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3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Generative models using neural network have opened a door to large-scale studies for various application domains, especially for studies that suffer from lack of real samples to obtain statistically robust inference. Typically, these…

Computer Vision and Pattern Recognition · Computer Science 2018-12-12 Seong Jae Hwang , Zirui Tao , Won Hwa Kim , Vikas Singh

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Generative models have made significant progress in the tasks of modeling complex data distributions such as natural images. The introduction of Generative Adversarial Networks (GANs) and auto-encoders lead to the possibility of training on…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Tobias Hinz , Stefan Wermter

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Jee Seok Yoon , Chenghao Zhang , Heung-Il Suk , Jia Guo , Xiaoxiao Li

Deep generative models are proficient in generating realistic data but struggle with producing rare samples in low density regions due to their scarcity of training datasets and the mode collapse problem. While recent methods aim to improve…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Subeen Lee , Jiyeon Han , Soyeon Kim , Jaesik Choi

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

Generative models are used as an alternative data augmentation technique to alleviate the data scarcity problem faced in the medical imaging field. Diffusion models have gathered special attention due to their innovative generation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Ricardo Montoya-del-Angel , Karla Sam-Millan , Joan C Vilanova , Robert Martí

Augmentation by generative modelling yields a promising alternative to the accumulation of surgical data, where ethical, organisational and regulatory aspects must be considered. Yet, the joint synthesis of (image, mask) pairs for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yannik Frisch , Christina Bornberg , Moritz Fuchs , Anirban Mukhopadhyay

A ubiquitous challenge in machine learning is the problem of domain generalisation. This can exacerbate bias against groups or labels that are underrepresented in the datasets used for model development. Model bias can lead to unintended…

Generative AI models have revolutionized various fields by enabling the creation of realistic and diverse data samples. Among these models, diffusion models have emerged as a powerful approach for generating high-quality images, text, and…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Gaurav Raut , Apoorv Singh

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Deep generative models have shown impressive results in generating realistic images of faces. GANs managed to generate high-quality, high-fidelity images when conditioned on semantic masks, but they still lack the ability to diversify their…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Nico Giambi , Giuseppe Lisanti

While deep generative models~(DGMs) have demonstrated remarkable success in capturing complex data distributions, they consistently fail to learn constraints that encode domain knowledge and thus require constraint integration. Existing…

Machine Learning · Computer Science 2025-02-13 Ruoyan Li , Dipti Ranjan Sahu , Guy Van den Broeck , Zhe Zeng

Reconciling symbolic and distributed representations is a crucial challenge that can potentially resolve the limitations of current deep learning. Remarkable advances in this direction have been achieved recently via generative…

Machine Learning · Computer Science 2021-02-09 Jindong Jiang , Sungjin Ahn

We introduce nested diffusion models, an efficient and powerful hierarchical generative framework that substantially enhances the generation quality of diffusion models, particularly for images of complex scenes. Our approach employs a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xiao Zhang , Ruoxi Jiang , Rebecca Willett , Michael Maire

Generation of photo-realistic images, semantic editing and representation learning are a few of many potential applications of high resolution generative models. Recent progress in GANs have established them as an excellent choice for such…

Computer Vision and Pattern Recognition · Computer Science 2021-12-13 Partha Ghosh , Dominik Zietlow , Michael J. Black , Larry S. Davis , Xiaochen Hu

Reliable medical image classification requires accurate predictions and well-calibrated uncertainty estimates, especially in high-stakes clinical settings. This work presents MedSymmFlow, a generative-discriminative hybrid model built on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Francisco Caetano , Lemar Abdi , Christiaan Viviers , Amaan Valiuddin , Fons van der Sommen

Modeling disease progression is crucial for improving the quality and efficacy of clinical diagnosis and prognosis, but it is often hindered by a lack of longitudinal medical image monitoring for individual patients. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Xu Cao , Kaizhao Liang , Kuei-Da Liao , Tianren Gao , Wenqian Ye , Jintai Chen , Zhiguang Ding , Jianguo Cao , James M. Rehg , Jimeng Sun

The tremendous progress in neural image generation, coupled with the emergence of seemingly omnipotent vision-language models has finally enabled text-based interfaces for creating and editing images. Handling generic images requires a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Omri Avrahami , Ohad Fried , Dani Lischinski