Related papers: FlexLMM: a Nextflow linear mixed model framework f…
Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…
Flow matching casts sample generation as learning a continuous-time velocity field that transports noise to data. Existing flow matching networks typically predict each point's velocity independently, considering only its location and time…
A connection between the General Linear Model (GLM) in combination with classical statistical inference and the machine learning (MLE)-based inference is described in this paper. Firstly, the estimation of the GLM parameters is expressed as…
Standard flow matching scales well but typically relies on an unstructured source distribution, limiting its ability to learn interpretable latent structure. Latent-variable models, by contrast, capture structure but often sacrifice…
The standard procedures for analysing hierarquical or grouped data are by (non)linear mixed models or generalized mixed models. However, the generalized additive models for location, scale and shape (GAMLSSs) also allow different types of…
Motivated by genome-wide association studies, we consider a standard linear model with one additional random effect in situations where many predictors have been collected on the same subjects and each predictor is analyzed separately.…
Flow-based generative models are a family of exact log-likelihood models with tractable sampling and latent-variable inference, hence conceptually attractive for modeling complex distributions. However, flow-based models are limited by…
We provide a theoretical analysis for end-to-end training Discrete Flow Matching (DFM) generative models. DFM is a promising discrete generative modeling framework that learns the underlying generative dynamics by training a neural network…
Neural networks are increasingly used to support decision-making. To verify their reliability and adaptability, researchers and practitioners have proposed a variety of tools and methods for tasks such as NN code verification, refactoring,…
Using Large Language Models (LLMs) to process graph-structured data is an active research area, yet current state-of-the-art approaches typically rely on multi-step pipelines with Graph Neural Network (GNN) encoders that compress rich…
The performance of large language models (LLMs) and large multimodal models (LMMs) depends heavily on the quality and scale of their pre-training datasets. Recent research shows that large multimodal models trained on natural documents…
In federated graph learning (FGL), a complete graph is divided into multiple subgraphs stored in each client due to privacy concerns, and all clients jointly train a global graph model by only transmitting model parameters. A pain point of…
The standard regression tree method applied to observations within clusters poses both methodological and implementation challenges. Effectively leveraging these data requires methods that account for both individual-level and sample-level…
Recently, large language models (LLMs) have been successfully applied to many fields, showing outstanding comprehension and reasoning capabilities. Despite their great potential, LLMs usually require dedicated pre-training and fine-tuning…
Existing pretraining data mixing methods for large language models (LLMs) typically follow a domain-wise methodology, a top-down process that first determines domain weights and then performs uniform data sampling across each domain.…
The effectiveness of the machine learning methods for real-world tasks depends on the proper structure of the modeling pipeline. The proposed approach is aimed to automate the design of composite machine learning pipelines, which is…
Downsampling or under-sampling is a technique that is utilized in the context of large and highly imbalanced classification models. We study optimal downsampling for imbalanced classification using generalized linear models (GLMs). We…
In evolutionary dynamics, well-mixed populations are almost always associated with all-to-all interactions; mathematical models are based on complete graphs. In most cases, these models do not predict fixation probabilities in groups of…
Large language models (LLMs) underpin applications in code generation, mathematical reasoning, and agent-based workflows. In practice, systems access LLMs via commercial APIs or open-source deployments, and the model landscape (e.g., GPT,…
The envelope model provides a dimension-reduction framework for multivariate linear regression. However, existing envelope methods typically assume normally distributed random errors and do not accommodate repeated measures in longitudinal…