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The computational burden of attention in long-context language models has motivated two largely independent lines of work: sparse attention mechanisms that reduce complexity by attending to selected tokens, and gated attention variants that…

Artificial Intelligence · Computer Science 2026-01-23 Alfred Shen , Aaron Shen

Token prediction stability remains a challenge in autoregressive generative models, where minor variations in early inference steps often lead to significant semantic drift over extended sequences. A structured modulation mechanism was…

Spatial transcriptomics (ST) is a novel technology that enables the observation of gene expression at the resolution of individual spots within pathological tissues. ST quantifies the expression of tens of thousands of genes in a tissue…

Machine Learning · Computer Science 2025-11-25 Kaito Shiku , Kazuya Nishimura , Shinnosuke Matsuo , Yasuhiro Kojima , Ryoma Bise

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

Genomics · Quantitative Biology 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

Genomic (DNA) sequences encode an enormous amount of information for gene regulation and protein synthesis. Similar to natural language models, researchers have proposed foundation models in genomics to learn generalizable features from…

Investigating the causal relationships between characteristics and expressions plays a critical role in healthcare analytics. Effective synthesis for expressions using given characteristics can make great contributions to health risk…

Machine Learning · Statistics 2022-05-31 Yuxuan Li , Ying Lin , Chenang Liu

Conditional GANs are widely used in translating an image from one category to another. Meaningful conditions to GANs provide greater flexibility and control over the nature of the target domain synthetic data. Existing conditional GANs…

Computer Vision and Pattern Recognition · Computer Science 2020-09-09 Binod Bhattarai , Tae-Kyun Kim

We introduce and experimentally demonstrate the utility of tag-based genetic regulation, a new genetic programming (GP) technique that allows programs to dynamically adjust which code modules to express. Tags are evolvable labels that…

Neural and Evolutionary Computing · Computer Science 2021-07-13 Alexander Lalejini , Matthew Andres Moreno , Charles Ofria

Programming languages possess rich semantic information - such as data flow - that is represented by graphs and not available from the surface form of source code. Recent code language models have scaled to billions of parameters, but model…

Computation and Language · Computer Science 2025-09-24 Ziyin Zhang , Hang Yu , Shijie Li , Peng Di , Jianguo Li , Rui Wang

Prior to the deployment of robotic systems, pre-training the deep-recognition models on all potential visual cases is infeasible in practice. Hence, test-time adaptation (TTA) allows the model to adapt itself to novel environments and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Junha Song , Kwanyong Park , InKyu Shin , Sanghyun Woo , Chaoning Zhang , In So Kweon

Large language models (LLMs) have demonstrated remarkable advancements, primarily due to their capabilities in modeling the hidden relationships within text sequences. This innovation presents a unique opportunity in the field of life…

Genomics · Quantitative Biology 2024-12-25 Cong Li , Qingqing Long , Yuanchun Zhou , Meng Xiao

Despite the dramatic success in image generation, Generative Adversarial Networks (GANs) still face great challenges in synthesizing sequences of discrete elements, in particular human language. The difficulty in generator training arises…

Computation and Language · Computer Science 2023-02-24 Yekun Chai , Qiyue Yin , Junge Zhang

Developing models with high interpretability and even deriving formulas to quantify relationships between biological data is an emerging need. We propose here a framework for ab initio derivation of sequence motifs and linear formula using…

Quantitative Methods · Quantitative Biology 2022-08-23 Chengyu Liu , Wei Wang

Cellular automata have been useful artificial models for exploring how relatively simple rules combined with spatial memory can give rise to complex emergent patterns. Moreover, studying the dynamics of how rules emerge under artificial…

Cellular Automata and Lattice Gases · Physics 2014-07-11 Theodore P. Pavlic , Alyssa M. Adams , Paul C. W. Davies , Sara Imari Walker

Large, pretrained language models infer powerful representations that encode rich semantic and syntactic content, albeit implicitly. In this work we introduce a novel neural language model that enforces, via inductive biases, explicit…

Computation and Language · Computer Science 2023-05-29 Ramsés J. Sánchez , Lukas Conrads , Pascal Welke , Kostadin Cvejoski , César Ojeda

Understanding the neural implementation of complex human behaviors is one of the major goals in neuroscience. To this end, it is crucial to find a true representation of the neural data, which is challenging due to the high complexity of…

Machine Learning · Computer Science 2023-08-15 Cheol Jun Cho , Edward F. Chang , Gopala K. Anumanchipalli

Answer selection (answer ranking) is one of the key steps in many kinds of question answering (QA) applications, where deep models have achieved state-of-the-art performance. Among these deep models, recurrent neural network (RNN) based…

Computation and Language · Computer Science 2019-05-28 Dong Xu , Jianhui Ji , Haikuan Huang , Hongbo Deng , Wu-Jun Li

While recent advancements in speech language models have achieved significant progress, they face remarkable challenges in modeling the long acoustic sequences of neural audio codecs. In this paper, we introduce \textbf{G}enerative…

Computation and Language · Computer Science 2024-11-04 Yongxin Zhu , Dan Su , Liqiang He , Linli Xu , Dong Yu

This paper introduces a reinforcement learning (RL) approach to address the challenges associated with configuring and optimizing genetic algorithms (GAs) for solving difficult combinatorial or non-linear problems. The proposed RL+GA method…

Performance achievable by modern deep learning approaches are directly related to the amount of data used at training time. Unfortunately, the annotation process is notoriously tedious and expensive, especially for pixel-wise tasks like…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Pierluigi Zama Ramirez , Alessio Tonioni , Luigi Di Stefano