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We document a fundamental paradox in AI transparency: explanations improve decisions when algorithms are correct but systematically worsen them when algorithms err. In an experiment with 257 medical students making 3,855 diagnostic…

General Economics · Economics 2025-12-10 Manshu Khanna , Ziyi Wang , Lijia Wei , Lian Xue

While reasoning-enhanced large language models perform strongly on English medical tasks, a persistent multilingual gap remains, with substantially weaker reasoning in local languages, limiting equitable global medical deployment. To bridge…

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

HealthBranches is a novel benchmark dataset for medical Question-Answering (Q&A), specifically designed to evaluate complex reasoning in Large Language Models (LLMs). This dataset is generated through a semi-automated pipeline that…

Computation and Language · Computer Science 2025-08-12 Cristian Cosentino , Annamaria Defilippo , Marco Dossena , Christopher Irwin , Sara Joubbi , Pietro Liò

This paper examines what it means for a medical AI system to be right by grounding the question in a specific clinical context: the automatic classification of plasma cells in digitized bone marrow smears for the diagnosis of multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Antony Gitau

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Machine learning promises to revolutionize clinical decision making and diagnosis. In medical diagnosis a doctor aims to explain a patient's symptoms by determining the diseases \emph{causing} them. However, existing diagnostic algorithms…

Machine Learning · Statistics 2020-03-17 Jonathan G. Richens , Ciaran M. Lee , Saurabh Johri

This paper addresses the problem of dialogue reasoning with contextualized commonsense inference. We curate CICERO, a dataset of dyadic conversations with five types of utterance-level reasoning-based inferences: cause, subsequent event,…

Computation and Language · Computer Science 2022-04-08 Deepanway Ghosal , Siqi Shen , Navonil Majumder , Rada Mihalcea , Soujanya Poria

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

When building artificial intelligence systems that can reason and answer questions about visual data, we need diagnostic tests to analyze our progress and discover shortcomings. Existing benchmarks for visual question answering can help,…

Computer Vision and Pattern Recognition · Computer Science 2016-12-22 Justin Johnson , Bharath Hariharan , Laurens van der Maaten , Li Fei-Fei , C. Lawrence Zitnick , Ross Girshick

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

Artificial Intelligence · Computer Science 2025-12-01 Michelle M. Li , Ben Y. Reis , Adam Rodman , Tianxi Cai , Noa Dagan , Ran D. Balicer , Joseph Loscalzo , Isaac S. Kohane , Marinka Zitnik

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Evaluating the clinical correctness and reasoning fidelity of automatically generated medical imaging reports remains a critical yet unresolved challenge. Existing evaluation methods often fail to capture the structured diagnostic logic…

Artificial Intelligence · Computer Science 2026-01-26 Suzhong Fu , Jingqi Dong , Xuan Ding , Rui Sun , Yiming Yang , Shuguang Cui , Zhen Li

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Medical fact-checking has become increasingly critical as more individuals seek medical information online. However, existing datasets predominantly focus on human-generated content, leaving the verification of content generated by large…

Computation and Language · Computer Science 2025-09-23 Tong Chen , Zimu Wang , Yiyi Miao , Haoran Luo , Yuanfei Sun , Wei Wang , Zhengyong Jiang , Procheta Sen , Jionglong Su

Legal judgments may contain errors due to the complexity of case circumstances and the abstract nature of legal concepts, while existing appellate review mechanisms face efficiency pressures from a surge in case volumes. Although current…

Computation and Language · Computer Science 2026-02-02 Yifei Li , Richong Zhang , Wanyu Tu , Zhijie Nie , Haokun Luo , Chuantao Yin , Pengchong Li

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li