Related papers: Cyclic jetting enables microbubble-mediated drug d…
In a microfluidic environment, the presence of bubbles is often detrimental to the functionality of the device, leading to clogging or cavitation, but microbubbles can also be an indispensable asset in other applications such as…
The Worthington jets from bursting bubbles at a gas-liquid interface can break up into small droplets, aerosolizing chemical and biological substances into the atmosphere and impacting both global climate and public health. Despite their…
The formation and evolution of immersed surface micro- and nanobubbles are essential in various practical applications, such as the usage of superhydrophobic rematerials, drug delivery, and mineral flotation. In this work, we investigate…
One of the important applications of molecular communication is the targeted drug delivery process in which the drug molecules are released toward the target (receiver) in a way that the side effects are minimized in the human body. As the…
We explore air invasion in an initially water-filled dead-end compliant microchannel containing a constriction. The phenomenon is driven by the pervaporation of the liquid present in the channel through the surrounding medium. The…
We present an internal shocks model to investigate particle acceleration and radiation production in microquasar jets. The jet is modelled with discrete ejecta at various time intervals. These ejecta (or 'shells') may have different…
In this study, a computational simulation is employed to place two essential parameters, the permeability of vessels and hydraulic conductivity, under assessment. These parameters impact the movement of drug particles through vessels, and…
Colorectal cancer (CRC) continues to be a significant global health burden, prompting the need for more effective and targeted therapeutic strategies. Nanoparticle-based drug delivery systems have emerged as a promising approach to address…
A novel supersonic jet oscillating method is investigated both experimentally and numerically. A rectangular primary supersonic jet is issued into a confined chamber with sudden enlargement. Secondary control jets are issued from the top,…
Pressure changes travel at an infinite sound speed in an incompressible ideal fluid, opposite to what happens in a bubbly liquid, where the presence of bubbles adds compressibility such that the sound speed becomes finite. Here, the…
Fast liquid jets, called micro-jets, are produced within cavitation bubbles experiencing an aspherical collapse. Here we review micro-jets of different origins, scales and appearances, and propose a unified framework to describe their…
Within microcentrifuge devices, a microfluidic vortex separates larger particles from a heterogeneous suspension using inertial migration, a phenomenon that causes particles to migrate across streamlines. The ability to selectively capture…
We develop, analyse and numerically simulate a model of a prototype, glucose-driven, rhythmic drug delivery device, aimed at hormone therapies, and based on chemomechanical interaction in a polyelectrolyte gel membrane. The pH-driven…
In this paper, we develop an analytical model to investigate the generation of instability waves triggered by the upstream acoustic forcing near the nozzle lip of a supersonic jet. This represents an important stage, i.e. the jet…
The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected…
While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…
Fluids with internal microstructure like dense suspensions, biological and polymer added fluids, are commonly found in the turbulent regime in many applications. Their flow is extremely difficult to be studied as microstructure complexity…
We investigate a nonlinear multiphysics model motivated by ultrasound-enhanced drug delivery. The acoustic pressure field is modeled by Westervelt's quasilinear wave equation to adequately capture the nonlinear effects in ultrasound…
Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…
Bubble-driven inertial pumps are a novel method of moving liquids through microchannels. We combine high-speed imaging, computational fluid dynamics (CFD) simulations and an effective one-dimensional model to study the fundamentals of…