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Large Language Models (LLMs), such as Generative Pre-trained Transformers (GPTs) are revolutionizing the generation of human-like text, producing contextually relevant and syntactically correct content. Despite challenges like biases and…

Computation and Language · Computer Science 2025-08-04 Alper Yaman , Jannik Schwab , Christof Nitsche , Abhirup Sinha , Marco Huber

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

We propose a novel convolutional architecture, named $gen$CNN, for word sequence prediction. Different from previous work on neural network-based language modeling and generation (e.g., RNN or LSTM), we choose not to greedily summarize the…

Computation and Language · Computer Science 2015-04-27 Mingxuan Wang , Zhengdong Lu , Hang Li , Wenbin Jiang , Qun Liu

Speech-LLM models have demonstrated great performance in multi-modal and multi-task speech understanding. A typical speech-LLM paradigm is integrating speech modality with a large language model (LLM). While the Whisper encoder was…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-11 Wei Liu , Jiahong Li , Yiwen Shao , Dong Yu

In standard genetic programming (stdGP), solutions are varied by modifying their syntax, with uncertain effects on their semantics. Geometric-semantic genetic programming (GSGP), a popular variant of GP, effectively searches the semantic…

Neural and Evolutionary Computing · Computer Science 2025-01-31 Philipp Anthes , Dominik Sobania , Franz Rothlauf

Generic generation and manipulation of text is challenging and has limited success compared to recent deep generative modeling in visual domain. This paper aims at generating plausible natural language sentences, whose attributes are…

Machine Learning · Computer Science 2018-09-14 Zhiting Hu , Zichao Yang , Xiaodan Liang , Ruslan Salakhutdinov , Eric P. Xing

In the last years, tens of thousands gene expression profiles for cells of several organisms have been monitored. Gene expression is a complex transcriptional process where mRNA molecules are translated into proteins, which control most of…

Biomolecules · Quantitative Biology 2009-11-11 T. Ochiai , J. C. Nacher , T. Akutsu

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Prompt tuning, a recently emerging paradigm, enables the powerful vision-language pre-training models to adapt to downstream tasks in a parameter -- and data -- efficient way, by learning the ``soft prompts'' to condition frozen…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Juncheng Li , Minghe Gao , Longhui Wei , Siliang Tang , Wenqiao Zhang , Mengze Li , Wei Ji , Qi Tian , Tat-Seng Chua , Yueting Zhuang

The gene set analysis (GSA) is a foundational approach for uncovering the molecular functions associated with a group of genes. Recently, LLM-powered methods have emerged to annotate gene sets with biological functions together with…

Genomics · Quantitative Biology 2025-09-16 Zhizheng Wang , Yifan Yang , Qiao Jin , Zhiyong Lu

Automated Short Answer Scoring (ASAS) is a critical component in educational assessment. While traditional ASAS systems relied on rule-based algorithms or complex deep learning methods, recent advancements in Generative Language Models…

Computation and Language · Computer Science 2024-08-08 Zifan Wang , Christopher Ormerod

Temporal expressions in text play a significant role in language understanding and correctly identifying them is fundamental to various retrieval and natural language processing systems. Previous works have slowly shifted from rule-based to…

Computation and Language · Computer Science 2022-01-25 Satya Almasian , Dennis Aumiller , Michael Gertz

Attention-based models trained on protein sequences have demonstrated incredible success at classification and generation tasks relevant for artificial intelligence-driven protein design. However, we lack a sufficient understanding of how…

Machine Learning · Computer Science 2022-06-29 Erik Nijkamp , Jeffrey Ruffolo , Eli N. Weinstein , Nikhil Naik , Ali Madani

The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…

Populations and Evolution · Quantitative Biology 2026-04-30 Leonardo Ivan Estrella Dzib , James Holehouse

Large language models (LLMs) augmented with retrieval systems have significantly advanced natural language processing tasks by integrating external knowledge sources, enabling more accurate and contextually rich responses. To improve the…

Computation and Language · Computer Science 2025-05-28 Xin Sun , Jianan Xie , Zhongqi Chen , Qiang Liu , Shu Wu , Yuehe Chen , Bowen Song , Weiqiang Wang , Zilei Wang , Liang Wang

We apply topological data analysis (TDA) to speech classification problems and to the introspection of a pretrained speech model, HuBERT. To this end, we introduce a number of topological and algebraic features derived from Transformer…

Training generative adversarial networks (GANs) with limited data is challenging because the discriminator is prone to overfitting. Previously proposed differentiable augmentation demonstrates improved data efficiency of training GANs.…

Machine Learning · Computer Science 2023-12-29 Liang Hou , Qi Cao , Yige Yuan , Songtao Zhao , Chongyang Ma , Siyuan Pan , Pengfei Wan , Zhongyuan Wang , Huawei Shen , Xueqi Cheng

Predicting how cells respond to genetic perturbations is fundamental to understanding gene function, disease mechanisms, and therapeutic development. While recent deep learning approaches have shown promise in modeling single-cell…

Machine Learning · Computer Science 2026-03-10 Andrea Giuseppe Di Francesco , Andrea Rubbi , Pietro Liò

Cross-modal alignment is one key challenge for Vision-and-Language Navigation (VLN). Most existing studies concentrate on mapping the global instruction or single sub-instruction to the corresponding trajectory. However, another critical…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yibo Cui , Liang Xie , Yakun Zhang , Meishan Zhang , Ye Yan , Erwei Yin

Recent progress in the task of Grammatical Error Correction (GEC) has been driven by addressing data sparsity, both through new methods for generating large and noisy pretraining data and through the publication of small and higher-quality…

Computation and Language · Computer Science 2020-09-10 Jared Lichtarge , Chris Alberti , Shankar Kumar
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