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By formulating data samples' formation as a Markov denoising process, diffusion models achieve state-of-the-art performances in a collection of tasks. Recently, many variants of diffusion models have been proposed to enable controlled…

Machine Learning · Computer Science 2023-04-17 Hengtong Zhang , Tingyang Xu

The Diffusion Probabilistic Model (DPM) has emerged as a highly effective generative model in the field of computer vision. Its intermediate latent vectors offer rich semantic information, making it an attractive option for various…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Haipeng Zhou , Lei Zhu , Yuyin Zhou

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

Biomolecules · Quantitative Biology 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu

Discrete diffusion models are a powerful class of generative models with strong performance across many domains. For efficiency, however, discrete diffusion typically parameterizes the generative (reverse) process with factorized…

Machine Learning · Statistics 2026-05-19 Grigory Bartosh , Teodora Pandeva , Sushrut Karmalkar , Javier Zazo

In data-driven drug discovery, designing molecular descriptors is a very important task. Deep generative models such as variational autoencoders (VAEs) offer a potential solution by designing descriptors as probabilistic latent vectors…

Machine Learning · Computer Science 2023-08-23 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

Masked diffusion language models (MDLMs) generate text via iterative masked-token denoising, enabling mask-parallel decoding and distinct controllability and efficiency tradeoffs from autoregressive LLMs. Yet, efficient representation-level…

Computation and Language · Computer Science 2026-03-31 Adi Shnaidman , Erin Feiglin , Osher Yaari , Efrat Mentel , Amit Levi , Raz Lapid

To fully leverage the capabilities of diffusion models, we are often interested in optimizing downstream reward functions during inference. While numerous algorithms for reward-guided generation have been recently proposed due to their…

Machine Learning · Computer Science 2025-04-18 Masatoshi Uehara , Xingyu Su , Yulai Zhao , Xiner Li , Aviv Regev , Shuiwang Ji , Sergey Levine , Tommaso Biancalani

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

Masked Diffusion Models (MDMs) offer flexible, non-autoregressive generation, but this freedom introduces a challenge: final output quality is highly sensitive to the decoding order. We are the first to formalize this issue, attributing the…

Computation and Language · Computer Science 2025-12-25 Ziyu Chen , Xinbei Jiang , Peng Sun , Tao Lin

Diffusion Models (DMs) have emerged as powerful generative models with unprecedented image generation capability. These models are widely used for data augmentation and creative applications. However, DMs reflect the biases present in the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Rishubh Parihar , Abhijnya Bhat , Abhipsa Basu , Saswat Mallick , Jogendra Nath Kundu , R. Venkatesh Babu

This paper investigates score-based diffusion models when the underlying target distribution is concentrated on or near low-dimensional manifolds within the higher-dimensional space in which they formally reside, a common characteristic of…

Machine Learning · Computer Science 2025-01-03 Gen Li , Yuling Yan

Discrete diffusion models have recently shown great promise for modeling complex discrete data, with masked diffusion models (MDMs) offering a compelling trade-off between quality and generation speed. MDMs denoise by progressively…

Machine Learning · Computer Science 2026-04-15 Tianyu Xie , Shuchen Xue , Zijin Feng , Tianyang Hu , Jiacheng Sun , Zhenguo Li , Cheng Zhang

Diffusion probabilistic models have quickly become a major approach for generative modeling of images, 3D geometry, video and other domains. However, to adapt diffusion generative modeling to these domains the denoising network needs to be…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Peiye Zhuang , Samira Abnar , Jiatao Gu , Alex Schwing , Joshua M. Susskind , Miguel Ángel Bautista

Masked diffusion models (MDMs) have emerged as a popular research topic for generative modeling of discrete data, thanks to their superior performance over other discrete diffusion models, and are rivaling the auto-regressive models (ARMs)…

Machine Learning · Computer Science 2025-05-01 Kaiwen Zheng , Yongxin Chen , Hanzi Mao , Ming-Yu Liu , Jun Zhu , Qinsheng Zhang

Recently, Masked Diffusion Models (MDMs) have shown promising potential across vision, language, and cross-modal generation. However, a notable discrepancy exists between their training and inference procedures. In particular, MDM inference…

Machine Learning · Computer Science 2025-12-30 Renping Zhou , Zanlin Ni , Tianyi Chen , Zeyu Liu , Yang Yue , Yulin Wang , Yuxuan Wang , Jingshu Liu , Gao Huang

Denoising diffusion probabilistic models (DDPM) are a class of generative models which have recently been shown to produce excellent samples. We show that with a few simple modifications, DDPMs can also achieve competitive log-likelihoods…

Machine Learning · Computer Science 2021-02-22 Alex Nichol , Prafulla Dhariwal

Latent dynamical models are commonly used to learn the distribution of a latent dynamical process that represents a sequence of noisy data samples. However, producing samples from such models with high fidelity is challenging due to the…

Machine Learning · Computer Science 2023-08-17 Mohammad R. Rezaei

Remote sensing change detection is crucial for understanding the dynamics of our planet's surface, facilitating the monitoring of environmental changes, evaluating human impact, predicting future trends, and supporting decision-making. In…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Wele Gedara Chaminda Bandara , Nithin Gopalakrishnan Nair , Vishal M. Patel

The fast fashion industry suffers from significant environmental impacts due to overproduction and unsold inventory. Accurately predicting sales volumes for unreleased products could significantly improve efficiency and resource…

Machine Learning · Computer Science 2024-12-11 Andrea Avogaro , Luigi Capogrosso , Franco Fummi , Marco Cristani

Denoising diffusion probabilistic models have recently demonstrated state-of-the-art generative performance and have been used as strong pixel-level representation learners. This paper decomposes the interrelation between the generative…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Zixuan Pan , Jianxu Chen , Yiyu Shi