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Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Paul Friedrich , Yannik Frisch , Philippe C. Cattin

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Diffusion Generative Models (DGM) have rapidly surfaced as emerging topics in the field of computer vision, garnering significant interest across a wide array of deep learning applications. Despite their high computational demand, these…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Denisha Thakkar , Vincent Quoc-Huy Trinh , Sonal Varma , Samira Ebrahimi Kahou , Hassan Rivaz , Mahdi S. Hosseini

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xin Huang , Junjie Liang , Qingshan Hou , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Acquiring and annotating sufficient labeled data is crucial in developing accurate and robust learning-based models, but obtaining such data can be challenging in many medical image segmentation tasks. One promising solution is to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Kun Han , Yifeng Xiong , Chenyu You , Pooya Khosravi , Shanlin Sun , Xiangyi Yan , James Duncan , Xiaohui Xie

Recent advancements in generative models have revolutionized the field of artificial intelligence, enabling the creation of highly-realistic and detailed images. In this study, we propose a novel Mask Conditional Text-to-Image Generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Rami Skaik , Leonardo Rossi , Tomaso Fontanini , Andrea Prati

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Text-to-image diffusion models have demonstrated a remarkable ability to generate photorealistic images from natural language prompts. These high-resolution, language-guided synthesized images are essential for the explainability of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Zahra TehraniNasab , Amar Kumar , Tal Arbel

Recent advances in deep learning led to novel generative modeling techniques that achieve unprecedented quality in generated samples and performance in learning complex distributions in imaging data. These new models in medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Xiaoran Chen , Nick Pawlowski , Martin Rajchl , Ben Glocker , Ender Konukoglu

Generative models aim to learn the distribution of observed data by generating new instances. With the advent of neural networks, deep generative models, including variational autoencoders (VAEs), generative adversarial networks (GANs), and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Zifan Shi , Sida Peng , Yinghao Xu , Andreas Geiger , Yiyi Liao , Yujun Shen

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hazrat Ali , Shafaq Murad , Zubair Shah

Deep generative models (DGM) are neural networks with many hidden layers trained to approximate complicated, high-dimensional probability distributions using a large number of samples. When trained successfully, we can use the DGMs to…

Machine Learning · Computer Science 2021-04-13 Lars Ruthotto , Eldad Haber

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…

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