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In the field of chemistry, the objective is to create novel molecules with desired properties, facilitating accurate property predictions for applications such as material design and drug screening. However, existing graph deep learning…

Machine Learning · Computer Science 2024-08-28 Sakhinana Sagar Srinivas , Venkataramana Runkana

The research community has witnessed the powerful potential of self-supervised Masked Image Modeling (MIM), which enables the models capable of learning visual representation from unlabeled data. In this paper, to incorporate both the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Wenxuan Wang , Jing Wang , Chen Chen , Jianbo Jiao , Yuanxiu Cai , Shanshan Song , Jiangyun Li

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

Machine Learning · Computer Science 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

Recent advancements in semantic communication have primarily focused on image transmission, where neural network-based joint source-channel coding modules play a central role. However, such systems often experience semantic communication…

Signal Processing · Electrical Eng. & Systems 2026-02-20 Yoon Huh , Bumjun Kim , Wan Choi

Unlike vision and language data which usually has a unique format, molecules can naturally be characterized using different chemical formulations. One can view a molecule as a 2D graph or define it as a collection of atoms located in a 3D…

Machine Learning · Computer Science 2023-03-29 Shengjie Luo , Tianlang Chen , Yixian Xu , Shuxin Zheng , Tie-Yan Liu , Liwei Wang , Di He

The Abstract Meaning Representation (AMR) is a representation for open-domain rich semantics, with potential use in fields like event extraction and machine translation. Node generation, typically done using a simple dictionary lookup, is…

Computation and Language · Computer Science 2015-06-11 Keenon Werling , Gabor Angeli , Christopher Manning

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

Designing a neural network architecture for molecular representation is crucial for AI-driven drug discovery and molecule design. In this work, we propose a new framework for molecular representation learning. Our contribution is threefold:…

Machine Learning · Computer Science 2022-10-18 Jiye Kim , Seungbeom Lee , Dongwoo Kim , Sungsoo Ahn , Jaesik Park

Factorization machine (FM) is an effective model for feature-based recommendation which utilizes inner product to capture second-order feature interactions. However, one of the major drawbacks of FM is that it couldn't capture complex…

Machine Learning · Computer Science 2024-04-03 Enneng Yang , Xin Xin , Li Shen , Guibing Guo

While Transformers have revolutionized deep learning, their quadratic attention complexity hinders their ability to process infinitely long inputs. We propose Feedback Attention Memory (FAM), a novel Transformer architecture that leverages…

Machine Learning · Computer Science 2024-05-08 Dongseong Hwang , Weiran Wang , Zhuoyuan Huo , Khe Chai Sim , Pedro Moreno Mengibar

This paper addresses the problems of missing reasoning chains and insufficient entity-level semantic understanding in large language models when dealing with tasks that require structured knowledge. It proposes a fine-tuning algorithm…

Computation and Language · Computer Science 2025-08-21 Wuyang Zhang , Yexin Tian , Xiandong Meng , Mengjie Wang , Junliang Du

In the computational prediction of chemical compound properties, molecular descriptors and fingerprints encoded to low dimensional vectors are used. The selection of proper molecular descriptors and fingerprints is both important and…

Machine Learning · Computer Science 2020-10-23 Sangrak Lim , Yong Oh Lee

Molecular-level understanding of the interactions between the constituents of an atomic structure is essential for designing novel materials in various applications. This need goes beyond the basic knowledge of the number and types of…

The discovery of novel materials and functional molecules can help to solve some of society's most urgent challenges, ranging from efficient energy harvesting and storage to uncovering novel pharmaceutical drug candidates. Traditionally…

Machine Learning · Computer Science 2020-11-06 Mario Krenn , Florian Häse , AkshatKumar Nigam , Pascal Friederich , Alán Aspuru-Guzik

Micro-expression Action Unit (AU) detection identifies localized AUs from subtle facial muscle activations, providing a foundation for decoding affective cues. Previous methods face three key limitations: (1) heavy reliance on low-density…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Zhishu Liu , Kaishen Yuan , Bo Zhao , Hui Ma , Zitong Yu

Recent years have witnessed rapid advances in graph representation learning, with the continuous embedding approach emerging as the dominant paradigm. However, such methods encounter issues regarding parameter efficiency, interpretability,…

Machine Learning · Computer Science 2026-01-22 Qika Lin , Zhen Peng , Kaize Shi , Kai He , Yiming Xu , Jian Zhang , Erik Cambria , Mengling Feng

In this work, we propose a simple transformer-based baseline for multimodal molecular representation learning, integrating three distinct modalities: SMILES strings, 2D graph representations, and 3D conformers of molecules. A key aspect of…

Machine Learning · Computer Science 2024-10-25 Andrei Manolache , Dragos Tantaru , Mathias Niepert

Recently, large language models (LLMs) have been explored for integration with collaborative filtering (CF)-based recommendation systems, which are crucial for personalizing user experiences. However, a key challenge is that LLMs struggle…

Information Retrieval · Computer Science 2025-10-20 Chao Wang , Yixin Song , Jinhui Ye , Chuan Qin , Dazhong Shen , Lingfeng Liu , Xiang Wang , Yanyong Zhang

Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are…

Quantitative Methods · Quantitative Biology 2017-05-01 Mona Alshahrani , Mohammed Asif Khan , Omar Maddouri , Akira R Kinjo , Núria Queralt-Rosinach , Robert Hoehndorf

Graph Transformers have recently attracted attention for molecular property prediction by combining the inductive biases of graph neural networks (GNNs) with the global receptive field of Transformers. However, many existing hybrid…

Machine Learning · Computer Science 2026-04-09 Yi Yang , Ovidiu Daescu