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Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

Diagnostic Captioning (DC) automatically generates a diagnostic text from one or more medical images (e.g., X-rays, MRIs) of a patient. Treated as a draft, the generated text may assist clinicians, by providing an initial estimation of the…

Artificial Intelligence · Computer Science 2024-06-21 Panagiotis Kaliosis , John Pavlopoulos , Foivos Charalampakos , Georgios Moschovis , Ion Androutsopoulos

As a new emerging and promising type of generative models, diffusion models have proven to outperform Generative Adversarial Networks (GANs) in multiple tasks, including image synthesis. In this work, we explore semantic image synthesis for…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Yan Zhuang , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Boah Kim , Ronald M. Summers

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional…

Machine Learning · Computer Science 2025-10-23 Daniel Wesego

Deep generative models have shown promising results in generating realistic images, but it is still non-trivial to generate images with complicated structures. The main reason is that most of the current generative models fail to explore…

Machine Learning · Computer Science 2018-07-12 Kun Xu , Haoyu Liang , Jun Zhu , Hang Su , Bo Zhang

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

Large-scale generative models, such as text-to-image diffusion models, have garnered widespread attention across diverse domains due to their creative and high-fidelity image generation. Nonetheless, existing large-scale diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Younghyun Kim , Geunmin Hwang , Junyu Zhang , Eunbyung Park

By linking conceptual theories with observed data, generative models can support reasoning in complex situations. They have come to play a central role both within and beyond statistics, providing the basis for power analysis in molecular…

Methodology · Statistics 2022-08-15 Kris Sankaran , Susan P. Holmes

Masked generative models (MGMs) have shown impressive generative ability while providing an order of magnitude efficient sampling steps compared to continuous diffusion models. However, MGMs still underperform in image synthesis compared to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Jiwan Hur , Dong-Jae Lee , Gyojin Han , Jaehyun Choi , Yunho Jeon , Junmo Kim

This paper presents a novel approach for learned synergistic reconstruction of medical images using multibranch generative models. Leveraging variational autoencoders (VAEs), our model learns from pairs of images simultaneously, enabling…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Noel Jeffrey Pinton , Alexandre Bousse , Catherine Cheze-Le-Rest , Dimitris Visvikis

Graphs and networks are a key research tool for a variety of science fields, most notably chemistry, biology, engineering and social sciences. Modeling and generation of graphs with efficient sampling is a key challenge for graphs. In…

Machine Learning · Computer Science 2019-09-26 Ruud van Deursen , Guillaume Godin

Deep generative models have emerged as a powerful tool for learning useful molecular representations and designing novel molecules with desired properties, with applications in drug discovery and material design. However, most existing deep…

Deep generative models for graphs have exhibited promising performance in ever-increasing domains such as design of molecules (i.e, graph of atoms) and structure prediction of proteins (i.e., graph of amino acids). Existing work typically…

Machine Learning · Computer Science 2021-01-21 Wenbin Zhang , Liming Zhang , Dieter Pfoser , Liang Zhao

Content generation modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and task-oriented generation across diverse diagnostic tasks.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yuan Zhang , Xinfeng Zhang , Xiaoming Qi , Xinyu Wu , Feng Chen , Guanyu Yang , Huazhu Fu

Semantic medical image segmentation using deep learning has recently achieved high accuracy, making it appealing to clinical problems such as radiation therapy. However, the lack of high-quality semantically labelled data remains a…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Wei Dai , Siyu Liu , Craig B. Engstrom , Shekhar S. Chandra

Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Chang Qi , Junyang Chen , Guizhi Xu , Zhenghua Xu , Thomas Lukasiewicz , Yang Liu

The usage of deep generative models for image compression has led to impressive performance gains over classical codecs while neural video compression is still in its infancy. Here, we propose an end-to-end, deep generative modeling…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Jun Han , Salvator Lombardo , Christopher Schroers , Stephan Mandt
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