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In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Lai Wei , Wenkai Wang , Xiaoyu Shen , Yu Xie , Zhihao Fan , Xiaojin Zhang , Zhongyu Wei , Wei Chen

In recent years, Multimodal Large Language Models (MLLM) have achieved notable advancements, demonstrating the feasibility of developing an intelligent biomedical assistant. However, current biomedical MLLMs predominantly focus on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Xiaoshuang Huang , Lingdong Shen , Jia Liu , Fangxin Shang , Hongxiang Li , Haifeng Huang , Yehui Yang

Learning medical visual representations directly from paired radiology reports has become an emerging topic in representation learning. However, existing medical image-text joint learning methods are limited by instance or local supervision…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Fuying Wang , Yuyin Zhou , Shujun Wang , Varut Vardhanabhuti , Lequan Yu

Recent advancements in Large Language Models (LLMs) and Large Multi-modal Models (LMMs) have shown potential in various medical applications, such as Intelligent Medical Diagnosis. Although impressive results have been achieved, we find…

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

Large Language Models (LLMs) have demonstrated remarkable generalization and instruction-following capabilities with instruction tuning. The advancements in LLMs and instruction tuning have led to the development of Large Vision-Language…

Machine Learning · Computer Science 2024-11-05 Jinyoung Park , Minseong Bae , Dohwan Ko , Hyunwoo J. Kim

Images in the medical domain are fundamentally different from the general domain images. Consequently, it is infeasible to directly employ general domain Visual Question Answering (VQA) models for the medical domain. Additionally, medical…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Yash Khare , Viraj Bagal , Minesh Mathew , Adithi Devi , U Deva Priyakumar , CV Jawahar

Vision-language models achieve expert-level performance on medical imaging tasks but exhibit significant diagnostic accuracy disparities across demographic groups. We introduce fairness-aware Low-Rank Adaptation for medical VLMs, combining…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zijian Gu , Yuxi Liu , Zhenhao Zhang , Song Wang

Medical AI assistants support doctors in disease diagnosis, medical image analysis, and report generation. However, they still face significant challenges in clinical use, including limited accuracy with multimodal content and insufficient…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Haonan Wang , Jiaji Mao , Lehan Wang , Qixiang Zhang , Marawan Elbatel , Yi Qin , Huijun Hu , Baoxun Li , Wenhui Deng , Weifeng Qin , Hongrui Li , Jialin Liang , Jun Shen , Xiaomeng Li

Recently, there has been great success in leveraging pre-trained large language models (LLMs) for time series analysis. The core idea lies in effectively aligning the modality between natural language and time series. However, the…

Machine Learning · Computer Science 2026-03-03 Zongjiang Shang , Dongliang Cui , Binqing Wu , Ling Chen

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Multimodal Large Language Models (MLLMs) pose critical safety challenges, as they are susceptible not only to adversarial attacks such as jailbreaking but also to inadvertently generating harmful content for benign users. While internal…

Machine Learning · Computer Science 2026-03-17 Ming Wen , Kun Yang , Xin Chen , Jingyu Zhang , Dingding Han , Shiwen Cui , Yuedong Xu

Multimodal large language models are typically trained in two stages: first pre-training on image-text pairs, and then fine-tuning using supervised vision-language instruction data. Recent studies have shown that large language models can…

Machine Learning · Computer Science 2026-04-14 Lai Wei , Xiaozhe Li , Zihao Jiang , Weiran Huang , Lichao Sun

Vision-language pretraining has driven significant progress in medical image analysis. However, current methods typically supervise visual encoders using one-hot labels or free-form text, neither of which effectively captures the complex…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xiyao Wang , Xiaoyu Tan , Yang Dai , Yuxuan Fu , Shuo Li , Xihe Qiu

Multi-modal large language models (MLLMs) have made significant strides in various visual understanding tasks. However, the majority of these models are constrained to process low-resolution images, which limits their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Xiangyu Zhao , Xiangtai Li , Haodong Duan , Haian Huang , Yining Li , Kai Chen , Hua Yang

Vision Language Models (VLMs) achieved rapid progress in the recent years. However, despite their growth, VLMs development is heavily grounded on English, leading to two main limitations: (i) the lack of multilingual and multimodal datasets…

Computation and Language · Computer Science 2026-04-21 Daniela Baiamonte , Elena Fano , Matteo Gabburo , Stefano Simonazzi , Leonardo Rigutini , Andrea Zugarini

The paper introduces ExKG-LLM, a framework designed to automate the expansion of cognitive neuroscience knowledge graphs (CNKG) using large language models (LLMs). It addresses limitations in existing tools by enhancing accuracy,…

Artificial Intelligence · Computer Science 2025-07-09 Ali Sarabadani , Kheirolah Rahsepar Fard , Hamid Dalvand

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

In this research, we explored the improvement in terms of multi-class disease classification via pre-trained language models over Medical-Abstracts-TC-Corpus that spans five medical conditions. We excluded non-cancer conditions and examined…

Computation and Language · Computer Science 2024-11-20 Ahmed Akib Jawad Karim , Muhammad Zawad Mahmud , Samiha Islam , Aznur Azam

In the U.S. inpatient payment system, the Diagnosis-Related Group (DRG) is pivotal, but its assignment process is inefficient. The study introduces DRG-LLaMA, an advanced large language model (LLM) fine-tuned on clinical notes to enhance…

Artificial Intelligence · Computer Science 2023-10-02 Hanyin Wang , Chufan Gao , Christopher Dantona , Bryan Hull , Jimeng Sun