to investigate the dynamics of infectious disease spread from person to person. Vaccination dramatically disrupts the disease transmission process on a contact network, and indeed, sufficiently…

Physics and Society · Physics 2012-11-05 Ellsworth Campbell , Marcel Salathé

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu