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We use a continuum model to examine the effect of activity on a phase separating mixture of an extensile active nematic and a passive fluid. We highlight the distinct role of previously considered interfacial active stresses and bulk active…

Soft Condensed Matter · Physics 2022-12-26 Fernando Caballero , M. Cristina Marchetti

Active matter is not only indispensable to our understanding of diverse biological processes, but also provides a fertile ground for discovering novel physics. Many emergent properties impossible for equilibrium systems have been…

Soft Condensed Matter · Physics 2022-05-27 Thibault Bertrand , Chiu Fan Lee

Controlling interfaces of phase separating fluid mixtures is key to creating diverse functional soft materials. Traditionally, this is accomplished with surface-modifying chemical agents. Using experiment and theory, we study how mechanical…

Soft Condensed Matter · Physics 2022-08-15 Raymond Adkins , Itamar Kolvin , Zhihong You , Sven Witthaus , M. Cristina Marchetti , Zvonimir Dogic

In active systems, whose constituents have non-equilibrium dynamics at local level, fluid-fluid phase separation is widely observed. Examples include the formation of membraneless organelles within cells; the clustering of self-propelled…

Soft Condensed Matter · Physics 2025-07-11 M. E. Cates , C. Nardini

We study phase separation between coexisting active and passive fluids in three-dimensions, using numerical simulation and experiments. Chaotic flows of the active phase drive giant interfacial deformations, causing the co-existing phases…

Soft Condensed Matter · Physics 2026-02-16 Paarth Gulati , Liang Zhao , Michio Tateno , Omar A. Saleh , Zvonimir Dogic , M. Cristina Marchetti

Active matter, encompassing natural systems, converts surrounding energy to sustain autonomous motion, exhibiting unique non-equilibrium behaviors such as active turbulence and phase separation. In this study, we develop a continuum…

Soft Condensed Matter · Physics 2026-05-06 Sohail Ahmed , Zixiang Lin , Zijie Qu

Liquid-liquid phase separation has emerged as a fundamental mechanism underlying intracellular organization, with evidence for it being reported in numerous different systems. However, there is a growing concern regarding the lack of…

Soft Condensed Matter · Physics 2022-12-09 Mrityunjay Kothari , Tal Cohen

We propose a continuum theory of the liquid-liquid phase separation in an elastic network where phase-separated microscopic droplets rich in one fluid component can form as an interplay of fluids mixing, droplet nucleation, network…

Soft Condensed Matter · Physics 2021-01-04 Xuefeng Wei , Jiajia Zhou , Yanting Wang , Fanlong Meng

Active liquid crystals exert nonequilibrium stresses on their surroundings through constant consumption of energy, giving rise to dynamical steady states not present in equilibrium. The paradigmatic example of an active liquid crystal is a…

Soft Condensed Matter · Physics 2025-02-12 Paarth Gulati , Fernando Caballero , Itamar Kolvin , Zhihong You , M. Cristina Marchetti

We extend the continuum theories of active nematohydrodynamics to model a two-fluid mixture with separate velocity fields for each fluid component, coupled through a viscous drag. The model is used to study an active nematic fluid, mixed…

Soft Condensed Matter · Physics 2023-08-02 Saraswat Bhattacharyya , Julia M. Yeomans

Liquid-liquid phase separation is important across biology, physics, and materials science. Although usually studied at equilibrium, active components - such as motor proteins, enzymes, and synthetic microswimmers - are increasingly…

Soft Condensed Matter · Physics 2026-01-06 Kan Chang , Yulin Li , Ming Yuan , Masaki Sano , Zhihong You , H. P. Zhang

Phase separation is the thermodynamic process that explains how droplets form in multicomponent fluids. These droplets can provide controlled compartments to localize chemical reactions, and reactions can also affect the droplets' dynamics.…

Soft Condensed Matter · Physics 2022-09-02 David Zwicker

Liquid-liquid phase separation is key to understanding aqueous two-phase systems (ATPS) arising throughout cell biology, medical science, and the pharmaceutical industry. Controlling the detailed morphology of phase-separating compound…

Soft Condensed Matter · Physics 2023-10-27 Eric W. Hester , Sean P. Carney , Vishwesh Shah , Alyssa Arnheim , Bena Patel , Dino Di Carlo , Andrea L. Bertozzi

Active phase separations evade canonical thermodynamic descriptions and have thus challenged our understanding of coexistence and interfacial phenomena. Considerable progress has been made towards a non-equilibrium theoretical description…

Soft Condensed Matter · Physics 2025-04-21 Luke Langford , Ahmad K. Omar

We theoretically study mixtures of chemically-interacting particles, which produce or consume a chemical to which they are attracted or repelled, in the most general case of many coexisting species. We find a new class of active phase…

Soft Condensed Matter · Physics 2019-07-15 Jaime Agudo-Canalejo , Ramin Golestanian

Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

Fluid Dynamics · Physics 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

Demixing of binary liquids is a ubiquitous transition, which is explained using a well-established thermodynamic formalism that requires equality of intensive thermodynamics parameters across the phase boundaries. Demixing transitions also…

The motility-induced phase separation exhibited by active particles with repulsive interactions is well known. We show that the interaction softness of active particles destabilizes the highly ordered dense phase, leading to the formation…

Soft Condensed Matter · Physics 2022-09-21 Monika Sanoria , Raghunath Chelakkot , Amitabha Nandi

We consider a phenomenological continuum model for an active nematic fluid and show a universal, model independent, instability which renders the homogeneous nematic state unstable to order fluctuations. Using numerical and analytic tools…

Soft Condensed Matter · Physics 2014-10-15 Elias Putzig , Aparna Baskaran

The interplay between phase separation and wetting of multicomponent mixtures is ubiquitous in nature and technology and recently gained significant attention across scientific disciplines, due to the discovery of biomolecular condensates.…

Soft Condensed Matter · Physics 2022-10-14 Youchuang Chao , Olinka Ramirez-Soto , Christian Bahr , Stefan Karpitschka
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